Inventor
SHEPARD H MICHAEL
US59 patents
⚠️ This page may combine multiple inventors who share the name “SHEPARD H MICHAEL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
HALOZYME INC
21 patentsUS11066656B2Jul 20, 2021
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC30 citations98
US11041149B2Jun 22, 2021
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC32 citations98
US10865400B2Dec 15, 2020
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC25 citations98
US12091692B2Sep 17, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC3 citations86
US12104185B2Oct 1, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC2 citations84
US11952600B2Apr 9, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC2 citations84
US10137104B2Nov 27, 2018
Combination therapy with an anti-hyaluronan agent and therapeutic agent
HALOZYME INC9 citations82
US12371685B2Jul 29, 2025
PH20 polypeptide variants with a modification at position 324 of the PH20 polypeptide and a method of making thereof
HALOZYME INC0 citations73
US12264345B1Apr 1, 2025
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12195773B2Jan 14, 2025
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12152262B2Nov 26, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12123035B2Oct 22, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12110520B2Oct 8, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12104184B2Oct 1, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12077791B2Sep 3, 2024
PH20 polypeptide variants with a modification at position 309 of the PH20 polypeptide and a method of making thereof
HALOZYME INC1 citations73
US12060590B2Aug 13, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12054758B2Aug 6, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12049652B2Jul 30, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC0 citations73
US12037618B2Jul 16, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC1 citations73
US12018298B2Jun 25, 2024
PH20 polypeptide variants, formulations and uses thereof
HALOZYME INC1 citations73
US11584923B2Feb 21, 2023
Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same
HALOZYME INC0 citations62
GENENTECH INC
10 patentsUS6399063B1Jun 4, 2002
Monoclonal antibodies directed to the HER2 receptor
GENENTECH INC282 citations99
US6387371B1May 14, 2002
Monoclonal antibodies directed to the HER2 receptor
GENENTECH INC272 citations99
US6165464ADec 26, 2000
Monoclonal antibodies directed to the HER2 receptor
GENENTECH INC363 citations99
US5772997AJun 30, 1998
Monoclonal antibodies directed to the HER2 receptor
GENENTECH INC437 citations99
US5770195AJun 23, 1998
Monoclonal antibodies directed to the her2 receptor
GENENTECH INC492 citations99
US5720954AFeb 24, 1998
Monoclonal antibodies directed to the HER2 receptor
GENENTECH INC328 citations99
US5677171AOct 14, 1997
Monoclonal antibodies directed to the HER2 receptor
GENENTECH INC924 citations99
US6333169B1Dec 25, 2001
HER2 extracellular domain
GENENTECH INC151 citations97
US6015567AJan 18, 2000
HER2 extracellular domain
GENENTECH INC283 citations97
US4963354AOct 16, 1990
Use of tumor necrosis factor (TNF) as an adjuvant
GENENTECH INC97 citations95
NEWBIOTICS INC
5 patentsUS6245750B1Jun 12, 2001
Enzyme catalyzed therapeutic agents
NEWBIOTICS INC60 citations96
US6339151B1Jan 15, 2002
Enzyme catalyzed therapeutic agents
NEWBIOTICS INC43 citations94
US6495553B1Dec 17, 2002
Methods and compositions for overcoming resistance to biologic and chemotherapy
NEWBIOTICS INC21 citations92
US6683061B1Jan 27, 2004
Enzyme catalyzed therapeutic activation
NEWBIOTICS INC16 citations91
US6159706ADec 12, 2000
Application of enzyme prodrugs as anti-infective agents
NEWBIOTICS INC12 citations74
CELMED ONCOLOGY USA INC
5 patentsUS7419968B1Sep 2, 2008
Methods for treating therapy-resistant tumors
CELMED ONCOLOGY USA INC9 citations84
US7462605B2Dec 9, 2008
Phosphoramidate compounds and methods of use
CELMED ONCOLOGY USA INC7 citations63
US7465734B2Dec 16, 2008
Methods and compositions for overcoming resistance to biologic and chemotherapy
CELMED ONCOLOGY USA INC2 citations62
US7138388B2Nov 21, 2006
Methods to treat autoimmune and inflammatory conditions
CELMED ONCOLOGY USA INC5 citations62
US7601703B2Oct 13, 2009
Enzyme catalyzed therapeutic agents
CELMED ONCOLOGY USA INC3 citations61
CANJI INC
2 patentsWEI GE
1 patentUNIV NORTHWESTERN
1 patentJIANG PING
1 patentMANEVAL DANIEL C
1 patentGENZYME CORP
1 patentUNIV CALIFORNIA
1 patentSHEPARD H MICHAEL
1 patentShowing the top 50 of 59 patents by PatentIndex Score.