Inventor

SLETZINGER MEYER

35 patents

Patents

35 patents

US4582915AApr 15, 1986

Process for C-methylation of 2-methylbutyrates

MERCK & CO INC61 citations96

US4611067ASep 9, 1986

Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein

MERCK & CO INC57 citations95

US4292436ASep 29, 1981

Process for the preparation of N-protected N-formimidoyl 2-aminoethanethiol

MERCK & CO INC38 citations92

US4297488AOct 27, 1981

7-α-Methoxy cephalosporins

MERCK & CO INC25 citations82

US4287123ASep 1, 1981

Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate

MERCK & CO INC24 citations82

US4282148AAug 4, 1981

Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid

MERCK & CO INC28 citations82

US4645854AFeb 24, 1987

Process for preparing HMG-CoA reductase inhibitors with a 3,5-dihydroxypentanoate subunit

MERCK & CO INC22 citations81

US4620025AOct 28, 1986

Process for the preparation of biphenyl intermediates

MERCK & CO INC13 citations74

US4584389AApr 22, 1986

Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

MERCK & CO INC9 citations74

US4338437AJul 6, 1982

Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid

MERCK & CO INC9 citations73

US4467107AAug 21, 1984

1-Hydroxyethyl-2-amino pentanedioic acid derivatives

MERCK & CO INC6 citations73

US4414155ANov 8, 1983

Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid

MERCK & CO INC10 citations73

US4349687ASep 14, 1982

Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid

MERCK & CO INC9 citations73

US4344885AAug 17, 1982

Intermediate for the preparation of thienamycin

MERCK & CO INC9 citations73

US4329481AMay 11, 1982

Process for the preparation of N-protected N-formimidoyl 2-aminoethanethiol

MERCK & CO INC14 citations73

US4360684ANov 23, 1982

Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid

MERCK & CO INC10 citations70

US4343937AAug 10, 1982

3-Substituted-7-methoxy-7-amino-3-cephem-4-carboxylic acids

MERCK & CO INC3 citations63

US4338438AJul 6, 1982

Cephalosporin antibiotics

MERCK & CO INC2 citations63

US4582914AApr 15, 1986

Process for the preparation of HMG-CoA reductase inhibitors

MERCK & CO INC3 citations62

US4454332AJun 12, 1984

Hydroxy amino dicarboxylic acids and esters

MERCK & CO INC3 citations62

US4299974ANov 10, 1981

Process for preparing N-protected 2-aminoethanethiol

MERCK & CO INC6 citations62

US4149012AApr 10, 1979

Synthesis of racemic 3-fluoro-alanine and its salts

MERCK & CO INC2 citations61

US3981911ASep 21, 1976

Process for preparing (1-oxo-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid

MERCK & CO INC4 citations61

US3972921AAug 3, 1976

Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

MERCK & CO INC5 citations61

US3987040AOct 19, 1976

3-substituted methyl-7-acylamino-7-methoxy-2-cephem-4-carboxylic acid and its esters

MERCK & CO INC3 citations58

US4393242AJul 12, 1983

Process for preparing methylvanillyl ketone from isoeugenol

MERCK & CO INC1 citations52

US4342757AAug 3, 1982

Cephalosporin antibiotic compositions

MERCK & CO INC1 citations52

US4337360AJun 29, 1982

Process for preparing methylvanillyl ketone from isoeugenol

MERCK & CO INC0 citations52

US4342869AAug 3, 1982

Cephalosporin antibiotics

MERCK & CO INC0 citations42

SLETZINGER MEYER

Patents

Process for C-methylation of 2-methylbutyrates

Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein

Process for the preparation of N-protected N-formimidoyl 2-aminoethanethiol

7-α-Methoxy cephalosporins

Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate

Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid

Process for preparing HMG-CoA reductase inhibitors with a 3,5-dihydroxypentanoate subunit

Process for the preparation of biphenyl intermediates

Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

Cephalosporin antibiotics

Cephalosporin intermediates

7-Diacylimido cephalosporins

7-Diacyl cephalosporins

Process for the production of 7-acylamidocephalosporins

Process for the preparation of chloromethyl methyl ether

Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid

1-Hydroxyethyl-2-amino pentanedioic acid derivatives

Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid

Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid

Intermediate for the preparation of thienamycin

Process for the preparation of N-protected N-formimidoyl 2-aminoethanethiol

Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid

3-Substituted-7-methoxy-7-amino-3-cephem-4-carboxylic acids

Cephalosporin antibiotics

Process for the preparation of HMG-CoA reductase inhibitors

Hydroxy amino dicarboxylic acids and esters

Process for preparing N-protected 2-aminoethanethiol

Synthesis of racemic 3-fluoro-alanine and its salts

Process for preparing (1-oxo-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxy)acetic acid

Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts

3-substituted methyl-7-acylamino-7-methoxy-2-cephem-4-carboxylic acid and its esters

Process for preparing methylvanillyl ketone from isoeugenol

Cephalosporin antibiotic compositions

Process for preparing methylvanillyl ketone from isoeugenol

Cephalosporin antibiotics