Inventor

WOLTERSDORF JR OTTO W

65 patents

Patents

50 patents

US4751244AJun 14, 1988

3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-triazin-2-yl)2-pyrazinecarboxamides

MERCK & CO INC50 citations96

US4296122AOct 20, 1981

2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids

MERCK & CO INC59 citations96

US4140776AFeb 20, 1979

N-pyrazinecarbonyl-N'-acylguanidines

MERCK & CO INC52 citations96

US4096267AJun 20, 1978

(1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof

MERCK & CO INC55 citations96

US4087542AMay 2, 1978

2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids

MERCK & CO INC59 citations96

US4085117AApr 18, 1978

6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids

MERCK & CO INC56 citations96

US4085219AApr 18, 1978

1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids

MERCK & CO INC55 citations96

US4070539AJan 24, 1978

[1-Oxo-2-halo(or hydrogen) indanyloxy]-alkanoic acid

MERCK & CO INC56 citations96

US4012524AMar 15, 1977

[1-Hydroxy-5-indanyloxy (or thio)]-alkanoic acids

MERCK & CO INC63 citations96

US4006180AFeb 1, 1977

[1,3-Dihydroxy-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids

MERCK & CO INC59 citations96

US3984465AOct 5, 1976

1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids

MERCK & CO INC58 citations96

US3953476AApr 27, 1976

3-Amino-5-sulfonylbenzoic acids

MERCK & CO INC62 citations96

US3931239AJan 6, 1976

6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids

MERCK & CO INC58 citations96

US4246406AJan 20, 1981

Heterocyclic substituted pyrazinoylguanidines

MERCK & CO INC60 citations95

US4085211AApr 18, 1978

Pyrazinecarboxamides and processes for preparing same

MERCK & CO INC81 citations95

US4775695AOct 4, 1988

Substituted amidinoalkoxy and amidinoalkylamino indanones and salts thereof

MERCK & CO INC27 citations93

US4654365AMar 31, 1987

2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury

MERCK & CO INC32 citations93

US4634717AJan 6, 1987

Substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones, useful for treating persons with gray matter edema

MERCK & CO INC32 citations93

US4605664AAug 12, 1986

Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treatment of grey matter edema

MERCK & CO INC27 citations93

US4605663AAug 12, 1986

Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones, for treatment of grey matter edema

MERCK & CO INC26 citations93

US4604403AAug 5, 1986

Use of substituted-3(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treating grey matter edema

MERCK & CO INC26 citations93

US4604396AAug 5, 1986

[(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimidamides and [(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimidic acid hydrazides, their derivatives and their salts

MERCK & CO INC32 citations93

US4596821AJun 24, 1986

Treatment of gray matter edema with 3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones

MERCK & CO INC28 citations93

US4579869AApr 1, 1986

Substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic acids, their derivatives and their salts

MERCK & CO INC39 citations93

US4465850AAug 14, 1984

Treatment of brain injury due to gray matter edema with (indanyloxy) butanoic acids

MERCK & CO INC38 citations93

US4426388AJan 17, 1984

5-Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure

MERCK & CO INC51 citations93

US4416890ANov 22, 1983

Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure

MERCK & CO INC46 citations93

US4401669AAug 30, 1983

2,3-Dihydro-substituted-5-benzoyl benzofuran-2-carboxylic acids and their use in treating hypertension

MERCK & CO INC45 citations93

US4291050ASep 22, 1981

6,7-Disubstituted-2 or 2,2-substituted-5-substituted-1-indanones

MERCK & CO INC47 citations93

US4272537AJun 9, 1981

3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides

MERCK & CO INC35 citations93

US4249021AFeb 3, 1981

Indanacetic acid compounds

MERCK & CO INC35 citations93

US4145551AMar 20, 1979

Pyrazine-2-carbonyloxyguanidines

MERCK & CO INC49 citations93

US4087526AMay 2, 1978

(3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens

MERCK & CO INC51 citations93

US4081554AMar 28, 1978

1-oxo-2,2-disubstituted-5-indanyloxy(or thio)alkano acids

MERCK & CO INC36 citations93

US3984552AOct 5, 1976

6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids

MERCK & CO INC47 citations93

US3976686AAug 24, 1976

[1-Oxo-2,3-hydrocarbylene-5-indanyloxy(or thio)]alkanoic acids

MERCK & CO INC43 citations93

US3976681AAug 24, 1976

[1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids

MERCK & CO INC41 citations93

US3974212AAug 10, 1976

[1-Hydroximino-2,2-disubstituted-5-indanyloxy-(or thio)]alkanoic acids

MERCK & CO INC51 citations93

US3966966AJun 29, 1976

Pharmaceutical compositions and method of treatment employing 1,3-dioxo-2,2-disubstituted indanyloxy alkanoic acids

MERCK & CO INC46 citations93

US4835313AMay 30, 1989

(5,6-dichloro-3-oxo-9α-propyl-2,3,9,9α-tetrahydrofluoren-7-yl) alkanimidamides

MERCK & CO INC31 citations92

US4797391AJan 10, 1989

((5,6-dichloro-3-oxo-9,9a-disubstituted-2,3,9,9a-tetrahydrofluoren-7-yl)oxy)alkanoic acids and alkanimidamides

