Inventor

NICOLAOU KYRIACOS C

US58 patents

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NICOLAOU KYRIACOS C

SCRIPPS RESEARCH INST

Analogs of calicheamicin gamma1I, method of making and using the same

Epothilone analogs

Epothilone analogs

Saccharide intermediates in the formation of the calicheamicin and esperamicin oligosaccharides

Epothilone analogs

Daunomycin derivative with reduced cytotoxicity toward normal cells

Inhibitors of NADH:ubiquinone oxidoreductase

Epothilone analogs

Dynemicin analogs: syntheses, methods of preparation and use

Dynemicin analogs: syntheses, methods of preparation and use

Dynemicin analogs: synthesis, methods of preparation and use

Analogs of sarcodictyin and eleutherobin

Epothilone derivatives and their synthesis and use

Transformations of taxol

Water soluble onium salt of taxo-diterpenoid

Analogs of epothilone

Cyclopropyl and cyclobutyl epothilone analogs

Designed quinone- and hydroquinone-containing cyclic enediyneols and enediyneones having DNA cleaving and cytotoxic properties

Ten-membered ring enediynediols and enediynediones having DNA cleaving properties

Synthesis of non-symmetrical sulfamides using burgess-type reagents

Carbopeptoids and carbo-nucleotoids

Carbopeptoids and carbonucleotoids

Formation of esperamicin precursors

Daunomycin derivative with reduced cytotoxicity toward normal cells

Open chain enediyne dihydroperoxides having DNA cleaving properties

RESEARCH CORP

Alkanoarachidonic acids

Leukotriene analogues

Leukotriene analogues

Pharmaceutically active 6,9-thiaprostacyclin analogs and derivatives thereof

Carbocyclic thromboxane A2 analogues

Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin

Pyridoza prostacyclin analogues and N-oxides thereof

Method of preparing bicyclo(3.1.1)hept-2-one

Bicyclo aldehyde and process for preparation

Thromboxane A2 analogues

UNIV RICE WILLIAM M

Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents

Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents

Desacetoxytubulysin H and analogs thereof

Derivatives of uncialamycin, methods of synthesis and their use as antitumor agents

Total synthesis of trioxacarcin DC-45-A2 and preparation of trioxacarcin analogs

Derivatives of thailanstatin A, methods of treatment and methods of synthesis thereof

UNIV PENNSYLVANIA

Non-Peptide peptidomimetics

Glycolipids

Method of synthesizing leukotriene B4 and derivatives thereof

Cyclic conjugated enediynes

Preparation of (S,S)-secoisolariciresinol diglucoside and (R,R)-secoisolariciresinol diglucoside

SCRIPPS CLINIC RES

Phosphene oxide-terminated allene-ene-yne dna-cleaving, antitumor and antibiotic molecules

Golfomycin derivatives: fused ring cyclodecadiyne derivatives having dna-cleaving properties and antitumor activity

US AGRICULTURE

Sesquiterpene epoxides and process for their preparation

UNIV EMORY

HIF-1 inhibitors