Inventor
PAPPO RAPHAEL
30 patents
⚠️ This page may combine multiple inventors who share the name “PAPPO RAPHAEL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SEARLE & CO
24 patentsUS3965143AJun 22, 1976
16-Oxygenated prostanoic acid derivatives
SEARLE & CO70 citations96
US4348388ASep 7, 1982
11-Amino-11-deoxydaunorubicin and analogs
SEARLE & CO18 citations80
US4271314AJun 2, 1981
4,5-Unsaturated prostanoic acid derivatives
SEARLE & CO14 citations74
US3991061ANov 9, 1976
Azanaphthaleneacetic acid derivatives
SEARLE & CO9 citations74
US4540801ASep 10, 1985
5 Fluoro PGI compounds
SEARLE & CO9 citations72
US4003996AJan 18, 1977
Spirolactone for inhibiting the cardiotoxic effects of adriamycin
SEARLE & CO10 citations66
US4322543AMar 30, 1982
4,5-Unsaturated prostanoic acid derivatives
SEARLE & CO5 citations63
US4087621AMay 2, 1978
7-{3-Hydroxy-2β-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1α-yl}hept-5-cis-enoic acids and related compounds
SEARLE & CO4 citations63
US4087447AMay 2, 1978
Anti-secretory prostaglandins intermediates
SEARLE & CO4 citations63
US4064350ADec 20, 1977
15,16-Dihydroxyprostaglandins
SEARLE & CO4 citations63
US4060691ANov 29, 1977
7-{3-Hydroxy-2-[4-hydroxy-4-(lower alkyl)-trans-1-octen-1-yl]-5-oxocyclopent-1-yl}heptanoic acids and esters
SEARLE & CO4 citations63
US3970683AJul 20, 1976
11,15-Dihydroxy-9-oxoprost-13-ynoic acid
SEARLE & CO2 citations63
US4670569AJun 2, 1987
5-fluoro-PGI2 compounds
SEARLE & CO4 citations61
US4275192AJun 23, 1981
Bis(4-demethoxydaunorubicin)dihydrazone derivatives and pharmacologically acceptable salts thereof
SEARLE & CO4 citations61
US3969391AJul 13, 1976
Preparation of prostaglandin precursors
SEARLE & CO4 citations61
US3932496AJan 13, 1976
Mono- and dialkylated prostynoic acid derivatives
SEARLE & CO5 citations61
US4328355AMay 4, 1982
Prostaglandin derivatives having aryl, hydroxyl, and alkynyl functions in one side chain
SEARLE & CO1 citations52
US4149006AApr 10, 1979
Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
SEARLE & CO0 citations52
US4053476AOct 11, 1977
7-aza-6-alkoxy-1-tetralones
SEARLE & CO0 citations52
US4012391AMar 15, 1977
11β-Alkyl-2-azaestratrienes and intermediates
SEARLE & CO0 citations52
US4007194AFeb 8, 1977
Process and intermediates for manufacture of 2-azasterioids
SEARLE & CO0 citations52
US3962291AJun 8, 1976
Total synthesis of 11-alkyl steroids
SEARLE & CO1 citations52
US4223158ASep 16, 1980
2,3,5-Trisubstituted cyclopentanealkenoic acids, derivatives thereof and intermediates thereto
SEARLE & CO0 citations47
US4029689AJun 14, 1977
7-(3(S)-Hydroxy-5-oxocyclopent-1-ene)hept-5-cis-enoic acid, esters thereof and derivatives
SEARLE & CO0 citations47
SEARLE G D &
3 patentsUS4161480AJul 17, 1979
Intermediates for the synthesis of 4-demethoxydaunorubicin
SEARLE G D &9 citations73
US4151187AApr 24, 1979
Intermediates for prostaglandin synthesis
SEARLE G D &1 citations52
US4172953AOct 30, 1979
2,3,5-Trisubstituted cyclopentanealkenoic acids, derivatives thereof and intermediates thereto
SEARLE G D &1 citations47