Inventor
BRADNER JAMES
US33 patents
⚠️ This page may combine multiple inventors who share the name “BRADNER JAMES”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
DANA FARBER CANCER INST INC
26 patentsUS10125114B2Nov 13, 2018
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC57 citations97
US9821068B2Nov 21, 2017
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC71 citations97
US9770512B2Sep 26, 2017
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC63 citations97
US9750816B2Sep 5, 2017
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC62 citations97
US9694084B2Jul 4, 2017
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC76 citations97
US10849980B2Dec 1, 2020
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC16 citations94
US10669253B2Jun 2, 2020
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC17 citations94
US10464925B2Nov 5, 2019
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC36 citations94
US10239888B2Mar 26, 2019
Targeted protein degradation using a mutant E3 ubiquitin ligase
DANA FARBER CANCER INST INC18 citations87
US10934256B2Mar 2, 2021
Compounds and methods for treating cancer
DANA FARBER CANCER INST INC4 citations83
US10464897B2Nov 5, 2019
Compounds and methods for treating cancer
DANA FARBER CANCER INST INC4 citations83
US11583586B2Feb 21, 2023
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC3 citations73
US11059801B2Jul 13, 2021
Methods to induce targeted protein degradation through bifunctional molecules
DANA FARBER CANCER INST INC2 citations73
US11845728B2Dec 19, 2023
Compounds and methods for treating cancer
DANA FARBER CANCER INST INC2 citations72
US11311609B2Apr 26, 2022
Regulating chimeric antigen receptors
DANA FARBER CANCER INST INC6 citations71
US11046954B2Jun 29, 2021
Targeted protein degradation to attenuate adoptive T-cell therapy associated adverse inflammatory responses
DANA FARBER CANCER INST INC2 citations71
US10899768B2Jan 26, 2021
Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use
DANA FARBER CANCER INST INC3 citations71
US11285218B2Mar 29, 2022
Degradation of bromodomain-containing protein 9 (BRD9) by conjugation of BRD9 inhibitors with E3 ligase ligand and methods of use
DANA FARBER CANCER INST INC5 citations68
US12441685B2Oct 14, 2025
Compounds and methods for treating cancer
DANA FARBER CANCER INST INC0 citations62
US11293023B2Apr 5, 2022
Tunable endogenous protein degradation
DANA FARBER CANCER INST INC0 citations61
US10925868B2Feb 23, 2021
Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use
DANA FARBER CANCER INST INC0 citations61
US11578075B2Feb 14, 2023
Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use
DANA FARBER CANCER INST INC1 citations60
US10702504B2Jul 7, 2020
Degradation of tripartite motif-containing protein 24 (TRIM24) by conjugation of TRIM24 inhibitors with E3 ligase ligand and methods of use
DANA FARBER CANCER INST INC1 citations56
US12129248B2Oct 29, 2024
Chromobox protein inhibitors and uses thereof
DANA FARBER CANCER INST INC0 citations55
US12023385B2Jul 2, 2024
Tunable endogenous protein degradation with heterobifunctional compounds
DANA FARBER CANCER INST INC0 citations49
US10525139B2Jan 7, 2020
Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use
DANA FARBER CANCER INST INC0 citations46
CHILDRENS MEDICAL CT CORP
3 patentsUS11944625B2Apr 2, 2024
Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies
CHILDRENS MEDICAL CT CORP1 citations71
US10980808B2Apr 20, 2021
Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies
CHILDRENS MEDICAL CT CORP4 citations71
US12569486B2Mar 10, 2026
Calmodulin inhibitors, CHK2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies
CHILDRENS MEDICAL CT CORP0 citations61