Inventor

VERHOEVEN THOMAS R

US35 patents

⚠️ This page may combine multiple inventors who share the name “VERHOEVEN THOMAS R”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

VERHOEVEN THOMAS R

MERCK & CO INC

Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof

Process for C-methylation of 2-methylbutyrates

Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein

Process of synthesizing binaphthyl derivatives

Triazolylmethyl-indole ethylamine bisulfate salt

Process for preparing HMG-CoA reductase inhibitors with a 3,5-dihydroxypentanoate subunit

Process for the preparation of biphenyl intermediates

Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

Ruthenium-phosphine complex catalysts for asymmetric hydrogenations

Palladium catalyzed ring closure of triazolyltryptamine

Process for the preparation of imidazolutidine

Asymmetric hydrogenation of beta- or gamma-ketoesters and beta- or gamma-ketoamides

Process of synthesizing binaphthyl derivatives

Regiospecific process to make cis-1-amino-2-alkanol from epoxide

Process for the preparation of diisopinocampheylchloroborane

In-situ preparation of diisopinocamphenyl chloroborane

Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps

Process for the formation of 6-desmethyl-6-exo-methylene derivatives of lovastatin and analogs thereof

Acylation process for the synthesis of HMG-CoA reductase inhibitors

Process for the preparation of HMG-CoA reductase inhibitors

Deblocking process for allyl esters with regeneratable polymer supported Pd(O)

Process for the preparation of diisopinocampheylchloroborane

Quantitative conversion of indene to (1S,2R) indene oxide and (1S,2R)-indandiol by combination of haloperoxidase bioconversion and chemical steps

Hydrogenation process for the formation of 4A,5-dihydro HMG-CoA reductase inhibitors

Hydrogenation process for the formation of 3,4-dihydro HMG-CoA reductase inhibitors

Preparation of dibenzo[b,f]thiepin compounds

Regiospecific processes to make cis-1-amino-2-alkanol from diol

Process of making spirocycles and analogs thereof

Hydrogenation process for the formation of tetrahydro HMG-CoA reductase inhibitors

Hydrogenation process for the formation of 3,5-dihydro HMG-CoA reductase inhibitors

Polymorphic forms of an angiotensin II antagonist

Process of making 2,5-diaryl tetrahydrofurans and analogs thereof useful as PAF antagonists

MARCK & CO INC

Regiospecific processes to make CIS-1-Amino-2-Alkanol from Diol or Halohydrin

MERCK FROSST CANADA INC

Stereoselective synthesis of leukotriene antagonists

WISCONSIN ALUMNI RES FOUND

Catalytic allylic alkylation