Inventor
GRABOWSKI EDWARD J J
US34 patents
⚠️ This page may combine multiple inventors who share the name “GRABOWSKI EDWARD J J”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
MERCK & CO INC
33 patentsUS6569461B1May 27, 2003
Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
MERCK & CO INC53 citations93
US5922864AJul 13, 1999
Efficient synthesis of a 1,4-dihydro2H-3,1-benzoxazin-2-one
MERCK & CO INC17 citations92
US5633405AMay 27, 1997
Asymmetric synthesis of (-)-6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxanzin-2-one
MERCK & CO INC21 citations92
US5157129AOct 20, 1992
Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide
MERCK & CO INC23 citations90
US4914222AApr 3, 1990
Crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters and process
MERCK & CO INC28 citations86
US4894450AJan 16, 1990
Process for 2-(aminoalkylthio) carbapenems
MERCK & CO INC20 citations81
US5698741ADec 16, 1997
Asymmetric synthesis of (-)6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one
MERCK & CO INC5 citations74
US5391772AFeb 21, 1995
Converting an alcohol to an azide with SN 2 inversion using a phosphoryl azide
MERCK & CO INC9 citations74
US5434152AJul 18, 1995
Asymmetric synthesis of (S)-(-)-6-chloro-4- cyclopropyl-3,4-dihydro-4-[(2-pyridyl)ethynyl]-2(1H)-quinazolinone
MERCK & CO INC13 citations73
US4968814ANov 6, 1990
(S)-Alkyl 3-(thien-2-ylthio)butyrate and analogs and synthesis thereof
MERCK & CO INC15 citations73
US4940813AJul 10, 1990
Resolution of a carboxylic acid
MERCK & CO INC9 citations73
US4859771AAug 22, 1989
Process for resolution and racemization of amines with acidic α-hydrogens
MERCK & CO INC7 citations73
US4582931AApr 15, 1986
Preparation of 2-Deutero-D-serine
MERCK & CO INC16 citations73
US4233457ANov 11, 1980
Process for preparing indenyl acetic acids
MERCK & CO INC9 citations72
US4670578AJun 2, 1987
Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
MERCK & CO INC7 citations70
US6114569ASep 5, 2000
Efficient synthesis of A 1,4-dihydro-2H-3,1-benzoxazin-2-one
MERCK & CO INC4 citations62
US5952528ASep 14, 1999
Process for enhancing the optical purity
MERCK & CO INC2 citations62
US5457201AOct 10, 1995
Chiral resolution process
MERCK & CO INC4 citations62
US5093498AMar 3, 1992
Trifluoromethylbenzyl containing quaternary salts
MERCK & CO INC4 citations62
US5011942AApr 30, 1991
Process for racemizing an enantiomer of 5,6-dihydro-4-alkylamino-4H-thieno(or furo) [2,3-B]-thiopyran-2-sulfonamide-7,7-dioxide
MERCK & CO INC4 citations62
US4578509AMar 25, 1986
Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis
MERCK & CO INC4 citations62
US4149012AApr 10, 1979
Synthesis of racemic 3-fluoro-alanine and its salts
MERCK & CO INC2 citations61
US3972921AAug 3, 1976
Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts
MERCK & CO INC5 citations61
US4070360AJan 24, 1978
4,9-Diazatricyclo[6.2.2.02,7 ]dodec-11-enes
MERCK & CO INC1 citations60
US4033968AJul 5, 1977
Diazatetracyclododecanes
MERCK & CO INC1 citations60
US5618934AApr 8, 1997
Boronic acid compound
MERCK & CO INC0 citations51
US5442056AAug 15, 1995
Preparation of 2-aryl carbapenems
MERCK & CO INC1 citations51
US6281391B1Aug 28, 2001
Synthesis of methylthiophenyl hydroxyketones
MERCK & CO INC0 citations50
US4121041AOct 17, 1978
7-(Amidinothio)acetamido-7-methoxy cephalosporins
MERCK & CO INC0 citations50
US4070359AJan 24, 1978
Process for preparing 5,11-diazatetracyclododecanes
MERCK & CO INC0 citations49
US5070022ADec 3, 1991
Enzymic process for preparing leukotriene antagonists
MERCK & CO INC0 citations48
US6268510B1Jul 31, 2001
Rearrangement process and tricyclic and tetracyclic compounds
MERCK & CO INC1 citations47
US5693805ADec 2, 1997
Process to derivatives of piperizinylcamphorsulfonyl oxytocin antagonists
MERCK & CO INC1 citations46