Inventor

ROSSI EDMUND A

US76 patents

⚠️ This page may combine multiple inventors who share the name “ROSSI EDMUND A”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

ROSSI EDMUND A

IBC PHARMACEUTICALS INC

Methods and compositions for generating bioactive assemblies of increased complexity and uses

PEGylation by the dock and lock (DNL) technique

Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses

Methods and compositions for generating bioactive assemblies of increased complexity and uses

Multivalent immunoglobulin-based bioactive assemblies

Stably tethered structures of defined compositions with multiple functions or binding specificities

T-cell redirecting bispecific antibodies for treatment of disease

Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases

Tetrameric cytokines with improved biological activity

Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo

PEGylation by the dock and lock (DNL) technique

Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology

Stably tethered structures of defined compositions with multiple functions or binding specificities

Multivalent immunoglobulin-based bioactive assemblies

Combination therapy for inducing immune response to disease

Disease therapy by inducing immune response to Trop-2 expressing cells

Disease therapy by inducing immune response to Trop-2 expressing cells

Combination therapy for inducing immune response to disease

Disease therapy by inducing immune response to Trop-2 expressing cells

Disease therapy by inducing immune response to Trop-2 expressing cells

Multiple signaling pathways induced by hexvalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases

Combination therapy for inducing immune response to disease

Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors

Tetrameric cytokines with improved biological activity

CHANG CHIEN-HSING

Tetrameric cytokines with improved biological activity

Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases

Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in VIVO

Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology

PEGylation by the dock and lock (DNL) technique

Methods and compositions for generating bioactive assemblies of increased complexity and uses

Multivalent immunoglobulin-based bioactive assemblies

Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses

Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in vivo

Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity

Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses

Methods and compositions for generating bioactive assemblies of increased complexity and uses

IMMUNOMEDICS INC

Stable compositions of high-concentration allotype-selected antibodies for small-volume administration

Mammalian cell lines for increasing longevity and protein yield from a cell culture

Mammalian cell lines for increasing longevity and protein yield from cell culture

Fusion proteins containing recombinant cytotoxic RNAses

Methods and compositions for increasing longevity and protein yield from a cell culture

Stable compositions of high-concentration allotype-selected antibodies for small-volume administration

Stable compositions of high-concentration allotype-selected antibodies for small-volume administration

Therapeutic use of anti-CD22 antibodies for inducing trogocytosis

Therapeutic use of anti-CD22 antibodies for inducing trogocytosis

Ultrafiltration concentration of allotype selected antibodies for small-volume administration

Therapeutic use of anti-CD22 antibodies for inducing trogocytosis

GOLDENBERG DAVID M

Methods and compositions for treatment of human immunodeficiency virus infection with conjugated antibodies or antibody fragments

Mammalian cell lines for increasing longevity and protein yield from a cell culture

ZENG LI

Ultrafiltration concentration of allotype selected antibodies for small-volume administration