P

Inventor

COMINS DANIEL L

US41 patents
⚠️ This page may combine multiple inventors who share the name “COMINS DANIEL L”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

UNIV NORTH CAROLINA STATE

34 patents
US5162532ANov 10, 1992

Intermediates and method of making camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE54 citations96
US6995265B2Feb 7, 2006

Synthesis of nicotine derivatives from nicotine

UNIV NORTH CAROLINA STATE36 citations95
US5321140AJun 14, 1994

Pyridinecarboxaldehyde D-ring intermediates useful for the synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE28 citations92
US5247089ASep 21, 1993

Method of making intermediates useful for the manufacture of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE28 citations92
US5243050ASep 7, 1993

Alkylpyridone DE ring intermediates useful for the manufacture of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE22 citations92
US5200524AApr 6, 1993

Camptothecin intermediates and method of making same

UNIV NORTH CAROLINA STATE29 citations92
US5191082AMar 2, 1993

Camptothecin intermediate and method of making camptothecin intermediates

UNIV NORTH CAROLINA STATE34 citations92
US5475108ADec 12, 1995

Camptothecin intermediates and method of making camptothecin and comptothecin analogs

UNIV NORTH CAROLINA STATE9 citations74
US5459269AOct 17, 1995

14-halo-camptothecins

UNIV NORTH CAROLINA STATE17 citations74
US5315007AMay 24, 1994

Process for making DE ring intermediates for the synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE8 citations74
US5264579ANov 23, 1993

D ring intermediates for the synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE6 citations74
US5254690AOct 19, 1993

Alkoxymethylpyridine d-ring intermediates useful for the synthesis of camptpthecin and camptothecin analogs

UNIV NORTH CAROLINA STATE6 citations74
US5212317AMay 18, 1993

Methods and intermediates for the assymmetric synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE14 citations74
US7132545B2Nov 7, 2006

Synthesis of nicotine derivatives from nicotine

UNIV NORTH CAROLINA STATE9 citations73
US7179917B2Feb 20, 2007

Regioselective halogenation of nicotine and substituted nicotines

UNIV NORTH CAROLINA STATE4 citations71
US7067672B2Jun 27, 2006

Regioselective halogenation of nicotine and substituted nicotines

UNIV NORTH CAROLINA STATE7 citations71
US7304160B2Dec 4, 2007

Regiospecific synthesis of nicotine derivatives

UNIV NORTH CAROLINA STATE4 citations69
US5496952AMar 5, 1996

Method of making asymmetric DE ring intermediates for the synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE2 citations63
US5428166AJun 27, 1995

Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE4 citations63
US5395939AMar 7, 1995

Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

UNIV NORTH CAROLINA STATE4 citations63
US7361768B2Apr 22, 2008

Synthesis of nicotine derivatives from nicotine

UNIV NORTH CAROLINA STATE2 citations62
US7112678B2Sep 26, 2006

Regiospecific synthesis of nicotine derivatives

UNIV NORTH CAROLINA STATE3 citations58
US5262571ANov 16, 1993

Cycloalkyl-based chiral auxiliaries and method making the same

UNIV NORTH CAROLINA STATE4 citations54
US6987189B2Jan 17, 2006

Short synthesis of pyridine-based pharmaceutical intermediates

UNIV NORTH CAROLINA STATE0 citations52
US6855825B2Feb 15, 2005

Short synthesis of pyridine-based pharmaceutical intermediates

UNIV NORTH CAROLINA STATE0 citations52
US6706884B2Mar 16, 2004

Short synthesis of pyridine-based pharmaceutical intermediates

UNIV NORTH CAROLINA STATE0 citations52
US6534656B2Mar 18, 2003

Short synthesis of pyridine-based pharmaceutical intermediates

UNIV NORTH CAROLINA STATE0 citations52
US5486615AJan 23, 1996

Method of making asymmetric DE ring intermediates for the synthesis of camptothecin analogs

UNIV NORTH CAROLINA STATE0 citations52
US5478943ADec 26, 1995

Method of making intermediates for camptothecin and its analogs

UNIV NORTH CAROLINA STATE1 citations52
US7888512B2Feb 15, 2011

Synthesis of nicotine derivatives from nicotine

UNIV NORTH CAROLINA STATE0 citations51
US7553968B2Jun 30, 2009

Synthesis of nicotine derivatives from nicotine

UNIV NORTH CAROLINA STATE0 citations51
US7875724B2Jan 25, 2011

Regiospecific synthesis of nicotine derivatives

UNIV NORTH CAROLINA STATE0 citations48
US7671209B2Mar 2, 2010

Regiospecific synthesis of nicotine derivatives

UNIV NORTH CAROLINA STATE0 citations48
US7820826B2Oct 26, 2010

Synthesis and regioselective substitution of 6-halo-and 6-alkoxy nicotine derivatives

UNIV NORTH CAROLINA STATE0 citations46

OSI PHARM INC

3 patents

GLAXO WELLCOME INC

1 patent

NC STATE UNIVERSITY

1 patent

NORTH CARLINA STATE UNIVERSITY

1 patent

COMINS DANIEL L

1 patent