Inventor
COOK PHILLIP D
US32 patents
⚠️ This page may combine multiple inventors who share the name “COOK PHILLIP D”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
ISIS PHARMACEUTICALS INC
23 patentsUS5623065AApr 22, 1997
Gapped 2' modified oligonucleotides
ISIS PHARMACEUTICALS INC662 citations99
US5607923AMar 4, 1997
Oligonucleotides for modulating cytomegalovirus having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC136 citations99
US5599797AFeb 4, 1997
Oligonucleotides having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC248 citations99
US5587361ADec 24, 1996
Oligonucleotides having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC1,412 citations99
US5587469ADec 24, 1996
Oligonucleotides containing N-2 substituted purines
ISIS PHARMACEUTICALS INC1,440 citations99
US5578718ANov 26, 1996
Thiol-derivatized nucleosides
ISIS PHARMACEUTICALS INC1,007 citations99
US5576302ANov 19, 1996
Oligonucleotides for modulating hepatitis C virus having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC255 citations99
US5521302AMay 28, 1996
Process for preparing oligonucleotides having chiral phosphorus linkages
ISIS PHARMACEUTICALS INC243 citations99
US5359044AOct 25, 1994
Cyclobutyl oligonucleotide surrogates
ISIS PHARMACEUTICALS INC1,216 citations99
US5212295AMay 18, 1993
Monomers for preparation of oligonucleotides having chiral phosphorus linkages
ISIS PHARMACEUTICALS INC389 citations99
US5637684AJun 10, 1997
Phosphoramidate and phosphorothioamidate oligomeric compounds
ISIS PHARMACEUTICALS INC561 citations98
US5614621AMar 25, 1997
Process for preparing oligonucleotides using silyl-containing diamino phosphorous reagents
ISIS PHARMACEUTICALS INC116 citations98
US5587471ADec 24, 1996
Method of making oligonucleotide libraries
ISIS PHARMACEUTICALS INC108 citations98
US5539083AJul 23, 1996
Peptide nucleic acid combinatorial libraries and improved methods of synthesis
ISIS PHARMACEUTICALS INC782 citations98
US5506212AApr 9, 1996
Oligonucleotides with substantially chirally pure phosphorothioate linkages
ISIS PHARMACEUTICALS INC125 citations98
US5514786AMay 7, 1996
Compositions for inhibiting RNA activity
ISIS PHARMACEUTICALS INC108 citations97
US5635488AJun 3, 1997
Compounds having phosphorodithioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC92 citations96
US5620963AApr 15, 1997
Oligonucleotides for modulating protein kinase C having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC80 citations96
US5543507AAug 6, 1996
Covalently cross-linked oligonucleotides
ISIS PHARMACEUTICALS INC92 citations96
US5359051AOct 25, 1994
Compounds useful in the synthesis of nucleic acids capable of cleaning RNA
ISIS PHARMACEUTICALS INC59 citations95
US5632898AMay 27, 1997
Method for removing unreacted electrophiles from a reaction mixture
ISIS PHARMACEUTICALS INC22 citations92
US5459243AOct 17, 1995
Apparatus and processes for the large scale generation and transfer of diazomethane
ISIS PHARMACEUTICALS INC34 citations92
US6448373B1Sep 10, 2002
Phosphate linked oligomers formed of monomeric diols and processes for preparing same
ISIS PHARMACEUTICALS INC6 citations59
WARNER LAMBERT CO
6 patentsUS4826823AMay 2, 1989
Methods of using 2-chloro-2'-deoxyadenosine-5'-phosphate and its salts
WARNER LAMBERT CO38 citations92
US4719295AJan 12, 1988
Compound 2-iodo-2'-deoxyadenosine
WARNER LAMBERT CO14 citations73
US4908441AMar 13, 1990
Deoxyadenosine compounds and methods of making and using the same
WARNER LAMBERT CO5 citations62
US4681873AJul 21, 1987
4-amino-3-halo-2-pyridinone nucleoside and nucleotide compounds
WARNER LAMBERT CO4 citations62
US4503235AMar 5, 1985
Process for producing 4-carbamoyl-1H-imidazolium-5-olate
WARNER LAMBERT CO3 citations62
US4801698AJan 31, 1989
Process for preparing diaminopyrimido(4,5-d)pyrimidine glycoside and glycotide
WARNER LAMBERT CO1 citations52