Inventor
CHENG SENG H
US60 patents
⚠️ This page may combine multiple inventors who share the name “CHENG SENG H”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
GENZYME CORP
31 patentsUS5783565AJul 21, 1998
Cationic amphiphiles containing spermine or spermidine cationic group for intracellular delivery of therapeutic molecules
GENZYME CORP123 citations99
US5948767ASep 7, 1999
Cationic amphiphile/DNA complexes
GENZYME CORP271 citations98
US5719131AFeb 17, 1998
Cationic amphiphiles containing dialkylamine lipophilic groups for intracellular delivery of therapeutic molecules
GENZYME CORP119 citations98
US6071890AJun 6, 2000
Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
GENZYME CORP128 citations97
US5650096AJul 22, 1997
Cationic amphiphiles for intracellular delivery of therapeutic molecules
GENZYME CORP92 citations96
US7910545B2Mar 22, 2011
Combination enzyme replacement and small molecule therapy for treatment of lysosomal storage diseases
GENZYME CORP42 citations95
US6066626AMay 23, 2000
Compositions and method for treating lysosomal storage disease
GENZYME CORP154 citations95
US5840710ANov 24, 1998
Cationic amphiphiles containing ester or ether-linked lipophilic groups for intracellular delivery of therapeutic molecules
GENZYME CORP51 citations95
US10369193B2Aug 6, 2019
Gene therapy for neurodegenerative disorders
GENZYME CORP17 citations94
US5981714ANov 9, 1999
Antibodies specific for cystic fibrosis transmembrane conductance regulator and uses therefor
GENZYME CORP53 citations94
US5935936AAug 10, 1999
Compositions comprising cationic amphiphiles and co-lipids for intracellular delivery of therapeutic molecules
GENZYME CORP85 citations94
US9415119B2Aug 16, 2016
Gene therapy for neurodegenerative disorders
GENZYME CORP13 citations92
US8003617B2Aug 23, 2011
Methods of treating diabetes mellitus
GENZYME CORP27 citations92
US7658916B2Feb 9, 2010
Methods of enhancing lysosomal storage disease therapy by modulation of cell surface receptor density
GENZYME CORP43 citations92
US6383814B1May 7, 2002
Cationic amphiphiles for intracellular delivery of therapeutic molecules
GENZYME CORP32 citations92
US5981275ANov 9, 1999
Transgene expression system for increased persistence
GENZYME CORP27 citations92
US5939401AAug 17, 1999
Cationic amphiphile compositions for intracellular delivery of therapeutic molecules
GENZYME CORP37 citations92
US5910487AJun 8, 1999
Cationic amphiphiles and plasmids for intracellular delivery of therapeutic molecules
GENZYME CORP28 citations92
US5747471AMay 5, 1998
Cationic amphiphiles containing steroid lipophilic groups for intracellular delivery of therapeutic molecules
GENZYME CORP37 citations92
US11911440B2Feb 27, 2024
Gene therapy for neurodegenerative disorders
GENZYME CORP5 citations86
US10907142B2Feb 2, 2021
Oligosaccharides comprising an aminooxy group and conjugates thereof
GENZYME CORP4 citations84
US10080783B2Sep 25, 2018
Intraventricular enzyme delivery for lysosomal storage diseases
GENZYME CORP6 citations84
US9469850B2Oct 18, 2016
Oligosaccharides comprising an aminooxy group and conjugates thereof
GENZYME CORP6 citations84
US9532976B2Jan 3, 2017
Method of lowering blood glucose
GENZYME CORP5 citations83
US10821154B2Nov 3, 2020
Compositions and methods for treating spinal muscular atrophy
GENZYME CORP7 citations82
US11008316B2May 18, 2021
Glucosylceramide synthase inhibitors
GENZYME CORP6 citations81
US11975043B2May 7, 2024
Gene therapy for neurodegenerative disorders
GENZYME CORP3 citations75
US6331524B1Dec 18, 2001
Organ-specific targeting of cationic amphiphile / DNA complexes for gene therapy
GENZYME CORP11 citations72
US9556155B2Jan 31, 2017
Methods of treating fatty liver disease
GENZYME CORP3 citations71
US6323191B1Nov 27, 2001
Small molecule chloride transport
GENZYME CORP10 citations71
US11253485B2Feb 22, 2022
Slow intraventricular delivery
GENZYME CORP4 citations68
IONIS PHARMACEUTICALS INC
5 patentsUS9683236B2Jun 20, 2017
Modulation of huntingtin expression
IONIS PHARMACEUTICALS INC5 citations84
US11421231B2Aug 23, 2022
Modulation of Huntington expression
IONIS PHARMACEUTICALS INC1 citations73
US10837016B2Nov 17, 2020
Modulation of huntingtin expression
IONIS PHARMACEUTICALS INC2 citations73
US10619158B2Apr 14, 2020
Modulation of huntingtin expression
IONIS PHARMACEUTICALS INC2 citations73
US10202603B2Feb 12, 2019
Modulation of huntingtin expression
IONIS PHARMACEUTICALS INC2 citations73
ISIS PHARMACEUTICALS INC
2 patentsDODGE JAMES
2 patentsBENNETT C FRANK
1 patentBIOGEN MA INC
1 patentZHAO HONGMEI
1 patentHUNG GENE
1 patentSCHLOSSMACHER MICHAEL
1 patentZHU YUNXIANG
1 patentBRIGHAM & WOMENS HOSPITAL INC
1 patentMEEKER DAVID
1 patentSANOFI SA
1 patentNATOLI THOMAS A
1 patentShowing the top 50 of 60 patents by PatentIndex Score.