Inventor
BERNETT MATTHEW
US48 patents
⚠️ This page may combine multiple inventors who share the name “BERNETT MATTHEW”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
XENCOR INC
42 patentsUS9650446B2May 16, 2017
Heterodimeric proteins
XENCOR INC44 citations98
US10793632B2Oct 6, 2020
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
XENCOR INC22 citations94
US10787518B2Sep 29, 2020
Bispecific checkpoint inhibitor antibodies
XENCOR INC15 citations94
US10550185B2Feb 4, 2020
Bispecific heterodimeric fusion proteins containing IL-15-IL-15Rα Fc-fusion proteins and PD-1 antibody fragments
XENCOR INC29 citations94
US10501543B2Dec 10, 2019
IL15/IL15Rα heterodimeric Fc-fusion proteins
XENCOR INC13 citations92
US10227411B2Mar 12, 2019
Modulation of T cells with bispecific antibodies and FC fusions
XENCOR INC17 citations92
US9822186B2Nov 21, 2017
Bispecific antibodies that bind to CD38 and CD3
XENCOR INC17 citations92
US11377477B2Jul 5, 2022
PD-1 targeted IL-15/IL-15RALPHA fc fusion proteins and uses in combination therapies thereof
XENCOR INC7 citations85
US11358999B2Jun 14, 2022
IL-12 heterodimeric Fc-fusion proteins
XENCOR INC12 citations85
US11319355B2May 3, 2022
Engineered IL-2 Fc fusion proteins
XENCOR INC5 citations84
US11053316B2Jul 6, 2021
Optimized antibody variable regions
XENCOR INC7 citations84
US10981992B2Apr 20, 2021
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
XENCOR INC6 citations84
US10858417B2Dec 8, 2020
Heterodimeric proteins
XENCOR INC7 citations84
US10738133B2Aug 11, 2020
Heterodimeric proteins
XENCOR INC9 citations84
US10131710B2Nov 20, 2018
Optimized antibody variable regions
XENCOR INC15 citations84
US10106624B2Oct 23, 2018
Heterodimeric proteins
XENCOR INC7 citations84
US12239688B2Mar 4, 2025
IL-15/IL-15RA heterodimeric Fc fusion proteins and uses thereof
XENCOR INC2 citations75
US11634506B2Apr 25, 2023
Heterodimeric proteins
XENCOR INC2 citations73
US11584794B2Feb 21, 2023
Bispecific heterodimeric fusion proteins containing IL-15-IL-15Ralpha Fc-fusion proteins and immune checkpoint antibody fragments
XENCOR INC2 citations73
US11524991B2Dec 13, 2022
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
XENCOR INC5 citations73
US11236170B2Feb 1, 2022
Bispecific checkpoint inhibitor antibodies
XENCOR INC1 citations73
US10968276B2Apr 6, 2021
Optimized anti-CD3 variable regions
XENCOR INC6 citations73
US11851466B2Dec 26, 2023
Targeted IL-12 heterodimeric Fc-fusion proteins
XENCOR INC3 citations72
US11655277B2May 23, 2023
IL-12 heterodimeric Fc-fusion proteins
XENCOR INC2 citations72
US12415849B2Sep 16, 2025
Heterodimeric proteins
XENCOR INC0 citations63
US11814423B2Nov 14, 2023
Heterodimeric proteins
XENCOR INC0 citations63
US11718667B2Aug 8, 2023
Optimized antibody variable regions
XENCOR INC0 citations63
US10487155B2Nov 26, 2019
Heterodimeric proteins
XENCOR INC1 citations63
US12378313B2Aug 5, 2025
Bispecific binding agents binding to CLDN18.2 and CD3
XENCOR INC0 citations62
US12359002B2Jul 15, 2025
Heterodimeric antibodies that bind CD3 and tumor antigens
XENCOR INC0 citations62
US12234270B2Feb 25, 2025
IL-12 heterodimeric Fc-fusion proteins
XENCOR INC0 citations62
US12152076B2Nov 26, 2024
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
XENCOR INC0 citations62
US12129309B2Oct 29, 2024
Heterodimeric antibodies that bind CD3 and CD38
XENCOR INC0 citations62
US12006345B2Jun 11, 2024
Untargeted and targeted IL-10 Fc-fusion proteins
XENCOR INC0 citations62
US11981717B2May 14, 2024
Engineered IL-2 Fc fusion proteins
XENCOR INC0 citations62
US11840579B2Dec 12, 2023
Bispecific antibodies that bind to CD38 and CD3
XENCOR INC0 citations62
US11312770B2Apr 26, 2022
Bispecific and monospecific antibodies using novel anti-PD-1 sequences
XENCOR INC1 citations62
US11492407B2Nov 8, 2022
Bispecific checkpoint inhibitor antibodies
XENCOR INC0 citations61
US11091548B2Aug 17, 2021
Modulation of T cells with bispecific antibodies and Fc fusions
XENCOR INC0 citations60
US10544187B2Jan 28, 2020
Targeting regulatory T cells with heterodimeric proteins
XENCOR INC1 citations59
US10472427B2Nov 12, 2019
Heterodimeric proteins
XENCOR INC0 citations52
US10519242B2Dec 31, 2019
Targeting regulatory T cells with heterodimeric proteins
XENCOR INC0 citations48