Inventor · disambiguated record
Roger F. Bone
Also filed as: BONE ROGER · BONE ROGER F · BONE ROGER FRANCIS
24 granted patents·11 pending applications·1,534 citations·filing 1994–2024
97Inventor score
Files withDIMENSIONAL PHARM INC17JANSSEN PHARMACEUTICA NV5LEONARD KRISTI A3BONE ROGER F2ORTHO MCNEIL PHARM INC2
Top patents by PatentIndex Score
35 records- 0199US5463564ASystem and method of automatically generating chemical compounds with desired propertiesDIMENSIONAL PHARM INC·Filed 1994·Granted Oct 31, 1995·389 cites·64 claims
- 0297US6434490B1Method of generating chemical compounds having desired propertiesDIMENSIONAL PHARM INC·Filed 1998·Granted Aug 13, 2002·91 cites·5 claims
- 0397US6036920AMicroplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimizationDIMENSIONAL PHARM INC·Filed 1997·Granted Mar 14, 2000·153 cites·43 claims
- 0496US6421612B1System, method and computer program product for identifying chemical compounds having desired propertiesDIMENSIONAL PHARM INC·Filed 1997·Granted Jul 16, 2002·159 cites·42 claims
- 0596US5684711ASystem, method, and computer program for at least partially automatically generating chemical compounds having desired propertiesDIMENSIONAL PHARM INC·Filed 1996·Granted Nov 4, 1997·153 cites·54 claims
- 0696US5574656ASystem and method of automatically generating chemical compounds with desired propertiesDIMENSIONAL PHARM INC·Filed 1995·Granted Nov 12, 1996·182 cites·2 claims
- 0795US5901069ASystem, method, and computer program product for at least partially automatically generating chemical compounds with desired properties from a list of potential chemical compounds to synthesizeDIMENSIONAL PHARM INC·Filed 1997·Granted May 4, 1999·123 cites·18 claims
- 0893US6214293B1Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimizationDIMENSIONAL PHARM INC·Filed 1999·Granted Apr 10, 2001·70 cites·26 claims
- 0986US6515002B2Compounds and compositions for treating C1s-mediated diseases and conditionsDIMENSIONAL PHARM INC·Filed 2001·Granted Feb 4, 2003·26 cites·13 claims
- 1086US2025288584A1Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their useJANSSEN PHARMACEUTICA NV·Filed 2024·Application pending·0 cites
- 1185US6326492B1Heterocyclic protease inhibitorsDIMENSIONAL PHARM INC·Filed 2000·Granted Dec 4, 2001·25 cites·41 claims
- 1285US6268218B1Method for sensing and processing fluorescence data from multiple samplesDIMENSIONAL PHARM INC·Filed 1999·Granted Jul 31, 2001·37 cites·25 claims
- 1385US2025041301A1Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their useJANSSEN PHARMACEUTICA NV·Filed 2024·Application pending·0 cites
- 1483US6492403B1Methods of treating C1s-mediated diseases and conditions and compositions thereofDIMENSIONAL PHARM INC·Filed 2000·Granted Dec 10, 2002·22 cites·27 claims
- 1582US6849458B2Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimizationFiled 2001·Granted Feb 1, 2005·11 cites·7 claims
- 1681US5792769AGuanidino protease inhibitors3-DIMENSIONAL PHARM INC·Filed 1996·Granted Aug 11, 1998·34 cites·49 claims
- 1780US7030110B2Cyclic oxyguanidine pyrazinones as protease inhibitorsORTHO MCNEIL PHARM INC·Filed 2002·Granted Apr 18, 2006·8 cites·28 claims
- 1880US6476016B2Cyclic oxyguanidine pyrazinones as protease inhibitorsDIMENSIONAL PHARM INC·Filed 2001·Granted Nov 5, 2002·12 cites·25 claims
- 1979US11369606B2Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their useJANSSEN PHARMACEUTICA NV·Filed 2019·Granted Jun 28, 2022·1 cites·20 claims
- 2078US7482376B2Conjugated complement cascade inhibitorsDIMENSIONAL PHARM INC·Filed 2004·Granted Jan 27, 2009·11 cites·11 claims
- 2176US6635637B2Cyclic oxyguanidine protease inhibitorsDIMENSIONAL PHARM INC·Filed 2001·Granted Oct 21, 2003·9 cites·50 claims
- 2275US2022143141A1Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their useJANSSEN PHARMACEUTICA NV·Filed 2021·Application pending·0 cites
- 2371US10537573B2Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their useJANSSEN PHARMACEUTICA NV·Filed 2015·Granted Jan 21, 2020·1 cites·20 claims
- 2463US8883473B2Methods of treatment using allosteric processing inhibitors for matrix metalloproteinasesLEONARD KRISTI A·Filed 2012·Granted Nov 11, 2014·1 cites·14 claims
- 2559US2006058291A1Cyclic oxyguanidine pyrazinones as protease inhibitorsORTHO MCNEIL PHARM INC·Filed 2005·Application pending·0 cites
- 2657US5612369AThrombin inhibitorsDIMENSIONAL PHARM INC·Filed 1995·Granted Mar 18, 1997·16 cites·14 claims
- 2755US2004185504A1Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimizationFiled 2004·Application pending·0 cites
- 2853US2003203497A1Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimizationFiled 2003·Application pending·0 cites
- 2950US8798939B2Methods for designing, selecting and/or optimizing allosteric processing inhibitors for matrix metalloproteinasesLEONARD KRISTI A·Filed 2012·Granted Aug 5, 2014·0 cites·4 claims
- 3046US2003033088A1Method of generating chemical compounds having desired propertiesFiled 2002·Application pending·0 cites
- 3145US2003014191A1System, method and computer program product for identifying chemical compounds having desired propertiesDIMENSIONAL PHARM INC·Filed 2002·Application pending·0 cites
- 3243US2006099643A1Method for determining the regulation of xenobiotic removalBONE ROGER F·Filed 2003·Application pending·0 cites
- 3339US2006110732A1Method for the identification of ligandsBONE ROGER F·Filed 2003·Application pending·0 cites
- 3438US8753857B2Crystal structure of the pro form of a matrix metalloproteinase and an allosteric processing inhibitorLEONARD KRISTI A·Filed 2012·Granted Jun 17, 2014·0 cites·4 claims
- 3538US2006024844A1Method for the idenification of ligandsRENTZEPERIS DIONISIOS·Filed 2002·Application pending·0 cites
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