Inventor
SCHEULE RONALD K
US18 patents
Patents
18 patentsUS5783565AJul 21, 1998
Cationic amphiphiles containing spermine or spermidine cationic group for intracellular delivery of therapeutic molecules
GENZYME CORP123 citations99
US5948767ASep 7, 1999
Cationic amphiphile/DNA complexes
GENZYME CORP271 citations98
US5719131AFeb 17, 1998
Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules
GENZYME CORP119 citations98
US6071890AJun 6, 2000
Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
GENZYME CORP128 citations97
US5840710ANov 24, 1998
Cationic amphiphiles containing ester or ether-linked lipophilic groups for intracellular delivery of therapeutic molecules
GENZYME CORP51 citations95
US5935936AAug 10, 1999
Compositions comprising cationic amphiphiles and co-lipids for intracellular delivery of therapeutic molecules
GENZYME CORP85 citations94
US8003617B2Aug 23, 2011
Methods of treating diabetes mellitus
GENZYME CORP27 citations92
US6383814B1May 7, 2002
Cationic amphiphiles for intracellular delivery of therapeutic molecules
GENZYME CORP32 citations92
US5939401AAug 17, 1999
Cationic amphiphile compositions for intracellular delivery of therapeutic molecules
GENZYME CORP37 citations92
US5910487AJun 8, 1999
Cationic amphiphiles and plasmids for intracellular delivery of therapeutic molecules
GENZYME CORP28 citations92
US5747471AMay 5, 1998
Cationic amphiphiles containing steroid lipophilic groups for intracellular delivery of therapeutic molecules
GENZYME CORP37 citations92
US9532976B2Jan 3, 2017
Method of lowering blood glucose
GENZYME CORP5 citations83
US11008316B2May 18, 2021
Glucosylceramide synthase inhibitors
GENZYME CORP6 citations81
US6331524B1Dec 18, 2001
Organ-specific targeting of cationic amphiphile / DNA complexes for gene therapy
GENZYME CORP11 citations72
US12060349B2Aug 13, 2024
Glucosylceramide synthase inhibitors
GENZYME CORP1 citations59
US11801311B2Oct 31, 2023
Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides
GENZYME CORP0 citations58
US6465007B1Oct 15, 2002
Transgene expression in polarized cells
GENZYME CORP6 citations56
US10682423B2Jun 16, 2020
Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides
GENZYME CORP0 citations48