Inventor

COOK PHILLIP DAN

US164 patents

⚠️ This page may combine multiple inventors who share the name “COOK PHILLIP DAN”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

COOK PHILLIP DAN

ISIS PHARMACEUTICALS INC

Oligonucleolotides having site specific chiral phosphorothioate internucleoside linkages

Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase

Amine-derivatized nucleosides and oligonucleosides

Gapped oligonucleotides

Amine-derivatized nucleosides and oligonucleosides

Amine-derivatized nucleosides and oligonucleosides

Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom

2′-O-aminoethyloxyethyl-modified oligonucleotides

Guanidinium functionalized oligonucleotides and method/synthesis

Oligonucleotide-folate conjugates

Sugar-modified gapped oligonucleotides

Sugar modified oligonucleotides

Derivatized oligonucleotides having improved uptake and other properties

Nucleosidic and non-nucleosidic folate conjugates

Gapped 2′ modified oligonucleotides

PNA-DNA-PNA chimeric macromolecules

Phosphorothioate oligonucleotides having modified internucleoside linkages

Oligonucleotides having chiral phosphorus linkages

Aminooxy-modified oligonucleotides and methods for making same

N-2 substituted purines

Derivatized oligonucleotides having improved uptake and other properties

2&#39;-O-aminooxy-modified oligonucleotides

2&#39;-O-modified nucleosides and phosphoramidites

N-2 substituted purines in oligonucleotides

Heteroatomic oligonucleoside linkages

PNA-DNA-PNA chimeric macromolecules

Methods of making conjugated 4&#39; desmethyl nucleoside analog compounds

Substituted purines and oligonucleotide cross-linking

Heteroatomic oligonucleoside linkages

Oligonucleotides for modulating Ha-ras or Ki-ras having phosphorothioate linkages of high chiral purity

Heteroatomic oligonucleoside linkages

Conjugated 4&#39;-desmethyl nucleoside analog compounds

Antisense oligonucleotide inhibition of the RAS gene

Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms

Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling

Backbone modified oligonucleotide analogs

4&#39;-desmethyl nucleoside analog compounds

Polyamine conjugated oligonucleotides

Polyamine conjugated oligonucleotides

Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase

Oligonucleotides containing 2′-O-modified purines

Nucleosidic and non-nucleosidic folate conjugates

Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals

Compositions and methods for non-parenteral delivery of oligonucleotides

2&#39;modified oligonucleotides

Oligonucleotides having site specific chiral phosphorothioate internucleoside linkages

Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefrom

MERCK & CO INC

Thionucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase

Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase

Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase of hepatitis C virus

2'-O-aminooxy-modified oligonucleotides

2'-O-modified nucleosides and phosphoramidites

Methods of making conjugated 4' desmethyl nucleoside analog compounds

Conjugated 4'-desmethyl nucleoside analog compounds

4'-desmethyl nucleoside analog compounds

2'modified oligonucleotides