Inventor
SANGHVI YOGESH S
US34 patents
⚠️ This page may combine multiple inventors who share the name “SANGHVI YOGESH S”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
ISIS PHARMACEUTICALS INC
32 patentsUS6867294B1Mar 15, 2005
Gapped oligomers having site specific chiral phosphorothioate internucleoside linkages
ISIS PHARMACEUTICALS INC380 citations99
US5777092AJul 7, 1998
Heteroatomic oligonucleoside linkages
ISIS PHARMACEUTICALS INC128 citations99
US5677437AOct 14, 1997
Heteroatomic oligonucleoside linkages
ISIS PHARMACEUTICALS INC1,250 citations99
US5623070AApr 22, 1997
Heteroatomic oligonucleoside linkages
ISIS PHARMACEUTICALS INC1,420 citations99
US5489677AFeb 6, 1996
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
ISIS PHARMACEUTICALS INC1,836 citations99
US5386023AJan 31, 1995
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
ISIS PHARMACEUTICALS INC1,009 citations99
US5378825AJan 3, 1995
Backbone modified oligonucleotide analogs
ISIS PHARMACEUTICALS INC1,016 citations99
US5223618AJun 29, 1993
4'-desmethyl nucleoside analog compounds
ISIS PHARMACEUTICALS INC578 citations99
US6222025B1Apr 24, 2001
Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefrom
ISIS PHARMACEUTICALS INC342 citations98
US6166197ADec 26, 2000
Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions
ISIS PHARMACEUTICALS INC417 citations98
US5965721AOct 12, 1999
Backbone modified oligonucleotide analogues
ISIS PHARMACEUTICALS INC140 citations98
US5610289AMar 11, 1997
Backbone modified oligonucleotide analogues
ISIS PHARMACEUTICALS INC1,639 citations98
US5541307AJul 30, 1996
Backbone modified oligonucleotide analogs and solid phase synthesis thereof
ISIS PHARMACEUTICALS INC1,382 citations98
US6359124B1Mar 19, 2002
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
ISIS PHARMACEUTICALS INC67 citations96
US5965722AOct 12, 1999
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
ISIS PHARMACEUTICALS INC53 citations96
US5808023ASep 15, 1998
Modified oligonucleotides
ISIS PHARMACEUTICALS INC87 citations96
US5792844AAug 11, 1998
Oligonucleoside linkages containing adjacent nitrogen atoms
ISIS PHARMACEUTICALS INC54 citations96
US6214551B1Apr 10, 2001
Oligonucleoside linkages containing adjacent nitrogen atoms
ISIS PHARMACEUTICALS INC20 citations93
US6025482AFeb 15, 2000
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
ISIS PHARMACEUTICALS INC17 citations93
US5969118AOct 19, 1999
Backbone modified oligonucleotide analogs and preparation thereof through radical coupling
ISIS PHARMACEUTICALS INC18 citations93
US5783682AJul 21, 1998
Oligonucleotide mimics having nitrogen-containing linkages
ISIS PHARMACEUTICALS INC33 citations93
US6809195B1Oct 26, 2004
Process for the preparation of oligonucleotides
ISIS PHARMACEUTICALS INC29 citations92
US5698391ADec 16, 1997
Methods for synthetic unrandomization of oligomer fragments
ISIS PHARMACEUTICALS INC36 citations92
US6822089B1Nov 23, 2004
Preparation of deoxynucleosides
ISIS PHARMACEUTICALS INC7 citations74
US6271357B1Aug 7, 2001
Oligonucleotide mimics having nitrogen-containing linkages
ISIS PHARMACEUTICALS INC6 citations74
US6239220B1May 29, 2001
Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis
ISIS PHARMACEUTICALS INC5 citations74
US6121433ASep 19, 2000
Oligomeric compounds having nitrogen-containing linkages
ISIS PHARMACEUTICALS INC8 citations74
US6642367B2Nov 4, 2003
Process for the synthesis of 2′-O-substituted pyrimidines and oligomeric compounds therefrom
ISIS PHARMACEUTICALS INC6 citations73
US6800751B2Oct 5, 2004
Reagent and process for protecting nucleoside hydroxyl groups
ISIS PHARMACEUTICALS INC8 citations72
US6677120B2Jan 13, 2004
Building blocks for the solution phase synthesis of oligonucleotides
ISIS PHARMACEUTICALS INC6 citations64
US6124484ASep 26, 2000
Recovery of triarylmethyl halide protecting groups cleaved during oligonucleotide synthesis
ISIS PHARMACEUTICALS INC2 citations63
US6541626B2Apr 1, 2003
Process for selective N-acylation of purine nucleosides
ISIS PHARMACEUTICALS INC5 citations55