Inventor

JOHNSTON J O'NEAL

US15 patents

⚠️ This page may combine multiple inventors who share the name “JOHNSTON J O'NEAL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

MERRELL DOW PHARMA

14 patents

US5486511AJan 23, 1996

4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase

MERRELL DOW PHARMA31 citations91

US4322416AMar 30, 1982

10-Alkynyl steroids

MERRELL DOW PHARMA26 citations82

US4289762ASep 15, 1981

10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors

MERRELL DOW PHARMA25 citations82

US5491136AFeb 13, 1996

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase, 19-hydroxylaser inhibitors and methods of their use in the treatment of estrogen mediated disorders

MERRELL DOW PHARMA8 citations73

US5252565AOct 12, 1993

Haloethyl-substituted steroid enzyme inhibitors

MERRELL DOW PHARMA11 citations73

US5126488AJun 30, 1992

2β,19-methyleneamino bridged steroids as aromatase inhibitors

MERRELL DOW PHARMA6 citations73

US5099037AMar 24, 1992

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase and 19-hydroxylase inhibitors

MERRELL DOW PHARMA7 citations73

US4882322ANov 21, 1989

Method of treating hyperaldosteronism using 17β-cyclopropylaminoandrostene derivatives

MERRELL DOW PHARMA0 citations51

US4954491ASep 4, 1990

Method of treatment using 18-cyanoprogesterone derivatives

MERRELL DOW PHARMA0 citations49

US4920114AApr 24, 1990

19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors

MERRELL DOW PHARMA0 citations49

US4910191AMar 20, 1990

19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors

MERRELL DOW PHARMA0 citations49

MERRELL PHARMA INC

1 patent

US6313161B1Nov 6, 2001

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase, 19-hydroxylase inhibitors and methods of their use in the treatment of estrogen mediated disorders

MERRELL PHARMA INC1 citations52

JOHNSTON J O'NEAL

MERRELL DOW PHARMA

4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase

10-Alkynyl steroids

10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase, 19-hydroxylaser inhibitors and methods of their use in the treatment of estrogen mediated disorders

Haloethyl-substituted steroid enzyme inhibitors

2β,19-methyleneamino bridged steroids as aromatase inhibitors

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase and 19-hydroxylase inhibitors

3β,17β-hydroxy-substituted steroids and related steroidal compounds

2β,19-ethylene bridged steroids as aromatase inhibitors

18-Substituted pregn-4-ene-3,20-diones

Method of treating hyperaldosteronism using 17β-cyclopropylaminoandrostene derivatives

Method of treatment using 18-cyanoprogesterone derivatives

19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors

19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors

MERRELL PHARMA INC

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase, 19-hydroxylase inhibitors and methods of their use in the treatment of estrogen mediated disorders