Inventor
SCHIENE KLAUS
DE56 patents
⚠️ This page may combine multiple inventors who share the name “SCHIENE KLAUS”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
GRUENENTHAL GMBH
29 patentsUS8017772B2Sep 13, 2011
Substituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain
GRUENENTHAL GMBH9 citations84
US7879858B2Feb 1, 2011
Substituted tetrahydropyrrolopyrazine compounds and the use thereof in pharmaceutical compositions
GRUENENTHAL GMBH9 citations84
US7625900B2Dec 1, 2009
Sutstituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain
GRUENENTHAL GMBH12 citations84
US9320729B2Apr 26, 2016
Pharmaceutical composition comprising (1r,4r)-6′-flouro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
GRUENENTHAL GMBH5 citations83
US7300939B2Nov 27, 2007
Substituted 1-propiolylpiperazine compounds, their preparation and use
GRUENENTHAL GMBH9 citations73
US7786160B2Aug 31, 2010
Combination of selected analgesics and COX-II inhibitors
GRUENENTHAL GMBH6 citations72
US11311504B2Apr 26, 2022
Pharmaceutical composition comprising (1R,4R)-6′- fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro [cyclohexane-1,1′-pyrano- [3,4,b ]indol] -4-amine and paracetamol or propacetamol
GRUENENTHAL GMBH1 citations62
US8912226B2Dec 16, 2014
Pharmaceutical composition comprising (1r,4r) -6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a NSAR
GRUENENTHAL GMBH2 citations62
US7893069B2Feb 22, 2011
Substituted imidazo[2,1-b]thiazole compounds and uses thereof
GRUENENTHAL GMBH4 citations62
US10829480B2Nov 10, 2020
3-((hetero-)aryl)-alkyl-8-amino-2-oxo-l,3-diaza-spiro-[4.5]-decane derivatives
GRUENENTHAL GMBH1 citations61
US7420056B2Sep 2, 2008
Substituted bicyclic imidazo-3-ylamine compounds
GRUENENTHAL GMBH7 citations61
US10398657B2Sep 3, 2019
Method of inhibiting chronification of pain
GRUENENTHAL GMBH1 citations56
US8367700B2Feb 5, 2013
Substituted 4-(1.2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulators
GRUENENTHAL GMBH1 citations52
US7871999B2Jan 18, 2011
Substituted thiazoles and their use for producing drugs
GRUENENTHAL GMBH2 citations52
US10813890B2Oct 27, 2020
Pharmaceutical combination
GRUENENTHAL GMBH0 citations51
US10471079B2Nov 12, 2019
Combination of selected analgesics and COX-II inhibitors
GRUENENTHAL GMBH0 citations51
US10206890B2Feb 19, 2019
Pharmaceutical combination
GRUENENTHAL GMBH0 citations51
US10076510B2Sep 18, 2018
Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a propionic acid derivative
GRUENENTHAL GMBH1 citations51
US9308196B2Apr 12, 2016
Pharmaceutical composition comprising (1 r,4r) -6'-fluoro-N ,N-dimethyl-4-phenyl-4',9'-d ihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4,b]indol]-4-amine and an oxicam
GRUENENTHAL GMBH1 citations51
US7342133B2Mar 11, 2008
Substituted amino compounds as 5-HT/NA uptake inhibitors
GRUENENTHAL GMBH0 citations51
US9120756B2Sep 1, 2015
Substituted phenylureas and phenylamides as vanilloid receptor ligands
GRUENENTHAL GMBH1 citations50
US9624209B2Apr 18, 2017
Substituted phenylureas and phenylamides as vanilloid receptor ligands
GRUENENTHAL GMBH0 citations49
US8003701B2Aug 23, 2011
Method of inhibiting inflammatory pain
GRUENENTHAL GMBH0 citations48
US10813891B2Oct 27, 2020
Method of inhibiting chronification of pain
GRUENENTHAL GMBH0 citations46
US7754754B2Jul 13, 2010
Pharmaceutical formulations containing substituted 2 heteroarylaminoacetic acid compounds
GRUENENTHAL GMBH0 citations42
US7432296B2Oct 7, 2008
Pharmaceutical formulations containing substituted 2-aryl-aminoacetic acid compounds and/or substituted 2-heteroaryl-aminoacetic acid compounds
GRUENENTHAL GMBH0 citations42
US9855286B2Jan 2, 2018
Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-di methyl-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano-[3,4,b]indol]-4-amine and a salicylic acid component
GRUENENTHAL GMBH0 citations41
US7858613B2Dec 28, 2010
Substituted benzo-condensed cycloheptanone derivatives and their use for producing drugs
GRUENENTHAL GMBH0 citations41
US10807989B2Oct 20, 2020
3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
GRUENENTHAL GMBH0 citations40
FRANK ROBERT
10 patentsUS8642623B2Feb 4, 2014
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions
FRANK ROBERT14 citations83
US8252816B2Aug 28, 2012
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions
FRANK ROBERT10 citations83
US8084484B2Dec 27, 2011
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
FRANK ROBERT10 citations83
US8334315B2Dec 18, 2012
Substituted aromatic carboxamide and urea derivatives as vanilloid receptor ligands
FRANK ROBERT6 citations71
US8592471B2Nov 26, 2013
Substituted phenylureas and phenylamides as vanilloid receptor ligands
FRANK ROBERT3 citations61
US8642775B2Feb 4, 2014
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
FRANK ROBERT3 citations60
US8791268B2Jul 29, 2014
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions
FRANK ROBERT0 citations51
US8785474B2Jul 22, 2014
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions
FRANK ROBERT0 citations51
US8946204B2Feb 3, 2015
Substituted phenylureas and phenylamides as vanilloid receptor ligands
FRANK ROBERT0 citations50
US8735426B2May 27, 2014
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions
FRANK ROBERT0 citations41
SCHIENE KLAUS
4 patentsUS8618177B2Dec 31, 2013
Method of treating pain caused by inflammation
SCHIENE KLAUS1 citations60
US8420691B2Apr 16, 2013
Combination of selected analgesics and COX-II inhibitors
SCHIENE KLAUS2 citations60
US8846765B2Sep 30, 2014
Pharmaceutical combination
SCHIENE KLAUS1 citations49
US8404749B2Mar 26, 2013
Method of inhibiting inflammatory pain
SCHIENE KLAUS0 citations49
OBERBOERSCH STEFAN
3 patentsNOXXON PHARMA AG
1 patentGRUENENTHAL CHEMIE
1 patentLEE JEEWOO
1 patentMERLA BEATRIX
1 patentShowing the top 50 of 56 patents by PatentIndex Score.