Inventor

ARISON BYRON H

US45 patents

Patents

45 patents

US5952347ASep 14, 1999

Biological process for producing 17β-N-monosubstituted carbamoyl-11-oxo-4-aza-5-α-androst-3-one testosterone-5-α reductase inhibitors

MERCK & CO INC38 citations90

US5187074AFeb 16, 1993

Method of hydroxylation with ATCC 55086

MERCK & CO INC40 citations90

US5087702AFeb 11, 1992

Microbial transformation process for producing an antihypertensive product

MERCK & CO INC21 citations82

US5149701ASep 22, 1992

C-31 methylated FR-900520 cyclic hemiketal immunosuppressant agents

MERCK & CO INC20 citations81

US4987139AJan 22, 1991

FK-520 microbial transformation product

MERCK & CO INC19 citations81

US5290772AMar 1, 1994

Immunosuppressant agent

MERCK & CO INC7 citations73

US5210030AMay 11, 1993

Process for selectively acylating immunomycin

MERCK & CO INC16 citations73

US5068323ANov 26, 1991

Thermally re-arranged FK-506 derivatives having immunosuppressant activity

MERCK & CO INC14 citations73

US4997849AMar 5, 1991

Microbial transformation of simvastatin

MERCK & CO INC16 citations73

US4975372ADec 4, 1990

Microbial transformation product of L-683,590

MERCK & CO INC8 citations73

US5352783AOct 4, 1994

Microbial transformation product having immunosuppressive activity

MERCK & CO INC14 citations72

US5273979ADec 28, 1993

C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent

MERCK & CO INC8 citations71

US5221625AJun 22, 1993

Cyclcic FR-900520 microbial biotransformation agent

MERCK & CO INC14 citations71

US5192671AMar 9, 1993

Process for the glycosylation of avermectin compounds

MERCK & CO INC8 citations71

US5324644AJun 28, 1994

Process for producing immunosuppressant agent

MERCK & CO INC13 citations67

US4965200AOct 23, 1990

Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs

MERCK & CO INC16 citations67

US5270187ADec 14, 1993

Microbial transformation product

MERCK & CO INC2 citations62

US5268370ADec 7, 1993

Microbial transformation product of L-679,934

MERCK & CO INC2 citations62

US5252612AOct 12, 1993

Microbial immunosoppressant agent

MERCK & CO INC3 citations62

US5250422AOct 5, 1993

Biotransformation process for the production of invermectin derivatives

MERCK & CO INC2 citations62

US5138052AAug 11, 1992

L-683,590 microbial transformation product

MERCK & CO INC4 citations62

US5057608AOct 15, 1991

Immunoregulants, immunosuppressants, process to make ring expanded macrolide related to FK-506/FK-520

MERCK & CO INC3 citations62

US5612217AMar 18, 1997

Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthesis of HIV protease inhibitors

MERCK & CO INC4 citations61

US5468771ANov 21, 1995

Cholesterol lowering compound

MERCK & CO INC2 citations61

US5202258AApr 13, 1993

Immunosuppressant-producing culture

MERCK & CO INC2 citations61

US5140042AAug 18, 1992

28-hydroxy ivermectin aglycone

MERCK & CO INC4 citations60

US5124258AJun 23, 1992

Fermentation process for the preparation of ivermectin aglycone

MERCK & CO INC5 citations60

US5272068ADec 21, 1993

Process for producing immunosuppressant agent L-683942 by fermentation

MERCK & CO INC4 citations55

US4738982AApr 19, 1988

HMG-CoA reductase inhibitors

MERCK & CO INC3 citations55

US5362752ANov 8, 1994

Chemical compounds

MERCK & CO INC0 citations51

US5359096AOct 25, 1994

Cholesterol lowering compounds

MERCK & CO INC0 citations51

US5322855AJun 21, 1994

Cholesterol lowering compounds

MERCK & CO INC1 citations51

US5219985AJun 15, 1993

Antifungal agent

MERCK & CO INC1 citations51

US5478929ADec 26, 1995

Bioconversion products of 27-hydroxy avermectin

MERCK & CO INC0 citations49

US5169769ADec 8, 1992

Method of hydroxylating substituted 3-aminopyridinones using mammalian tissue

MERCK & CO INC0 citations48

ARISON BYRON H

Patents

Quinoline leukotriene antagonists

Process for preparation of novel angiotensin II antagonists

Microbial transformation process for preparing anti-hypertensive products

Immunosuppressant compound

Novel derivatives of C-076 compounds

Cholesterol lowering compounds

Cholesterol lowering compounds produced by directed biosynthesis

C-21 hydroxylated FK-506 antagonist

Synthesis of protease inhibitor

α v integrin receptor antagonists

Biological process for producing 17β-N-monosubstituted carbamoyl-11-oxo-4-aza-5-α-androst-3-one testosterone-5-α reductase inhibitors

Method of hydroxylation with ATCC 55086

Microbial transformation process for producing an antihypertensive product

C-31 methylated FR-900520 cyclic hemiketal immunosuppressant agents

FK-520 microbial transformation product

Immunosuppressant agent

Process for selectively acylating immunomycin

Thermally re-arranged FK-506 derivatives having immunosuppressant activity

Microbial transformation of simvastatin

Microbial transformation product of L-683,590

Microbial transformation product having immunosuppressive activity

C-31 desmethyl FR-900520 cyclic hemiketal immunosuppressant agent

Cyclcic FR-900520 microbial biotransformation agent

Process for the glycosylation of avermectin compounds

Process for producing immunosuppressant agent

Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs

Microbial transformation product

Microbial transformation product of L-679,934

Microbial immunosoppressant agent

Biotransformation process for the production of invermectin derivatives

L-683,590 microbial transformation product

Immunoregulants, immunosuppressants, process to make ring expanded macrolide related to FK-506/FK-520

Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthesis of HIV protease inhibitors

Cholesterol lowering compound

Immunosuppressant-producing culture

28-hydroxy ivermectin aglycone

Fermentation process for the preparation of ivermectin aglycone

Process for producing immunosuppressant agent L-683942 by fermentation

HMG-CoA reductase inhibitors

Chemical compounds

Cholesterol lowering compounds

Cholesterol lowering compounds

Antifungal agent

Bioconversion products of 27-hydroxy avermectin

Method of hydroxylating substituted 3-aminopyridinones using mammalian tissue