Inventor

FREIDINGER ROGER M

US60 patents

Patents

50 patents

US4820834AApr 11, 1989

Benzoxazinone and benzopyrimidinone piperidinyl tocolytic oxytocin receptor antagonists

MERCK & CO INC74 citations96

US5206234AApr 27, 1993

Benzolactam analogs as antagonists of cck

MERCK & CO INC61 citations96

US5004741AApr 2, 1991

Methods of antagonizing CCK or gastrin with benzodiazepine analogs

MERCK & CO INC59 citations96

US4310518AJan 12, 1982

Cyclic hexapeptide somatostatin analogs

MERCK & CO INC94 citations96

US4235886ANov 25, 1980

Cyclic hexapeptide somatostatin analogs

MERCK & CO INC88 citations96

US5510369AApr 23, 1996

Pyrrolidine thrombin inhibitors

MERCK & CO INC52 citations95

US5356904AOct 18, 1994

Carbostyril oxytocin receptor antagonists

MERCK & CO INC78 citations95

US5756497AMay 26, 1998

Tocolytic oxytocin receptor antagonists

MERCK & CO INC32 citations93

US5220018AJun 15, 1993

Cholecystokinin antagonists

MERCK & CO INC29 citations93

US5220017AJun 15, 1993

Cholecystokinin antagonists

MERCK & CO INC36 citations93

US5210082AMay 11, 1993

2-benzazepines with 5- and 6-membered heterocyclic rings to treat pain and anxiety disorders

MERCK & CO INC25 citations93

US5185331AFeb 9, 1993

Triazolobenzodiazepines

MERCK & CO INC23 citations93

US5177071AJan 5, 1993

1,4-benzodiazepines with 6-membered heterocyclic rings to treat panic and anxiety disorder

MERCK & CO INC47 citations93

US5175159ADec 29, 1992

3-substituted-1,4-benzodiazepines as oxytocin antagonists

MERCK & CO INC36 citations93

US5166151ANov 24, 1992

2-Benzazepines with 5- and 6-membered heterocyclic rings, compositions and medical methods of use thereof

MERCK & CO INC41 citations93

US4755508AJul 5, 1988

Benzodiazepine analogs and use as antogonists of gastrin and cholecystokinin

MERCK & CO INC49 citations93

US5834464ANov 10, 1998

Imidazolinobenzodiazepines

MERCK & CO INC29 citations92

US5439906AAug 8, 1995

Antiarrhythmic benzodiazepines

MERCK & CO INC24 citations92

US5968938AOct 19, 1999

Piperazine oxytocin receptor antagonists

MERCK & CO INC42 citations91

US5726172AMar 10, 1998

Tocolytic oxytocin receptor antagonists

MERCK & CO INC43 citations91

US4554272ANov 19, 1985

Substituted quinazolino-1,4-benzodiazepin-6,9-diones and their preparation

MERCK & CO INC20 citations82

US4535167AAug 13, 1985

Chiral, N-protected, N-substituted α-amino acids

MERCK & CO INC26 citations82

US4360516ANov 23, 1982

Modified D-retro cyclic hexapeptide somatostatin analogs

MERCK & CO INC27 citations82

US4254107AMar 3, 1981

Long-lasting agonists of enkephalin

MERCK & CO INC27 citations82

US5691332ANov 25, 1997

N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides

MERCK & CO INC15 citations74

US5378838AJan 3, 1995

Benzodiazepine cholecystokinin antagonists

MERCK & CO INC8 citations74

US5225528AJul 6, 1993

Cyclic hexapeptide oxytocin antagonists

MERCK & CO INC14 citations74

US4847248AJul 11, 1989

1,4-Benzodiazepines with 5- and 6-membered heterocyclic rings and their use as cholecystokinins and gastrin antagonists

MERCK & CO INC19 citations74

US4724237AFeb 9, 1988

2-substituted-aminomethyl-1,4-benzodiazepines

MERCK & CO INC8 citations74

US4663321AMay 5, 1987

Triazolobenzodiazepines and pharmaceutical use

MERCK & CO INC17 citations74

US4659691AApr 21, 1987

Novel cyclic Hexapeptide LHRH antagonists

MERCK & CO INC11 citations74

US4559339ADec 17, 1985

Indol-3-yl-quinazolino-1,4-benzodiazepin-5,13-diones

MERCK & CO INC7 citations74

US4493934AJan 15, 1985

2(3-Amino-2-oxopyrrolidin-1-yl) acetic acid and n-acylated derivatives thereof

MERCK & CO INC7 citations74

US4192875AMar 11, 1980

Cyclic hexapeptide

MERCK & CO INC9 citations74

US5714485AFeb 3, 1998

Piperidine and hexahydropyridazine thrombin inhibitors

MERCK & CO INC7 citations73

US5218114AJun 8, 1993

Cholecystokinin antagonists

MERCK & CO INC15 citations73

US5661163AAug 26, 1997

Alpha-1a adrenergic receptor antagonists

MERCK & CO INC12 citations72

US5204349AApr 20, 1993

Amide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists

MERCK & CO INC14 citations72

US5977115ANov 2, 1999

Alpha 1a adrenergic receptor antagonists

MERCK & CO INC10 citations71

US6090805AJul 18, 2000

Tocolytic oxytocin receptor antagonists

MERCK & CO INC7 citations69

US6544982B1Apr 8, 2003

Thrombin receptor antagonists

MERCK & CO INC5 citations63

US5691331ANov 25, 1997

N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides

MERCK & CO INC4 citations63

US5206237AApr 27, 1993

Benzodiazepine analogs

MERCK & CO INC4 citations63

US5206238AApr 27, 1993

Cholecystokinin antagonists

MERCK & CO INC3 citations63

US5089638AFeb 18, 1992

Amino acid analogs as CCK-antagonists

MERCK & CO INC5 citations63

US4735941AApr 5, 1988

1,4-benzodiazepines with 5- and 6-membered heterocyclic rings, useful as gastrointestinal and CNS agents

MERCK & CO INC6 citations63

US4563451AJan 7, 1986

Quinazolino-1,4-benzodiazepin-5,13-diones

MERCK & CO INC4 citations63

Showing the top 50 of 60 patents by PatentIndex Score.