Inventor
MCSWIGGEN JAMES
US104 patents
⚠️ This page may combine multiple inventors who share the name “MCSWIGGEN JAMES”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
RIBOZYME PHARM INC
17 patentsUS5972704AOct 26, 1999
HIV nef targeted ribozymes
RIBOZYME PHARM INC221 citations99
US5891684AApr 6, 1999
Base-modified enzymatic nucleic acid
RIBOZYME PHARM INC91 citations99
US5646042AJul 8, 1997
C-myb targeted ribozymes
RIBOZYME PHARM INC123 citations98
US5631359AMay 20, 1997
Hairpin ribozymes
RIBOZYME PHARM INC268 citations98
US6346398B1Feb 12, 2002
Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor
RIBOZYME PHARM INC245 citations97
US6410224B1Jun 25, 2002
Ribozyme treatment of diseases or conditions related to levels of NF-κB
RIBOZYME PHARM INC48 citations96
US6194150B1Feb 27, 2001
Nucleic acid based inhibition of CD40
RIBOZYME PHARM INC45 citations96
US5877021AMar 2, 1999
B7-1 targeted ribozymes
RIBOZYME PHARM INC88 citations96
US5877022AMar 2, 1999
Ribozymes targeted to APO(a) RNA
RIBOZYME PHARM INC167 citations96
US5693535ADec 2, 1997
HIV targeted ribozymes
RIBOZYME PHARM INC84 citations96
US5811300ASep 22, 1998
TNF-α ribozymes
RIBOZYME PHARM INC95 citations95
US5731295AMar 24, 1998
Method of reducing stromelysin RNA via ribozymes
RIBOZYME PHARM INC59 citations94
US5767263AJun 16, 1998
Base-modified enzymatic nucleic acid
RIBOZYME PHARM INC19 citations93
US5616488AApr 1, 1997
IL-5 targeted ribozymes
RIBOZYME PHARM INC23 citations93
US5837542ANov 17, 1998
Intercellular adhesion molecule-1 (ICAM-1) ribozymes
RIBOZYME PHARM INC20 citations92
US5612215AMar 18, 1997
Stromelysin targeted ribozymes
RIBOZYME PHARM INC19 citations91
US5693532ADec 2, 1997
Respiratory syncytial virus ribozymes
RIBOZYME PHARM INC39 citations89
SIRNA THERAPEUTICS INC
14 patentsUS10000754B2Jun 19, 2018
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC35 citations98
US9771588B2Sep 26, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC44 citations98
US9732344B2Aug 15, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC43 citations98
US9657294B2May 23, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC36 citations98
US9181551B2Nov 10, 2015
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC102 citations98
US7923547B2Apr 12, 2011
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC82 citations98
US6673611B2Jan 6, 2004
Nucleic acid molecules with novel chemical compositions capable of modulating gene expression
SIRNA THERAPEUTICS INC218 citations98
US7956176B2Jun 7, 2011
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC42 citations96
US6818447B1Nov 16, 2004
Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor
SIRNA THERAPEUTICS INC49 citations94
US7989612B2Aug 2, 2011
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC36 citations93
US10662428B2May 26, 2020
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC5 citations84
US10351852B2Jul 16, 2019
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC5 citations84
US7897752B2Mar 1, 2011
RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC7 citations84
US7795422B2Sep 14, 2010
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC15 citations84
MCSWIGGEN JAMES
6 patentsUS8202979B2Jun 19, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
MCSWIGGEN JAMES106 citations99
US8846894B2Sep 30, 2014
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
MCSWIGGEN JAMES42 citations98
US8273866B2Sep 25, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
MCSWIGGEN JAMES100 citations98
US7176304B2Feb 13, 2007
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
MCSWIGGEN JAMES187 citations98
US8232383B2Jul 31, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
MCSWIGGEN JAMES27 citations92
US8258288B2Sep 4, 2012
RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA)
MCSWIGGEN JAMES7 citations84
BEIGELMAN LEONID
5 patentsUS8618277B2Dec 31, 2013
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
BEIGELMAN LEONID87 citations98
US8268986B2Sep 18, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
BEIGELMAN LEONID54 citations98
US8242257B2Aug 14, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
BEIGELMAN LEONID29 citations92
US8236944B2Aug 7, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
BEIGELMAN LEONID21 citations92
US7977472B2Jul 12, 2011
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA)
BEIGELMAN LEONID16 citations84
MERCK SHARP & DOHME
3 patentsUS7935812B2May 3, 2011
RNA interference mediated inhibition of hepatitis C virus (HCV) expression using short interfering nucleic acid (siNA)
MERCK SHARP & DOHME28 citations89
US8013143B2Sep 6, 2011
RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA)
MERCK SHARP & DOHME11 citations84
US7915400B2Mar 29, 2011
RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)
MERCK SHARP & DOHME10 citations84
TRANSLATE BIO MA INC
2 patentsRIBOZYME PHARMACEUTICAL INC
1 patentCHIRON CORP
1 patentFEINSTEIN ELENA
1 patentShowing the top 50 of 104 patents by PatentIndex Score.