Inventor
HOKE GLENN
US10 patents
Patents
10 patentsUS5661134AAug 26, 1997
Oligonucleotides for modulating Ha-ras or Ki-ras having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC249 citations99
US5607923AMar 4, 1997
Oligonucleotides for modulating cytomegalovirus having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC136 citations99
US5599797AFeb 4, 1997
Oligonucleotides having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC248 citations99
US5587361ADec 24, 1996
Oligonucleotides having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC1,412 citations99
US5576302ANov 19, 1996
Oligonucleotides for modulating hepatitis C virus having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC255 citations99
US5506212AApr 9, 1996
Oligonucleotides with substantially chirally pure phosphorothioate linkages
ISIS PHARMACEUTICALS INC125 citations98
US5635488AJun 3, 1997
Compounds having phosphorodithioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC92 citations96
US5620963AApr 15, 1997
Oligonucleotides for modulating protein kinase C having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC80 citations96
US6339066B1Jan 15, 2002
Antisense oligonucleotides which have phosphorothioate linkages of high chiral purity and which modulate βI, βII, γ, δ, Ε, ζ and η isoforms of human protein kinase C
ISIS PHARMACEUTICALS INC29 citations92
US5654284AAug 5, 1997
Oligonucleotides for modulating RAF kinase having phosphorothioate linkages of high chiral purity
ISIS PHARMACEUTICALS INC26 citations92