Inventor

VALENZUELA DAVID M

US87 patents

⚠️ This page may combine multiple inventors who share the name “VALENZUELA DAVID M”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

VALENZUELA DAVID M

REGENERON PHARMA

Methods of modifying eukaryotic cells

Methods and compositions for the targeted modification of a genome

MiRNA-regulated differentiation-dependent self-deleting cassette

Method for making homozygous genetic modifications

Method for making genetic modifications

Method for generating an animal homozygous for a genetic modification

Genome mutation by intron insertion into an embryonic stem cell genome

miRNA-regulated differentiation-dependent self-deleting cassette

Targeted modification of rat genome

Methods and compositions for the targeted modification of a mouse embryonic stem cell genome

Methods and compositions for the targeted modification of a mouse genome

Genetic modification of rats

Methods of making a nucleic acid encoding a human variable region

Methods of producing hybrid antibodies

Genetically modified mice that produce hybrid antibodies

Methods of producing hybrid antibodies

Method for genetically modifying isolated non-human mammalian cell by homologous recombination

Methods and compositions for generating a mouse

Methods and compositions for generating a mouse

Methods and compositions for generating a mouse

Promoter-regulated differentiation-dependent self-deleting cassette

Promoter-regulated differentiation-dependent self-deleting cassette

Tyrosine kinase receptors and ligands

Tie ligand-3, methods of making and uses thereof

Tyrosine kinase receptors and ligands

Nuclease-mediated DNA assembly

Morphogenic proteins

Methods and compositions for the targeted modification of a mouse ES cell genome

Mice that produce hybrid antibodies

Genetically modified mice that produce hybrid antibodies

Mice that produce hybrid antibodies

Mouse embryonic stem cells comprising a hybrid heavy chain immunoglobulin locus

Mice that produce hybrid antibodies

Methods of making a nucleic acid encoding a human variable region

Nuclease-mediated targeting with large targeting vectors

Methods of modifying eukaryotic cells

Nuclease-mediated targeting with large targeting vectors

Methods of modifying eukaryotic cells

Promoter-regulated differentiation-dependent self-deleting cassette

Methods of producing hybrid antibodies

Methods and compositions for modifying a targeted locus

Methods for producing a mouse XY embryonic (ES) cell line capable of producing a fertile XY female mouse in an F0 generation

MiRNA-regulated differentiation-dependent self-deleting cassette

miRNA-regulated differentiation-dependent self-deleting cassette

MURPHY ANDREW J

Hybrid antibodies comprising human variable regions and mouse constant regions produced in a genetically modified mouse

Methods of producing hybrid antibodies

ECONOMIDES ARIS N

Method for genetically modifying mouse embryonic stem cell by homologous recombination

FRENDEWEY DAVID

Promoter-regulated differentiation-dependent self-deleting cassette

POUEYMIROU WILLIAM

Conditioned culture media

ONCOGENE SCIENCE INC

Monoclonal antibodies recognizing parathyroid hormone-like protein