Inventor
TSAI SHENGDAR
US18 patents
Patents
18 patentsUS9567603B2Feb 14, 2017
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL86 citations99
US10544433B2Jan 28, 2020
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL34 citations98
US10138476B2Nov 27, 2018
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL35 citations98
US9885033B2Feb 6, 2018
Increasing specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL95 citations98
US10844403B2Nov 24, 2020
Increasing specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL31 citations97
US11098326B2Aug 24, 2021
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL16 citations94
US9822407B2Nov 21, 2017
Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)
MASSACHUSETTS GEN HOSPITAL23 citations94
US9850484B2Dec 26, 2017
Comprehensive in vitro reporting of cleavage events by sequencing (Circle-seq)
MASSACHUSETTS GEN HOSPITAL19 citations92
US11920152B2Mar 5, 2024
Increasing specificity for RNA-guided genome editing
MASSACHUSETTS GEN HOSPITAL4 citations85
US10526589B2Jan 7, 2020
Multiplex guide RNAs
MASSACHUSETTS GEN HOSPITAL8 citations84
US10501794B2Dec 10, 2019
Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq)
MASSACHUSETTS GEN HOSPITAL11 citations84
US10011850B2Jul 3, 2018
Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing
MASSACHUSETTS GEN HOSPITAL15 citations84
US9988674B2Jun 5, 2018
Full interrogation of nuclease DSBs and sequencing (find-seq)
MASSACHUSETTS GEN HOSPITAL12 citations84
US12104207B2Oct 1, 2024
Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq)
MASSACHUSETTS GEN HOSPITAL0 citations62
US11028429B2Jun 8, 2021
Full interrogation of nuclease DSBs and sequencing (FIND-seq)
MASSACHUSETTS GEN HOSPITAL1 citations62
US10738303B2Aug 11, 2020
Comprehensive in vitro reporting of cleavage events by sequencing (CIRCLE-seq)
MASSACHUSETTS GEN HOSPITAL1 citations62
US12286641B2Apr 29, 2025
Methods for increasing efficiency of nuclease-induced homology-directed repair
MASSACHUSETTS GEN HOSPITAL0 citations59
US11021718B2Jun 1, 2021
Methods for increasing efficiency of nuclease-induced homology-directed repair
MASSACHUSETTS GEN HOSPITAL0 citations59