Inventor
ORWAT MICHAEL J
US35 patents
⚠️ This page may combine multiple inventors who share the name “ORWAT MICHAEL J”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
BRISTOL MYERS SQUIBB CO
27 patentsUS8367709B2Feb 5, 2013
Dipeptide analogs as coagulation factor inhibitors
BRISTOL MYERS SQUIBB CO42 citations94
US9453018B2Sep 27, 2016
Pyrimidinones as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO13 citations92
US7312214B2Dec 25, 2007
1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors
BRISTOL MYERS SQUIBB CO58 citations90
US9192607B2Nov 24, 2015
Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO7 citations84
US9108951B2Aug 18, 2015
Substituted 5,6,7,8-tetrahydro-1,6-naphthyridines as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO5 citations84
US9000172B2Apr 7, 2015
Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO7 citations84
US7371761B2May 13, 2008
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
BRISTOL MYERS SQUIBB CO12 citations83
US9944625B2Apr 17, 2018
Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO3 citations73
US11053247B2Jul 6, 2021
Pyrimidinones as factor XIA inhibitors
BRISTOL MYERS SQUIBB CO2 citations72
US10336754B2Jul 2, 2019
Pyrimidinones as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO2 citations72
US9777001B2Oct 3, 2017
Macrocycles with aromatic P2′ groups as factor xia inhibitors
BRISTOL MYERS SQUIBB CO3 citations72
US7371864B2May 13, 2008
Crystalline forms of a factor Xa inhibitor
BRISTOL MYERS SQUIBB CO7 citations71
US12428421B2Sep 30, 2025
Pyrimidinones as factor XIA inhibitors
BRISTOL MYERS SQUIBB CO0 citations62
US10676477B2Jun 9, 2020
Factor XIa macrocycle inhibitors bearing a non-aromatic P2' group
BRISTOL MYERS SQUIBB CO2 citations62
US10000466B2Jun 19, 2018
Substituted 4,5,6,7-tetrahydropyrazolo[3,4-c]pyridines as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO1 citations62
US9447110B2Sep 20, 2016
Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO1 citations62
US10611776B2Apr 7, 2020
Spiroheptane salicylamides and related compounds as inhibitors of rock
BRISTOL MYERS SQUIBB CO1 citations61
US11306081B2Apr 19, 2022
Phenylacetamides as inhibitors of rock
BRISTOL MYERS SQUIBB CO0 citations52
US10208021B2Feb 19, 2019
Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO0 citations52
US9725435B2Aug 8, 2017
Substituted 4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO0 citations52
US9394276B2Jul 19, 2016
Substituted 1,2,3,4-tetrahydro-2,6-naphthyridines as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO0 citations52
US10829501B2Nov 10, 2020
Spiroheptane salicylamides and related compounds as inhibitors of ROCK
BRISTOL MYERS SQUIBB CO0 citations50
US9738655B2Aug 22, 2017
Tetrahydroisoquinolines containing substituted azoles as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO1 citations49
US9403774B2Aug 2, 2016
Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors
BRISTOL MYERS SQUIBB CO0 citations42
US9315519B2Apr 19, 2016
Guanidine substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO0 citations42
US10273236B2Apr 30, 2019
Macrocyclic factor XIa inhibitors bearing heterocyclic groups
BRISTOL MYERS SQUIBB CO0 citations41
US9079929B2Jul 14, 2015
Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors
BRISTOL MYERS SQUIBB CO0 citations41
BRISTOL MYERS SQUIBB PHARMA CO
4 patentsUS6967208B2Nov 22, 2005
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
BRISTOL MYERS SQUIBB PHARMA CO100 citations98
US6989391B2Jan 24, 2006
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
BRISTOL MYERS SQUIBB PHARMA CO59 citations95
US6995172B2Feb 7, 2006
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
BRISTOL MYERS SQUIBB PHARMA CO19 citations93
US7005435B2Feb 28, 2006
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
BRISTOL MYERS SQUIBB PHARMA CO19 citations92
DU PONT MERCK PHARMA
4 patentsUS5593994AJan 14, 1997
Prostaglandin synthase inhibitors
DU PONT MERCK PHARMA251 citations98
US5428040AJun 27, 1995
Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
DU PONT MERCK PHARMA10 citations73
US5585382ADec 17, 1996
Polycyclic and heterocyclic chromophores for bis-imide tumoricidals
DU PONT MERCK PHARMA7 citations71
US5416089AMay 16, 1995
Polycyclic and heterocyclic chromophores for bis-imide tumoricidals
DU PONT MERCK PHARMA12 citations71