Inventor
MONIA BRETT P
US141 patents
⚠️ This page may combine multiple inventors who share the name “MONIA BRETT P”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
ISIS PHARMACEUTICALS INC
44 patentsUS7732590B2Jun 8, 2010
Modulation of diacylglycerol acyltransferase 2 expression
ISIS PHARMACEUTICALS INC132 citations99
US7015315B1Mar 21, 2006
Gapped oligonucleotides
ISIS PHARMACEUTICALS INC409 citations99
US6451991B1Sep 17, 2002
Sugar-modified gapped oligonucleotides
ISIS PHARMACEUTICALS INC244 citations99
US6326199B1Dec 4, 2001
Gapped 2′ modified oligonucleotides
ISIS PHARMACEUTICALS INC282 citations99
US6100090AAug 8, 2000
Antisense inhibition of PI3K p85 expression
ISIS PHARMACEUTICALS INC137 citations99
US6033910AMar 7, 2000
Antisense inhibition of MAP kinase kinase 6 expression
ISIS PHARMACEUTICALS INC176 citations99
US5958773ASep 28, 1999
Antisense modulation of AKT-1 expression
ISIS PHARMACEUTICALS INC202 citations99
US5623065AApr 22, 1997
Gapped 2' modified oligonucleotides
ISIS PHARMACEUTICALS INC662 citations99
US5576208ANov 19, 1996
Antisense oligonucleotide inhibition of the RAS gene
ISIS PHARMACEUTICALS INC151 citations99
US7563884B2Jul 21, 2009
Antisense modulation of PTP1B expression
ISIS PHARMACEUTICALS INC67 citations98
US6391636B1May 21, 2002
Antisense oligonucleotide modulation of raf gene expression
ISIS PHARMACEUTICALS INC89 citations98
US6287860B1Sep 11, 2001
Antisense inhibition of MEKK2 expression
ISIS PHARMACEUTICALS INC334 citations98
US6210892B1Apr 3, 2001
Alteration of cellular behavior by antisense modulation of mRNA processing
ISIS PHARMACEUTICALS INC358 citations98
US6172216B1Jan 9, 2001
Antisense modulation of BCL-X expression
ISIS PHARMACEUTICALS INC399 citations98
US6046049AApr 4, 2000
Antisense modulation of PI3 kinase p110 delta expression
ISIS PHARMACEUTICALS INC88 citations98
US5955589ASep 21, 1999
Gapped 2' modified oligonucleotides
ISIS PHARMACEUTICALS INC127 citations98
US5656612AAug 12, 1997
Antisense oligonucleotide modulation of raf gene expression
ISIS PHARMACEUTICALS INC99 citations98
US7709630B2May 4, 2010
Antisense modulation of connective tissue growth factor expression
ISIS PHARMACEUTICALS INC131 citations97
US6214986B1Apr 10, 2001
Antisense modulation of bcl-x expression
ISIS PHARMACEUTICALS INC86 citations97
US6133246AOct 17, 2000
Antisense oligonucleotide compositions and methods for the modulation of JNK proteins
ISIS PHARMACEUTICALS INC262 citations97
US7148204B2Dec 12, 2006
Antisense modulation of bcl-x expression
ISIS PHARMACEUTICALS INC145 citations96
US6359124B1Mar 19, 2002
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
ISIS PHARMACEUTICALS INC67 citations96
US6258601B1Jul 10, 2001
Antisense modulation of ubiquitin protein ligase expression
ISIS PHARMACEUTICALS INC75 citations96
US6146829ANov 14, 2000
Gapped 2' modified oligonucleotides
ISIS PHARMACEUTICALS INC59 citations96
US6133031AOct 17, 2000
Antisense inhibition of focal adhesion kinase expression
ISIS PHARMACEUTICALS INC54 citations96
US6069008AMay 30, 2000
Antisense modulation of NF-kappa-B p65 subunit expression
ISIS PHARMACEUTICALS INC56 citations96
US6013522AJan 11, 2000
Antisense inhibition of human Smad1 expression
ISIS PHARMACEUTICALS INC86 citations96
US5965722AOct 12, 1999
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
ISIS PHARMACEUTICALS INC53 citations96
US5856455AJan 5, 1999
Gapped 2'-modified oligonucleotides
ISIS PHARMACEUTICALS INC76 citations96
US5837449ANov 17, 1998
Compositions and methods for modulating β-amyloid
ISIS PHARMACEUTICALS INC68 citations96
US5582986ADec 10, 1996
Antisense oligonucleotide inhibition of the ras gene
ISIS PHARMACEUTICALS INC75 citations96
US5563255AOct 8, 1996
Antisense oligonucleotide modulation of raf gene expression
ISIS PHARMACEUTICALS INC77 citations95
US6184212B1Feb 6, 2001
Antisense modulation of human mdm2 expression
ISIS PHARMACEUTICALS INC78 citations94
US7919472B2Apr 5, 2011
Enhanced antisense oligonucleotides
ISIS PHARMACEUTICALS INC37 citations93
US6806258B2Oct 19, 2004
Antisense oligonucleotide modulation of raf gene expression
ISIS PHARMACEUTICALS INC20 citations93
US6784290B1Aug 31, 2004
Antisense oligonucleotide inhibition of ras
ISIS PHARMACEUTICALS INC19 citations93
US6410518B1Jun 25, 2002
Antisense oligonucleotide inhibition of raf gene expression
ISIS PHARMACEUTICALS INC26 citations93
US6395545B1May 28, 2002
Antisense modulation of inhibitor-kappa B kinase-alpha expression
ISIS PHARMACEUTICALS INC16 citations93
US6300132B1Oct 9, 2001
Antisense inhibition of telomeric repeat binding factor 2 expression
ISIS PHARMACEUTICALS INC41 citations93
US6284538B1Sep 4, 2001
Antisense inhibition of PTEN expression
ISIS PHARMACEUTICALS INC38 citations93
US6177246B1Jan 23, 2001
Compositions and methods for modulating β-amyloid
ISIS PHARMACEUTICALS INC43 citations93
US6165789ADec 26, 2000
Antisense modulation of hnRNP A1 expression
ISIS PHARMACEUTICALS INC28 citations93
US6159697ADec 12, 2000
Antisense modulation of Smad7 expression
ISIS PHARMACEUTICALS INC49 citations93
US6043090AMar 28, 2000
Antisense inhibition of human Akt-2 expression
ISIS PHARMACEUTICALS INC20 citations93
BHANOT SANJAY
3 patentsUS9045754B2Jun 2, 2015
Short antisense compounds with gapmer configuration
BHANOT SANJAY56 citations97
US8143230B2Mar 27, 2012
Compounds and methods for modulating expression of PCSK9
BHANOT SANJAY44 citations97
US8188059B2May 29, 2012
Compounds and methods for modulating expression of GCGR
BHANOT SANJAY22 citations96
IONIS PHARMACEUTICALS INC
2 patentsISIS PHARMACETICALS INC
1 patentShowing the top 50 of 141 patents by PatentIndex Score.