Inventor
BEIGELMAN LEONID
US222 patents
⚠️ This page may combine multiple inventors who share the name “BEIGELMAN LEONID”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
RIBOZYME PHARM INC
17 patentsUS6362323B1Mar 26, 2002
Non-nucleotide containing nucleic acid
RIBOZYME PHARM INC179 citations99
US6251666B1Jun 26, 2001
Nucleic acid catalysts comprising L-nucleotide analogs
RIBOZYME PHARM INC121 citations99
US6248878B1Jun 19, 2001
Nucleoside analogs
RIBOZYME PHARM INC264 citations99
US6159951ADec 12, 2000
2'-O-amino-containing nucleoside analogs and polynucleotides
RIBOZYME PHARM INC136 citations99
US6117657ASep 12, 2000
Non-nucleotide containing enzymatic nucleic acid
RIBOZYME PHARM INC253 citations99
US5891683AApr 6, 1999
Non-nucleotide containing enzymatic nucleic acid
RIBOZYME PHARM INC104 citations99
US5891684AApr 6, 1999
Base-modified enzymatic nucleic acid
RIBOZYME PHARM INC91 citations99
US5716824AFeb 10, 1998
2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes)
RIBOZYME PHARM INC373 citations99
US5631360AMay 20, 1997
N-phthaloyl-protected 2'-amino-nucleoside phosphoramdites
RIBOZYME PHARM INC157 citations99
US6528640B1Mar 4, 2003
Synthetic ribonucleic acids with RNAse activity
RIBOZYME PHARM INC283 citations98
US6469158B1Oct 22, 2002
Synthesis, deprotection, analysis and purification of RNA and ribozymes
RIBOZYME PHARM INC205 citations98
US6437117B1Aug 20, 2002
Synthesis, deprotection, analysis and purification for RNA and ribozymes
RIBOZYME PHARM INC187 citations98
US6395713B1May 28, 2002
Compositions for the delivery of negatively charged molecules
RIBOZYME PHARM INC367 citations98
US5998203ADec 7, 1999
Enzymatic nucleic acids containing 5'-and/or 3'-cap structures
RIBOZYME PHARM INC784 citations98
US5627053AMay 6, 1997
2'deoxy-2'-alkylnucleotide containing nucleic acid
RIBOZYME PHARM INC1,461 citations98
US6602858B2Aug 5, 2003
Nucleic acid catalysts comprising L-nucleotide analogs
RIBOZYME PHARM INC68 citations96
US5985621ANov 16, 1999
2'-deoxy-2'-alkylnucleotide containing nucleic acid
RIBOZYME PHARM INC63 citations95
SIRNA THERAPEUTICS INC
13 patentsUS7109165B2Sep 19, 2006
Conjugates and compositions for cellular delivery
SIRNA THERAPEUTICS INC90 citations99
US6849726B2Feb 1, 2005
Non-nucleotide containing RNA
SIRNA THERAPEUTICS INC129 citations99
US10000754B2Jun 19, 2018
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC35 citations98
US9771588B2Sep 26, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC44 citations98
US9732344B2Aug 15, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC43 citations98
US9657294B2May 23, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC36 citations98
US9181551B2Nov 10, 2015
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC102 citations98
US7923547B2Apr 12, 2011
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC82 citations98
US6673611B2Jan 6, 2004
Nucleic acid molecules with novel chemical compositions capable of modulating gene expression
SIRNA THERAPEUTICS INC218 citations98
US6617438B1Sep 9, 2003
Oligoribonucleotides with enzymatic activity
SIRNA THERAPEUTICS INC312 citations97
US7956176B2Jun 7, 2011
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC42 citations96
US6818759B2Nov 16, 2004
2′-O-alkylthioalkyl and 2′-C-alkylthioalkyl-containing nucleic acids
SIRNA THERAPEUTICS INC31 citations96
US6649751B2Nov 18, 2003
Synthesis, deprotection, analysis and purification of RNA and ribozymes
SIRNA THERAPEUTICS INC68 citations95
ALIOS BIOPHARMA INC
9 patentsUS9249174B2Feb 2, 2016
Substituted nucleosides, nucleotides and analogs thereof
ALIOS BIOPHARMA INC79 citations99
US9243022B2Jan 26, 2016
Substituted nucleosides, nucleotides and analogs thereof
ALIOS BIOPHARMA INC72 citations99
US9605018B2Mar 28, 2017
Substituted nucleotide analogs
ALIOS BIOPHARMA INC47 citations98
US9278990B2Mar 8, 2016
Substituted nucleotide analogs
ALIOS BIOPHARMA INC60 citations98
US8980865B2Mar 17, 2015
Substituted nucleotide analogs
ALIOS BIOPHARMA INC95 citations98
US9603864B2Mar 28, 2017
Substituted nucleosides, nucleotides and analogs thereof
ALIOS BIOPHARMA INC56 citations97
US9603863B2Mar 28, 2017
Substituted nucleosides, nucleotides and analogs thereof
ALIOS BIOPHARMA INC42 citations97
US8895723B2Nov 25, 2014
Methods of preparing substituted nucleotide analogs
ALIOS BIOPHARMA INC44 citations96
US8846896B2Sep 30, 2014
Methods of preparing substituted nucleotide analogs
ALIOS BIOPHARMA INC45 citations96
BEIGELMAN LEONID
5 patentsUS8618277B2Dec 31, 2013
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
BEIGELMAN LEONID87 citations98
US8268986B2Sep 18, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
BEIGELMAN LEONID54 citations98
US8877731B2Nov 4, 2014
Azido nucleosides and nucleotide analogs
BEIGELMAN LEONID70 citations97
US8772474B2Jul 8, 2014
Cyclic nucleotide analogs
BEIGELMAN LEONID76 citations97
US8188247B2May 29, 2012
Conjugates and compositions for cellular delivery
BEIGELMAN LEONID36 citations96
MCSWIGGEN JAMES
4 patentsUS8202979B2Jun 19, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
MCSWIGGEN JAMES106 citations99
US8846894B2Sep 30, 2014
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
MCSWIGGEN JAMES42 citations98
US8273866B2Sep 25, 2012
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA)
MCSWIGGEN JAMES100 citations98
US7176304B2Feb 13, 2007
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
MCSWIGGEN JAMES187 citations98
SMITH DAVID BERNARD
1 patentINTERMUNE INC
1 patentShowing the top 50 of 222 patents by PatentIndex Score.