P

Inventor

FROHN MICHAEL J

US36 patents
⚠️ This page may combine multiple inventors who share the name “FROHN MICHAEL J”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

AMGEN INC

31 patents
US11090304B2Aug 17, 2021

KRAS G12C inhibitors and methods of using the same

AMGEN INC33 citations94
US9611261B2Apr 4, 2017

Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use

AMGEN INC25 citations94
US9085576B2Jul 21, 2015

Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use

AMGEN INC31 citations94
US11766436B2Sep 26, 2023

KRAS G12C inhibitors and methods of using the same

AMGEN INC11 citations85
US9718803B2Aug 1, 2017

Unsaturated nitrogen heterocyclic compounds useful as PDE10 inhibitors

AMGEN INC8 citations84
US9303028B2Apr 5, 2016

Azetidine and piperidine compounds useful as PDE10 inhibitors

AMGEN INC4 citations84
US7635715B2Dec 22, 2009

Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof

AMGEN INC7 citations71
US12440491B2Oct 14, 2025

KRAS G12C inhibitors and methods of using the same

AMGEN INC1 citations64
US12441736B2Oct 14, 2025

KIF18A inhibitors

AMGEN INC1 citations63
US8691986B2Apr 8, 2014

Azetidine and piperidine compounds useful as PDE10 inhibitors

AMGEN INC3 citations63
US11807693B2Nov 7, 2023

Apelin polypeptides

AMGEN INC0 citations62
US8030346B2Oct 4, 2011

Heterocyclic quinolone derivatives that inhibit prolyl hydroxylase activity

AMGEN INC2 citations62
US7842685B2Nov 30, 2010

S1P1 receptor agonists and use thereof

AMGEN INC3 citations62
US12459932B2Nov 4, 2025

KIF18A inhibitors

AMGEN INC1 citations61
US10941182B2Mar 9, 2021

Apelin polypeptides

AMGEN INC0 citations61
US7728130B2Jun 1, 2010

Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity

AMGEN INC2 citations60
US12509442B2Dec 30, 2025

KIF18A inhibitors

AMGEN INC0 citations59
US12054476B2Aug 6, 2024

KIF18A inhibitors

AMGEN INC1 citations59
US8012968B2Sep 6, 2011

Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, and compositions, and uses thereof

AMGEN INC4 citations59
US11021493B2Jun 1, 2021

1,4-thiazine dioxide and 1,2,4-thiadiazine dioxide derivatives as beta-secretase inhibitors and methods of use

AMGEN INC0 citations52
US9493459B2Nov 15, 2016

Azetidine and piperidine compounds useful as PDE10 inhibitors

AMGEN INC0 citations52
US10947223B2Mar 16, 2021

Substituted oxazines as beta-secretase inhibitors

AMGEN INC0 citations51
US9550762B2Jan 24, 2017

Cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use

AMGEN INC1 citations51
US12540129B2Feb 3, 2026

KIF18A inhibitors

AMGEN INC0 citations50
US7928139B2Apr 19, 2011

Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof

AMGEN INC0 citations50
US7504403B2Mar 17, 2009

Substituted heterocyclic compounds and methods of use

AMGEN INC2 citations50
US8759532B2Jun 24, 2014

Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors

AMGEN INC0 citations49
US9328134B2May 3, 2016

Carbohydrate phosphonate derivatives as modulators of glycosylation

AMGEN INC0 citations48
US8017626B2Sep 13, 2011

Quinolone based compounds exhibiting, prolyl hydroxylase inhibitory activity, and compositions, and uses thereof

AMGEN INC1 citations48
US10889581B2Jan 12, 2021

Cyclopropyl fused thiazine derivatives as beta-secretase inhibitors and methods of use

AMGEN INC0 citations47
US10246429B2Apr 2, 2019

Vinyl fluoride cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use

AMGEN INC0 citations41

ALLEN JENNIFER R

5 patents