Inventor

USKOKOVIC MILAN R

US74 patents

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USKOKOVIC MILAN R

HOFFMANN LA ROCHE

Administration of biologically active vitamin D3 and vitamin D2 materials

Administration of biologically active vitamin D3 and vitamin D2 materials

Method of treating hyperproliferative skin diseases with fluorinated vitamin D3 analogs

Vitamin D compounds

Vitamin D3 Flourinated Analogs

Vitamin D3 analogs

Synthesis of 1α,25-dihydroxyergocalciferol

Vitamin D3 analogs

Method for inhibiting hyperproliferative diseases

Vitamin D3 fluorinated analogs

Trihydroxy-cholecacliferol and trihydroxy-ergocalciferol for treating leukemia

Process for the synthesis of 1α,23(S),25-trihydroxycholecalciferol and 1α,23(R),25-trihydroxycholecalciferol

Novel thiophene derivatives

Novel thiophene derivatives

Methods of treatment

25,26-dehydro-1α,24R-dihydroxycholecalciferol and 25,26-dehydro-1α,24S-dihydroxycholecalciferol and the epimeric mixture

Deuterated analogs of 1,25-dihydroxycholecalciferol

25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers

Process and intermediates for the synthesis of vitamin D3 metabolites

8-Methoxypsoralen derivatives

Process for chenodeoxycholic acid and intermediates therefore

Synthesis of 1α,25-dihydroxy-24R-fluorocholecalciferol and 1α,25-dihydroxy-24S-fluorocholecalciferol

Synthesis of 1α,25-dihydroxy-24R-fluorocholecalciferol and 1α,25-dihydroxy-24S-fluorocholecalciferol

Process for the preparation of 24,24-difluoro-1α,25-dihydroxy vitamin D3 and intermediates obtained therefrom

Vitamin D3 metabolite derivatives

1α-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol

Deuterated analogs of 1,25-dihydroxycholecalciferol

Deuterated analogs of 1,25-dihydroxycholecalciferol

Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds

Method of treating disease states by the administration of 1α,25,26-trihydroxycholecalciferol

Synthesis of 1α,25-dihydroxyergocalciferol

Method of treatment

Process and intermediates for the synthesis of Vitamin D3 metabolites and chenodeoxycholic acid

Biotin intermediates

Vitamin D3 fluorinated analogs

25, 28-dihydroxyergocalciferol and 1,25,28-trihydroxyergocalciferol compositions thereof and their use in the treatment of hyperproliferative disease

Process for chenodeoxycholic acid production

Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol

Antipsoriatic agents

Process for the preparation of 1α,23,25-trihydroxycholecalciferol-26-oic acid 23,26-lactone

Method of treating milk fever

Chiral synthesis of amino sugars

Chiral synthesis of amino sugars

Intermediate racemates for the preparation of biotin and a process for their preparation

Hexahydro thieno imadazole intermediates for the synthesis of biotin

Isoxazolines and isoxazolidines

Preparation of biotin

Steroid intermediates for the formation of vitamin D3 analogues

Synthesis of biotin

SYNTEX INC

Fluorinated vitamin D3 analogs