Inventor

OPALKA JR CHESTER J

27 patents

Patents

27 patents

US4309537AJan 5, 1982

Production of imidazo[4,5-b]pyridin-2-ones or thiones

STERLING DRUG INC53 citations96

US4294837AOct 13, 1981

1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use

STERLING DRUG INC59 citations96

US4107315AAug 15, 1978

5-(Pyridinyl)-2(1H)-pyridinones

STERLING DRUG INC38 citations96

US4072746AFeb 7, 1978

3-Amino-5-(pyridinyl)-2(1H)-pyridinones

STERLING DRUG INC61 citations96

US4312875AJan 26, 1982

5-(Pyridinyl)-6-(lower-alkyl)-2(1H)-pyridinones, 1,2-dihydro-2-oxo-5-(pyridinyl)-6-(lower-alkyl)nicotinic acids and lower-alkyl esters thereof, and cardiotonic use thereof

STERLING DRUG INC19 citations82

US4276293AJun 30, 1981

5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use

STERLING DRUG INC13 citations74

US4271168AJun 2, 1981

Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones

STERLING DRUG INC7 citations74

US4225715ASep 30, 1980

Preparation of 3-amino(or carbamyl)-5-(pyridinyl)-2(1H)-pyridinones

STERLING DRUG INC9 citations74

US4225601ASep 30, 1980

3-Hydroxy or hydroxymethyl-5-(4-pyridinyl)2(1H)-pyridinones, useful as cardiotonic agents and their preparation

STERLING DRUG INC11 citations74

US4223149ASep 16, 1980

Process for producing 3-cyano-5-(pyridinyl)-2(1H)-pyridinones

STERLING DRUG INC8 citations74

US4104385AAug 1, 1978

Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates

STERLING DRUG INC11 citations74

US4755595AJul 5, 1988

Enhanced production of 4,5-unsaturated steroids utilizing methanol solvation

STERLING DRUG INC6 citations73

US4599423AJul 8, 1986

Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones

STERLING DRUG INC13 citations72

US4465686AAug 14, 1984

5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation

STERLING DRUG INC17 citations72

US4684636AAug 4, 1987

Antiandrogenic sulfonylsteroidopyrazoles and processes for preparation method of use and compositions thereof

STERLING DRUG INC10 citations71

US4559352ADec 17, 1985

1,2-Dihydro-2-oxo-5-(hydroxy-and/or amino-phenyl)-nicotinonitriles and cardiotonic use thereof

STERLING DRUG INC3 citations63

US4515797AMay 7, 1985

3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof

STERLING DRUG INC3 citations63

US4463008AJul 31, 1984

2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof

STERLING DRUG INC5 citations63

US4420617ADec 13, 1983

5(Pyridinyl)pyridin-2-amines

STERLING DRUG INC2 citations63

US4374141AFeb 15, 1983

2-Substituted amino-5-(pyridinyl)-nicotinamides and their cardiotonic use

STERLING DRUG INC4 citations63

US4362734ADec 7, 1982

2-(Substituted-amino)-5-(pyridinyl-nicotinonitriles, and their cardiotonic use

STERLING DRUG INC4 citations63

US4331672AMay 25, 1982

5-(Pyridinyl)pyridine-2-hydrazines, their preparation and their cardiotonic use

STERLING DRUG INC3 citations63

US4351941ASep 28, 1982

Pyridinyl-pyridines

STERLING DRUG INC0 citations52

US4264609AApr 28, 1981

N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic

STERLING DRUG INC1 citations51

OPALKA JR CHESTER J

Patents

Production of imidazo[4,5-b]pyridin-2-ones or thiones

1,3-Dihydro-6-(pyridinyl)-2H-imidazo[4,5-b]pyridin-2-ones and -imidazo[4,5-b]pyridine-2-thiones and their cardiotonic use

5-(Pyridinyl)-2(1H)-pyridinones

3-Amino-5-(pyridinyl)-2(1H)-pyridinones

5-(Pyridinyl)-6-(lower-alkyl)-2(1H)-pyridinones, 1,2-dihydro-2-oxo-5-(pyridinyl)-6-(lower-alkyl)nicotinic acids and lower-alkyl esters thereof, and cardiotonic use thereof

Compositions and their preparation

1,2-Dihydro-2-oxo-5-(pyridinyl)nicotinamides

2-Amino-6-(pyridinyl)-3H-imidazo[4,5-b]pyridines and their cardiotonic use

5-(Pyridinyl)pyridine-2,3-diamines, preparation thereof and their cardiotonic use

Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones

Preparation of 3-amino(or carbamyl)-5-(pyridinyl)-2(1H)-pyridinones

3-Hydroxy or hydroxymethyl-5-(4-pyridinyl)2(1H)-pyridinones, useful as cardiotonic agents and their preparation

Process for producing 3-cyano-5-(pyridinyl)-2(1H)-pyridinones

Cyclic alkylidenyl N-[6-(amino)-3-pyridazinyl]aminomethylenemalonates

Enhanced production of 4,5-unsaturated steroids utilizing methanol solvation

Preparation of 5-(hydroxy- and/or aminophenyl-6-lower-alkyl)-2(1H)-pyridinones

5-(Hydroxy- and/or amino-phenyl)-6-(lower-alkyl)-2-(1H)-pyridinones, their cardiotonic use and preparation

Antiandrogenic sulfonylsteroidopyrazoles and processes for preparation method of use and compositions thereof

1,2-Dihydro-2-oxo-5-(hydroxy-and/or amino-phenyl)-nicotinonitriles and cardiotonic use thereof

3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof

2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof

5(Pyridinyl)pyridin-2-amines

2-Substituted amino-5-(pyridinyl)-nicotinamides and their cardiotonic use

2-(Substituted-amino)-5-(pyridinyl-nicotinonitriles, and their cardiotonic use

5-(Pyridinyl)pyridine-2-hydrazines, their preparation and their cardiotonic use

Pyridinyl-pyridines

N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4&#39;-bipyridin]-6(1H)-one and its use as a cardiotonic

N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic