Inventor

SHARPE ARLENE H

US22 patents

⚠️ This page may combine multiple inventors who share the name “SHARPE ARLENE H”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

SHARPE ARLENE H

DANA FARBER CANCER INST INC

Methods of identifying compounds that upmodulate T cell activation in the presence of a PD-1 mediated signal

Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use

Agents that modulate the interaction of B7-1 polypeptide with PD-L1 and methods of use thereof

Nucleic acid molecules encoding B7-1

Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use

Anti-PD-L1 monoclonal antibodies and fragments thereof

Agents that modulate immune cell activation and methods of use thereof

Methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors

Agents that modulate immune cell activation and methods of use thereof

Compositions and methods for identification, assessment, prevention, and treatment of T-cell exhaustion using CD39 biomarkers and modulators

Method of assessing the efficacy of a test agent for modulating programmed death 1 (PD-1) signaling by using anti-phosphotyrosinylated PD-1 monoclonal antibodies

Anti-phosphotyrosinylated programmed death 1 (PD-1) monoclonal antibodies, methods of making and methods of using thereof

Methods and compositions for perturbing gene expression in hematopoietic stem cell lineages in vivo

HARVARD COLLEGE

Compositions and methods for modulating an immune response

Regulatory T cell PD-1 modulation for regulating T cell effector immune responses

Compositions and methods for modulating an immune response

Compositions and methods for modulating an immune response

BRIGHAM & WOMENS HOSPITAL

B7-specific antibodies

T cell costimulatory polypeptides containing alternative domains

DANA FARBER CANCER INST BRIGHA

Nucleic acids encoding B7-1 and B7-2 molecules

BRIGHAM & WOMAN S HOSPITAL

B7-1 and B7-2 polypeptides

CHILDRENS MEDICAL CENTER

Methods of treating cancer using LSD1 inhibitors in combination with immunotherapy