Inventor

MARTIN JERRY R

US42 patents

Patents

42 patents

US4124756ANov 7, 1978

2'N-Acyl and alkyl-6'-N-alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B

ABBOTT LAB7 citations74

US4187296AFeb 5, 1980

2-N-acyl and alkyl 6-epi-fortimicin B and derivatives

ABBOTT LAB11 citations74

US4319022AMar 9, 1982

2-O-Substituted sulfonyl derivatives of fortimicin B

ABBOTT LAB7 citations73

US4317904AMar 2, 1982

1,2-Epiminofortimicin B

ABBOTT LAB7 citations73

US4192867AMar 11, 1980

2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives

ABBOTT LAB10 citations73

US4187298AFeb 5, 1980

2'N-acyl and alkyl fortimicin B and derivatives, 4,2'-N,N'diacyl and dialkyl fortimicin B derivatives 4-N-acyl-2'-N-alkyl and 4-N-alkyl-2'-N-acyl fortimicin B derivatives

ABBOTT LAB10 citations73

US4187297AFeb 5, 1980

3-De-O-methyl-2-N-acyl and alkyl fortimicins A and B

ABBOTT LAB17 citations73

US4183920AJan 15, 1980

4-N-Acyl, 2'-N-acyl and 4,2'-N,N'-diacylfortimicin E derivatives

ABBOTT LAB9 citations73

US4176178ANov 27, 1979

2-Deoxy-2'-N-acyl and alkyl fortimicins A and B

ABBOTT LAB15 citations73

US4251516AFeb 17, 1981

2-Deoxy-3-O-Demethylfortimicins

ABBOTT LAB12 citations72

US4250304AFeb 10, 1981

2-Deoxy-2-substituted fortimicin A and B and derivatives

ABBOTT LAB11 citations72

US4213972AJul 22, 1980

4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI

ABBOTT LAB2 citations63

US4213974AJul 22, 1980

4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives

ABBOTT LAB2 citations63

US4214075AJul 22, 1980

6'-Epi-fortimicin A and B derivatives

ABBOTT LAB4 citations63

US4214079AJul 22, 1980

4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives

ABBOTT LAB2 citations63

US4360666ANov 23, 1982

2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives and intermediates therefor

ABBOTT LAB2 citations62

US4276413AJun 30, 1981

Fortimicin intermediates for producing 2-deoxyfortimicins

ABBOTT LAB3 citations62

US4273924AJun 16, 1981

2-O-Hydrocarbonsulfonyl-4,5-oxazolidine fortimicin B derivatives

ABBOTT LAB2 citations62

US4231924ANov 4, 1980

4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

ABBOTT LAB2 citations62

US4208407AJun 17, 1980

5-Deoxyfortimicin A, 2,5-dideoxyfortimicin A and the corresponding 4-N-acyl and alkyl fortimicin B derivatives thereof and intermediates therefor

ABBOTT LAB2 citations62

US4207415AJun 10, 1980

Method of producing 2-deoxyfortimicin A

ABBOTT LAB3 citations62

US4155902AMay 22, 1979

4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

ABBOTT LAB4 citations62

US4309342AJan 5, 1982

Antibacterial peptides

ABBOTT LAB4 citations61

US4205070AMay 27, 1980

6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B

ABBOTT LAB4 citations60

US4264590AApr 28, 1981

Antibacterial peptide

ABBOTT LAB5 citations53

US4360668ANov 23, 1982

2-O-Methanesulfonylfortimicin B

ABBOTT LAB0 citations52

US4360667ANov 23, 1982

(1,2',6'-Tri-N-(2-O-methanesulfonylsalicylidine)-4,5-(2-O-methanesulfonylsalicylaldehyde) oxazolidine-2-O-methanesulfonylfortimicin B