MERCK & CO INC37 citations92

US4731470AMar 15, 1988

[(5,6-dichloro-3-oxo-2,9a-alkano-2,3,9,9a-tetrahydro-1H-fluoren-7-yl)oxy]alkanoic acids and alkanimidamides

MERCK & CO INC42 citations92

US4731471AMar 15, 1988

(5,6-dichloro-3-oxo-2,3,9,9a-tetrahydrofluoren-7-yl)-alkanoic acids and alkanimidamides bearing novel functional 9a-substituents

MERCK & CO INC41 citations92

US4731472AMar 15, 1988

(5,6-dichloro-3-oxo-9A-propyl-2,3,9,9A-tetrahydrofluoren-7-yl)alkanoic acids and alkanimidamides

MERCK & CO INC47 citations92

US4719310AJan 12, 1988

Ester and amide substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy)alkanoic acids and their salts

MERCK & CO INC31 citations92

US4100294AJul 11, 1978

5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives

MERCK & CO INC47 citations92

Showing the top 50 of 65 patents by PatentIndex Score.

WOLTERSDORF JR OTTO W

Patents

Compounds useful in treating sickle cell anemia

Method of treating a person for sickle cell anemia

Compounds useful in treating sickle cell anemia

Compounds useful in treating sickle cell anemia

3-Amino-5-substituted-6-halo-N-(3,4-dihydro-6-substituted-1,3,5-triazin-2-yl)2-pyrazinecarboxamides

2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids

N-pyrazinecarbonyl-N&#39;-acylguanidines

(1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio) alkanoic acids, and derivatives thereof

2,3-Dihydro-6,7-disubstituted-5-acyl benzofuran-2-carboxylic acids

6,7-Disubstituted-5-(acyl)benzofuran-2-carboxylic acids

1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids

[1-Oxo-2-halo(or hydrogen) indanyloxy]-alkanoic acid

[1-Hydroxy-5-indanyloxy (or thio)]-alkanoic acids

[1,3-Dihydroxy-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids

1-Oxo-2,2-disubstituted-5-indanyloxy(or thio)alkanoic acids

3-Amino-5-sulfonylbenzoic acids

6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids

Heterocyclic substituted pyrazinoylguanidines

Pyrazinecarboxamides and processes for preparing same

Substituted amidinoalkoxy and amidinoalkylamino indanones and salts thereof

2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury

Substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones, useful for treating persons with gray matter edema

Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treatment of grey matter edema

Use of substituted-3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones, for treatment of grey matter edema

Use of substituted-3(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones for treating grey matter edema

[(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimidamides and [(2,3,9,9a-tetrahydro-3-oxo-9a-substituted-1H-fluoren-7-yl)oxy]ethanimidic acid hydrazides, their derivatives and their salts

Treatment of gray matter edema with 3-(2,3-dihydro-1H-inden-5-yl)-4-hydroxy-1H-pyrrole-2,5-diones

Substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic acids, their derivatives and their salts

Treatment of brain injury due to gray matter edema with (indanyloxy) butanoic acids

5-Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure

Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure

2,3-Dihydro-substituted-5-benzoyl benzofuran-2-carboxylic acids and their use in treating hypertension

6,7-Disubstituted-2 or 2,2-substituted-5-substituted-1-indanones

3-Amino-5-substituted-6-halo-N-(4,4-disubstituted-6-substituted-1,3,5-triazin-2-yl)-2-pyrazinecarboxamides

Indanacetic acid compounds

Pyrazine-2-carbonyloxyguanidines

(3-Amino-5-substituted-6-fluoropyrazinoyl or pyrazamido)-guanidines and their derivatives bearing substituents on the guanidino nitrogens

1-oxo-2,2-disubstituted-5-indanyloxy(or thio)alkano acids

6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids

[1-Oxo-2,3-hydrocarbylene-5-indanyloxy(or thio)]alkanoic acids

[1,3-Dioxo-2-substituted and 2,2-disubstituted- indanyloxy (or thio] alkanoic acids

[1-Hydroximino-2,2-disubstituted-5-indanyloxy-(or thio)]alkanoic acids

Pharmaceutical compositions and method of treatment employing 1,3-dioxo-2,2-disubstituted indanyloxy alkanoic acids

(5,6-dichloro-3-oxo-9α-propyl-2,3,9,9α-tetrahydrofluoren-7-yl) alkanimidamides

((5,6-dichloro-3-oxo-9,9a-disubstituted-2,3,9,9a-tetrahydrofluoren-7-yl)oxy)alkanoic acids and alkanimidamides

[(5,6-dichloro-3-oxo-2,9a-alkano-2,3,9,9a-tetrahydro-1H-fluoren-7-yl)oxy]alkanoic acids and alkanimidamides

(5,6-dichloro-3-oxo-2,3,9,9a-tetrahydrofluoren-7-yl)-alkanoic acids and alkanimidamides bearing novel functional 9a-substituents

(5,6-dichloro-3-oxo-9A-propyl-2,3,9,9A-tetrahydrofluoren-7-yl)alkanoic acids and alkanimidamides

Ester and amide substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy)alkanoic acids and their salts

5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives

N-pyrazinecarbonyl-N'-acylguanidines