Inventor

SZARKA LASZLO J

US33 patents

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SZARKA LASZLO J

SQUIBB & SONS INC

Enzymatic processes for resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes

Lipase esterification processes for resolution of enantiomeric mixtures of intermediates in the preparation of taxanes

Enzymatic reduction method for the preparation of compounds useful for preparing taxanes

Enzymatic reduction method for the preparation of compounds useful for preparing taxanes

Stereoselective preparation of halophenyl alcohols from ketones

Enzymatic hydrolysis and esterification processes for the preparation of HMG-CoA reductase inhibitors and intermediates thereof

Microbial reduction of benzazepines and benzothiazepine derivatives

Enzymatic process for enantiomer-specific perparation of mercapto alkanoic acid compounds

Microbiological hydrolysis for the preparation of (exo,exo)-7-oxabicyclo(2.2.1) heptane-2,3, monoacyl ester dimethanol

Process for selecting an enantiomer of a hydroxy lactone using pseudomonas lipase

Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters

Process for separation of enantiomeric 3-mercapto-2-substituted alkanoic acid using lipase P30 and synthesis of captopril type compounds

Method of preparing D(-)-β-hydroxyisobutyric acid by fermentation

Use of phenoxyalkanes as precursors in penicillin V fermentation

Method for forming amphotericin B crystals in fermentation broth

Enantioselective preparation of halophenyl alcohols and acylates

Enzymatic resolution process

Enzymatic resolution process hydrolyzing thio-ester

Use of phenylalkanes as precursors in benzylpenicillin fermentation

BRISTOL MYERS SQUIBB CO

Enzymatic hydrolysis method for the conversion of C-7 sugar to C-7 hydroxyl taxanes

Stereoselective reduction of ketones

Stereoselective reductive amination of ketones

Enzymatic hydrolysis method for the preparation of C-13 hydroxyl-bearing taxanes, and use thereof in the preparation of C-13 acyloxy-bearing taxanes

Enzymatic hydrolysis method for the preparation of C-10 hydroxyl-bearing taxanes and enzymatic esterification method for the preparation of C-10 acyloxy-bearing

Preparation of C-13 hydroxyl-bearing taxanes using nocardioides or a hydrolase isolated therefrom

Enzymatic oxidative deamination process

Enzymatic reduction method for the preparation of halohydrins

Stereoselective reductive amination of ketones

Method of chiral epoxidation of benzopyran or pyranopyridine derivatives using microorganisms

Process for preparing an optically pure intermediate for a phosphonosulfonate soualene synthetase inhibitor

Enzymatic oxidative deamination process

Enzymatic methods for the preparation of pradimicins

PATEL RAMESH N

(Exo,exo)-7-oxabicyclo[2.2.1]heptane-2,3-dimethanol; monoacyl ester and diacyl ester