P

Inventor

MARBURG STEPHEN

US18 patents

Patents

18 patents
US4882317ANov 21, 1989

Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency

MERCK & CO INC148 citations98
US4695624ASep 22, 1987

Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency

MERCK & CO INC202 citations98
US5623057AApr 22, 1997

Pneumococcal polysaccharide conjugate vaccine

MERCK & CO INC173 citations96
US5057517AOct 15, 1991

Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents

MERCK & CO INC83 citations96
US4830852AMay 16, 1989

Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins and methods of preparing such polysaccharides and conjugates

MERCK & CO INC95 citations93
US5371197ADec 6, 1994

Protein-dimeric polysaccharide conjugate vaccine

MERCK & CO INC47 citations92
US5606030AFeb 25, 1997

Coconjugates of OMPC, HIV related peptides and anionic moieties

MERCK & CO INC18 citations83
US4488991ADec 18, 1984

Bacterial toxoids and gram-negative immune globulin therefrom

MERCK & CO INC20 citations80
US4428931AJan 31, 1984

Bacterial toxoids and gram-negative immune globulin therefrom

MERCK & CO INC25 citations80
US5274122ADec 28, 1993

Acidic derivatives of homocysteine thiolactone

MERCK & CO INC9 citations74
US4988625AJan 29, 1991

Method for determining the functionalization of a solid support

MERCK & CO INC10 citations74
US4483870ANov 20, 1984

α-Difluoromethyl amino acids and hypertension treating compositions thereof

MERCK & CO INC13 citations73
US4347374AAug 31, 1982

Acid addition salts of N-trityl-α-fluoromethylhistidine enantiomer derivatives

MERCK & CO INC12 citations66
US4292427ASep 29, 1981

Cephalosporin compounds

MERCK & CO INC2 citations62
US4288601ASep 8, 1981

Fluorination process

MERCK & CO INC5 citations62
US4210750AJul 1, 1980

Process for the preparation of 3-carbamoyl cephalosporins using isocyanates

MERCK & CO INC4 citations62
US4049708ASep 20, 1977

Fluorodesulfurization of alkyl mercaptans or alkyl dithianes

MERCK & CO INC2 citations62
US4215221AJul 29, 1980

Fluorination process

MERCK & CO INC1 citations51