Inventor
JOHN VARGHESE
US90 patents
⚠️ This page may combine multiple inventors who share the name “JOHN VARGHESE”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
ELAN PHARM INC
25 patentsUS6627739B1Sep 30, 2003
β-secretase enzyme compositions and methods
ELAN PHARM INC48 citations95
US7252963B2Aug 7, 2007
β-secretase enzyme compositions and methods
ELAN PHARM INC10 citations92
US7115410B1Oct 3, 2006
β-secretase enzyme compositions and methods
ELAN PHARM INC16 citations92
US7109017B1Sep 19, 2006
β-secretase enzyme compositions and methods
ELAN PHARM INC13 citations92
US7034182B2Apr 25, 2006
Compounds to treat Alzheimer's disease
ELAN PHARM INC37 citations92
US6982264B2Jan 3, 2006
Substituted alcohols useful in treatment of Alzheimer's disease
ELAN PHARM INC38 citations92
US6211235B1Apr 3, 2001
Compounds for inhibiting β-amyloid peptide release and/or its synthesis
ELAN PHARM INC46 citations92
US5994398ANov 30, 1999
Arylsulfonamides as phospholipase A2 inhibitors
ELAN PHARM INC27 citations92
US7727997B2Jun 1, 2010
N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
ELAN PHARM INC21 citations89
US7223774B2May 29, 2007
Benzamide 2-hydroxy-3-diaminoalkanes
ELAN PHARM INC34 citations89
US7514408B1Apr 7, 2009
β-secretase enzyme compositions and methods
ELAN PHARM INC10 citations84
US6207710B1Mar 27, 2001
Compounds for inhibiting β-amyloid peptide release and/or its synthesis
ELAN PHARM INC22 citations84
US7544717B2Jun 9, 2009
2-amino- and 2-thio- substituted 1,3-diaminopropanes
ELAN PHARM INC9 citations83
US7456007B1Nov 25, 2008
β-secretase enzyme compositions and methods
ELAN PHARM INC10 citations83
US7214715B2May 8, 2007
Compounds to treat Alzheimer's disease
ELAN PHARM INC18 citations83
US7067271B1Jun 27, 2006
β-secretase enzyme compositions and methods
ELAN PHARM INC12 citations83
US7030239B2Apr 18, 2006
Compounds to treat Alzheimer's disease
ELAN PHARM INC13 citations83
US6992081B2Jan 31, 2006
Compounds to treat Alzheimer's disease
ELAN PHARM INC13 citations83
US6737420B2May 18, 2004
Compounds to treat Alzheimer's disease
ELAN PHARM INC14 citations83
US7276349B2Oct 2, 2007
Beta-secretase enzyme compositions and methods
ELAN PHARM INC9 citations73
US7262043B2Aug 28, 2007
β-secretase enzyme compositions and methods
ELAN PHARM INC9 citations73
US6476263B1Nov 5, 2002
Compounds for inhibiting β-amyloid peptide release and/or its synthesis
ELAN PHARM INC5 citations63
US6861558B2Mar 1, 2005
Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis
ELAN PHARM INC2 citations62
US6518424B1Feb 11, 2003
Substituted pyrimidine compositions and methods of use
ELAN PHARM INC6 citations62
US7119085B2Oct 10, 2006
Methods to treat alzheimer's disease
ELAN PHARM INC2 citations61
ATHENA NEUROSCIENCES INC
11 patentsUS6653303B1Nov 25, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC16 citations92
US6544978B2Apr 8, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC16 citations92
US6117901ASep 12, 2000
N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use
ATHENA NEUROSCIENCES INC18 citations92
US6096782AAug 1, 2000
N-(aryl/heteroaryl) amino acid derivatives pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC18 citations92
US6541466B2Apr 1, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC10 citations82
US5965614AOct 12, 1999
N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC6 citations74
US6635632B1Oct 21, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC6 citations73
US6399628B1Jun 4, 2002
N-(aryl/heteroaryl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting alpha- amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC2 citations63
US6667305B1Dec 23, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC1 citations62
US6632811B2Oct 14, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC1 citations62
US6559141B2May 6, 2003
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
ATHENA NEUROSCIENCES INC2 citations62
BUCK INST RES AGING
6 patentsUS10202355B2Feb 12, 2019
Hydantoins that modulate bace-mediated app processing
BUCK INST RES AGING4 citations84
US9926280B2Mar 27, 2018
Hydantoins that modulate BACE-mediated APP processing
BUCK INST RES AGING4 citations84
US10835546B2Nov 17, 2020
App specific BACE inhibitors (ASBIs) and uses thereof
BUCK INST RES AGING1 citations73
US10357508B2Jul 23, 2019
APP specific BACE inhibitors (ASBIs) and uses thereof
BUCK INST RES AGING2 citations73
USRE49873EMar 19, 2024
APP specific bace inhibitors (ASBIs) and uses thereof
BUCK INST RES AGING0 citations62
US11091444B2Aug 17, 2021
Hydantoins that modulate BACE-mediated app processing
BUCK INST RES AGING0 citations62
UPJOHN CO
4 patentsUS7176242B2Feb 13, 2007
N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives
UPJOHN CO92 citations95
US7244725B2Jul 17, 2007
Acetyl 2-hydroxy-1, 3-diaminoalkanes
UPJOHN CO16 citations83
US6846813B2Jan 25, 2005
Compounds to treat alzheimer's disease
UPJOHN CO10 citations73
US7338965B2Mar 4, 2008
3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines
UPJOHN CO4 citations62
LILLY CO ELI
2 patents(unassigned)
1 patentUNIV CALIFORNIA
1 patentShowing the top 50 of 90 patents by PatentIndex Score.