Inventor
KRUSE LAWRENCE I
US47 patents
⚠️ This page may combine multiple inventors who share the name “KRUSE LAWRENCE I”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SMITHKLINE BECKMAN CORP
28 patentsUS4798843AJan 17, 1989
2-mercaproimidazole dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP32 citations92
US4760089AJul 26, 1988
Irreversible dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP27 citations91
US4532331AJul 30, 1985
1-Benzyl-2-aminomethyl imidazole derivatives
SMITHKLINE BECKMAN CORP23 citations82
US4749717AJun 7, 1988
Dopamine-beta-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP7 citations74
US4719223AJan 12, 1988
Imidazolethiol dopamine-beta-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP6 citations74
US4707485ANov 17, 1987
Substituted te[1]trahydroisoquinoline derivatives having β-adrenergic receptor activity
SMITHKLINE BECKMAN CORP11 citations74
US4634711AJan 6, 1987
Pyridylalkyl imidazole-2-thiols
SMITHKLINE BECKMAN CORP10 citations74
US4454337AJun 12, 1984
Semicarbazide intermediates for preparing 4-substituted indoles
SMITHKLINE BECKMAN CORP8 citations74
US4394514AJul 19, 1983
Processes for preparing 4-substituted indoles
SMITHKLINE BECKMAN CORP9 citations74
US4835154AMay 30, 1989
1-aralykyl-5-piperazinylmethyl-2-mercaptoimidazoles and 2-alkylthioimidazoles and their use as dopamine-βhydroxylase inhibitors
SMITHKLINE BECKMAN CORP10 citations73
US4728741AMar 1, 1988
1-substituted-2-mercapto benzimidazole compounds and intermediates
SMITHKLINE BECKMAN CORP4 citations63
US4707488ANov 17, 1987
Dopamine-β-hydroxylase inhibitors and use thereof
SMITHKLINE BECKMAN CORP2 citations63
US4935438AJun 19, 1990
Dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP4 citations62
US4882348ANov 21, 1989
2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP4 citations62
US4839371AJun 13, 1989
3-aralkyl-2-mercaptoyridines as dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP5 citations62
US4772723ASep 20, 1988
Dopamine β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP3 citations62
US4743613AMay 10, 1988
Ester prodrugs of dopamine-β-hydroxylase, inhibitors, composition containing them, and method of using them to inhibit dopamine-β-hydroxylase activity
SMITHKLINE BECKMAN CORP3 citations62
US4876266AOct 24, 1989
1-aralkyl-2-mercaptoimidazolines as DBH inhibitors
SMITHKLINE BECKMAN CORP5 citations61
US4859779AAug 22, 1989
Dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP3 citations61
US4762850AAug 9, 1988
Dopamine-beta-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP2 citations61
US4761415AAug 2, 1988
Dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP3 citations61
US4873357AOct 10, 1989
Trifluoro acetyl-cyano-aniline intermediates for dopamine-βhydroxylase inhibitors
SMITHKLINE BECKMAN CORP0 citations52
US4857540AAug 15, 1989
Dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP0 citations52
US4810811AMar 7, 1989
Dopamine-beta-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP0 citations52
US4767862AAug 30, 1988
Substituted tetrahydro isoquinoline intermediates
SMITHKLINE BECKMAN CORP0 citations52
US4761480AAug 2, 1988
P-toluene-sulfonyl-oxy substituted pyridines
SMITHKLINE BECKMAN CORP0 citations52
US4912226AMar 27, 1990
Intermediate to dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP0 citations51
US4837353AJun 6, 1989
Dopamine-β-hydroxylase inhibitors
SMITHKLINE BECKMAN CORP1 citations50
ADOLOR CORP
11 patentsUS5646151AJul 8, 1997
Kappa agonist compounds and pharmaceutical formulations thereof
ADOLOR CORP99 citations98
US5981513ANov 9, 1999
Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
ADOLOR CORP30 citations96
US5763445AJun 9, 1998
Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith
ADOLOR CORP49 citations96
US5688955ANov 18, 1997
Kappa agonist compounds and pharmaceutical formulations thereof
ADOLOR CORP66 citations96
US5744458AApr 28, 1998
Kappa agonist compounds and pharmaceutical formulations thereof
ADOLOR CORP36 citations92
US6180623B1Jan 30, 2001
Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
ADOLOR CORP14 citations82
US6028063AFeb 22, 2000
Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
ADOLOR CORP15 citations82
US5945443AAug 31, 1999
Kappa agonist compounds and pharmaceutical formulations thereof
ADOLOR CORP14 citations82
US7294647B2Nov 13, 2007
Kappa agonist compounds and pharmaceutical formulations thereof
ADOLOR CORP1 citations63
US6960612B2Nov 1, 2005
Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
ADOLOR CORP0 citations52
USRE38133EJun 3, 2003
Kappa agonist compounds and pharmaceutical formulations thereof
ADOLOR CORP1 citations52