Inventor

JOUNG J KEITH

US77 patents

⚠️ This page may combine multiple inventors who share the name “JOUNG J KEITH”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

JOUNG J KEITH

MASSACHUSETTS GEN HOSPITAL

Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

Engineered CRISPR-Cas9 nucleases

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases

Increasing specificity for RNA-guided genome editing

Engineered CRISPR-CAS9 nucleases with altered PAM specificity

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

Increasing specificity for RNA-guided genome editing

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-Cas9 nucleases

Engineered CRISPR-CAS9 nucleases with altered PAM specificity

Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)

TAL-Tet1 fusion proteins and methods of use thereof

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Comprehensive in vitro reporting of cleavage events by sequencing (Circle-seq)

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Increasing specificity for RNA-guided genome editing

Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Multiplex guide RNAs

Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq)

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing

Full interrogation of nuclease DSBs and sequencing (find-seq)

Methods of transcription activator like effector assembly

RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Engineered CRISPR-Cas9 nucleases with altered PAM specificity

Variants of CRISPR from Prevotella and Francisella 1 (Cpf1)

Engineered CRISPR-Cas9 nucleases

Tale transcriptional activators

TAL-Tet1 fusion proteins and methods of use thereof

Inducible, tunable, and multiplex human gene regulation using CRISPR-Cpf1

MASSACHUSETTS INST TECHNOLOGY

Methods and compositions for interaction trap assays

Methods and compositions for interaction trap assays

Methods and compositions for interaction trap assays

HARVARD COLLEGE

Interaction trap assay, reagents and uses thereof

Intraction trap assay, reagents and uses thereof

FOX CHASE CANCER CT

Yeast bacterial two-hybrid system and methods of use thereof

UNIV BOSTON

Synthetic transcriptional and epigenetic regulators based on engineered, orthogonal zinc finger proteins