ABBOTT LAB0 citations52

US4269970AMay 26, 1981

1,2-Carbamates of fortimicin B and derivatives

ABBOTT LAB1 citations52

US4263429AApr 21, 1981

1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate

ABBOTT LAB0 citations52

US4232147ANov 4, 1980

4-N-Acylfortimicin B-1,5-carbamates

ABBOTT LAB1 citations52

US4230846AOct 28, 1980

1,5-Carbamates of fortimicin B and derivatives

ABBOTT LAB0 citations52

US4431799AFeb 14, 1984

6'-Modified fortimicin compounds

ABBOTT LAB1 citations51

US4331804AMay 25, 1982

2-Epi-fortimicin A and derivatives

ABBOTT LAB1 citations51

US4188319AFeb 12, 1980

4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

ABBOTT LAB0 citations51

US4174312ANov 13, 1979

4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

ABBOTT LAB1 citations51

US4173564ANov 6, 1979

4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

ABBOTT LAB1 citations51

US4340727AJul 20, 1982

1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture

ABBOTT LAB0 citations50

US4273925AJun 16, 1981

1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture

ABBOTT LAB0 citations50

US4275193AJun 23, 1981

4,5-Carbamates of fortimicin B

ABBOTT LAB0 citations42

MARTIN JERRY R

Patents

3-DE-O-Methylfortimicins

2-Deoxyfortimicin B

Fortimicin B-1,2:4,5-bis-carbamates

2&#39;N-Acyl and alkyl-6&#39;-N-alkyl- and 6&#39;,6&#39;-di-N-alkyl derivatives of fortimicins A and B

2-N-acyl and alkyl 6-epi-fortimicin B and derivatives

2-O-Substituted sulfonyl derivatives of fortimicin B

1,2-Epiminofortimicin B

2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives

2&#39;N-acyl and alkyl fortimicin B and derivatives, 4,2&#39;-N,N&#39;diacyl and dialkyl fortimicin B derivatives 4-N-acyl-2&#39;-N-alkyl and 4-N-alkyl-2&#39;-N-acyl fortimicin B derivatives

3-De-O-methyl-2-N-acyl and alkyl fortimicins A and B

4-N-Acyl, 2&#39;-N-acyl and 4,2&#39;-N,N&#39;-diacylfortimicin E derivatives

2-Deoxy-2&#39;-N-acyl and alkyl fortimicins A and B

2-Deoxy-3-O-Demethylfortimicins

2-Deoxy-2-substituted fortimicin A and B and derivatives

4-N, 2&#39;-N and 4,2&#39;Di-N-fortimicins AH and AI

4-N,2&#39;-N and 4,2&#39;-Di-N-fortimicin AO derivatives

6&#39;-Epi-fortimicin A and B derivatives

4-N, 2&#39;-N and 4,2&#39;-Di-N-fortimicin AL derivatives

2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives and intermediates therefor

Fortimicin intermediates for producing 2-deoxyfortimicins

2-O-Hydrocarbonsulfonyl-4,5-oxazolidine fortimicin B derivatives

4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

5-Deoxyfortimicin A, 2,5-dideoxyfortimicin A and the corresponding 4-N-acyl and alkyl fortimicin B derivatives thereof and intermediates therefor

Method of producing 2-deoxyfortimicin A

4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

Antibacterial peptides

6&#39;N-Alkyl- and 6&#39;,6&#39;-di-N-alkyl derivatives of fortimicins A and B

Antibacterial peptide

2-O-Methanesulfonylfortimicin B

(1,2&#39;,6&#39;-Tri-N-(2-O-methanesulfonylsalicylidine)-4,5-(2-O-methanesulfonylsalicylaldehyde) oxazolidine-2-O-methanesulfonylfortimicin B

1,2-Carbamates of fortimicin B and derivatives

1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate

4-N-Acylfortimicin B-1,5-carbamates

1,5-Carbamates of fortimicin B and derivatives

6&#39;-Modified fortimicin compounds

2-Epi-fortimicin A and derivatives

4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture

1,2-Modified fortimicins A and B, intermediates therefor and method for their manufacture

4,5-Carbamates of fortimicin B

2'N-Acyl and alkyl-6'-N-alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B

2'N-acyl and alkyl fortimicin B and derivatives, 4,2'-N,N'diacyl and dialkyl fortimicin B derivatives 4-N-acyl-2'-N-alkyl and 4-N-alkyl-2'-N-acyl fortimicin B derivatives

4-N-Acyl, 2'-N-acyl and 4,2'-N,N'-diacylfortimicin E derivatives

2-Deoxy-2'-N-acyl and alkyl fortimicins A and B

4-N, 2'-N and 4,2'Di-N-fortimicins AH and AI

4-N,2'-N and 4,2'-Di-N-fortimicin AO derivatives

6'-Epi-fortimicin A and B derivatives

4-N, 2'-N and 4,2'-Di-N-fortimicin AL derivatives

6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B

(1,2',6'-Tri-N-(2-O-methanesulfonylsalicylidine)-4,5-(2-O-methanesulfonylsalicylaldehyde) oxazolidine-2-O-methanesulfonylfortimicin B

6'-Modified fortimicin compounds