Inventor

VOLANTE RALPH P

US65 patents

⚠️ This page may combine multiple inventors who share the name “VOLANTE RALPH P”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

VOLANTE RALPH P

MERCK & CO INC

Process for C-methylation of 2-methylbutyrates

Process for the preparation of leukotriene anatgonists

Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein

Process for the preparation of leukotriene antagonists

Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors

Process for making phenyl heterocycles useful as cox-2 inhibitors

Facile condensation of methylbenzoxazoles with aromatic aldehydes

Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors

Process for the preparation of a growth hormone secretagogue

Preparation of beta-methyl carbapenem intermediates

Process for the preparation of N-formimidoyl thienamycin and reagents therefor

Process for synthesis of 1R,2R,5R-2-hydroxy-6-oxo-7-oxabicyclo[3.2.1]-octane

Novel hydroxide mediated FK-506 rearrangement process

Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

Chiral bisphosphines

Process for preparing 4-tert-butyloxycarbonyl-(S)-piperazine-2-tert-butylcarboxamide

Process for making HIV protease inhibitors

Process for making HIV protease inhibitors

Process for making HIV protease inhibitors

Process for synthesis of FK-506 and tricarbonyl intermediates

Intermediates for making heterocycles useful as COX-2 inhibitors

Process for making an epoxide

Process for the conversion of primary and secondary alcohols to their corresponding thiols and thiol esters

HIV protease inhibitor

Processes and intermediates for the preparation of 5-oxygenated hmg-coa reductase inhibitors

Process for synthesizing carbapenem intermediates using a rhodium catalyst and lewis acid

Preparation of beta-methyl carbapenem intermediates

Process for synthesis of FK-506 intermediates

Hydroxide mediated FK-506 rearrangement product

Process for synthesis of E-2-methyl-α,β-unsaturated aldehydes

Process for the preparation of HMG-CoA reductase inhibitors intermediates

Chiral bisphosphines

Process for making HIV protease inhibitors

Process for making HIV protease inhibitors

Process for making HIV protease inhibitors

Process for the preparation of 4-acyloxyazetidin-2-one by electrochemical methods

Process for certain (2R-trans)hexahydroaroquinolizines

Process for the preparation of 4-acyloxyazetidin-2-one by singlet oxygen oxidation

Oxidation and reduction method to produce 4-acyloxyazetidin-2-one

Process for the preparation of HMG-CoA reductase inhibitors

Process to make HIV protease inhibitor from (2S)-4-picolyl-2-piperazine-t-butylcarboxamide

Process for making spirolactone compounds

Process for the preparation of 4-chloro-2-cyclopropylcarbonylaniline

Process for optically pure decahydroisoqiunolines

Method of preparing phosphodiesterase IV inhibitors

Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one

FK-506 type macrolide intermediate

Diastereoselective preparation of Michael adducts

MERCK & CO LTD

Method of synthesizing furo[2,3-b]pyridine carboxylic acid esters

(unassigned)

Process for the synthesis of carbapenem intermidiates, and compounds produced