Inventor

WESS GUENTHER

DE28 patents

Patents

28 patents

US5512558AApr 30, 1996

Nor-bile acid derivatives, processes for their preparation and the use of these compounds as medicaments

HOECHST AG81 citations96

US5462933AOct 31, 1995

Modified bile acid conjugates, and their use as pharmaceuticals

HOECHST AG74 citations96

US5091386AFeb 25, 1992

7-substituted derivatives of 3,5-dihydroxyhept-6-ynoic acids and corresponding lactones and their use as hypercholeserolemics

HOECHST AG64 citations96

US4970313ANov 13, 1990

Optically active 3-demethylmevalonic acid derivatives, and intermediates

HOECHST AG59 citations95

US5250524AOct 5, 1993

Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals

HOECHST AG69 citations94

US5668126ASep 16, 1997

Bile acid derivatives, processes for their preparation, and use as pharmaceuticals

HOECHST AG28 citations92

US5646272AJul 8, 1997

Bile acid conjugates of proline hydroxylase inhibitors

HOECHST AG36 citations92

US5610151AMar 11, 1997

Monomeric bile acid derivatives, processes for their preparation and the use of these compounds as medicaments

HOECHST AG48 citations92

US5508275AApr 16, 1996

Lipid-selective antioxidants and their preparation and use

HOECHST AG39 citations92

US5466815ANov 14, 1995

Tetrazole derivatives of bile acids, and their use as lipid level lowering medicaments

HOECHST AG45 citations92

US5318987AJun 7, 1994

Lipid-selective antioxidants and their preparation and use

HOECHST AG27 citations92

US5294724AMar 15, 1994

4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters and a process for their preparation

HOECHST AG37 citations92

US5166171ANov 24, 1992

6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiphenoxymethyl-4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, and in treating hypercholesterolemia

HOECHST AG39 citations92

US4977279ADec 11, 1990

Process for the preparation of optically active 3-demethylmevalonic acid derivatives, and intermediates

HOECHST AG30 citations92

US5641767AJun 24, 1997

Modified bile acids process for their preparation and their use

HOECHST AG40 citations89

US4734406AMar 29, 1988

3-pyridylmethylnaphthyl derivatives and composition containing them useful to inhibit thromboxane synthetase

HOECHST AG8 citations73

US5559258ASep 24, 1996

Ethylenically unsaturated bile acid derivatives, processes for their preparation and precursors

HOECHST AG3 citations63

US5486626AJan 23, 1996

Process for the preparation of 3β-aminocholanic acid derivatives

HOECHST AG3 citations63

US5428182AJun 27, 1995

Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals

HOECHST AG2 citations63

US5204351AApr 20, 1993

6-fluoro-3,5-dihydroxy carboxylic acids and derivatives thereof

HOECHST AG3 citations63

US4855323AAug 8, 1989

Leukotriene antagonists, a process for the preparation thereof, and the use thereof for the treatment of diseases

HOECHST AG2 citations62

US4778817AOct 18, 1988

3-Demethylmevalonic acid derivatives, a process for their preparation pharmaceutical products based on these compounds, their use and intermediates

HOECHST AG2 citations61

US4946852AAug 7, 1990

4(R)-substituted 6(S)-phenoxymethyl-, 6(S)-β-phenylethyl- and 6(S)-β-styryl-tetrahydropyran-2-ones, a highly stereoselective process for their preparation, pharmaceutical products based on these compounds, and their use

HOECHST AG0 citations40

US4610999ASep 9, 1986

4-substituted Δ2-imidazolinyl-thioethers with prostaglandin-like activity

HOECHST AG0 citations37

US4611000ASep 9, 1986

5-substituted Δ2-imidazolinyl-thioethers with prostaglandin-like activity

HOECHST AG0 citations37

WESS GUENTHER

Patents

Nor-bile acid derivatives, processes for their preparation and the use of these compounds as medicaments

Modified bile acid conjugates, and their use as pharmaceuticals

7-substituted derivatives of 3,5-dihydroxyhept-6-ynoic acids and corresponding lactones and their use as hypercholeserolemics

Optically active 3-demethylmevalonic acid derivatives, and intermediates

Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals

Bile acid derivatives, processes for their preparation, and use as pharmaceuticals

Bile acid conjugates of proline hydroxylase inhibitors

Monomeric bile acid derivatives, processes for their preparation and the use of these compounds as medicaments

Lipid-selective antioxidants and their preparation and use

Tetrazole derivatives of bile acids, and their use as lipid level lowering medicaments

Lipid-selective antioxidants and their preparation and use

4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters and a process for their preparation

6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiphenoxymethyl-4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, and in treating hypercholesterolemia

Process for the preparation of optically active 3-demethylmevalonic acid derivatives, and intermediates

Modified bile acids process for their preparation and their use

3-pyridylmethylnaphthyl derivatives and composition containing them useful to inhibit thromboxane synthetase

Ethylenically unsaturated bile acid derivatives, processes for their preparation and precursors

Process for the preparation of 3β-aminocholanic acid derivatives

Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals

6-fluoro-3,5-dihydroxy carboxylic acids and derivatives thereof

Leukotriene antagonists, a process for the preparation thereof, and the use thereof for the treatment of diseases

Naphthyl imidazolyl compounds and pharmaceutical compositions

3-pyridyl compounds and use as thromboxane synthetase inhibitors

Imidazolyl compounds and their use as medicaments

3-Demethylmevalonic acid derivatives, a process for their preparation pharmaceutical products based on these compounds, their use and intermediates

4(R)-substituted 6(S)-phenoxymethyl-, 6(S)-β-phenylethyl- and 6(S)-β-styryl-tetrahydropyran-2-ones, a highly stereoselective process for their preparation, pharmaceutical products based on these compounds, and their use

4-substituted Δ2-imidazolinyl-thioethers with prostaglandin-like activity

5-substituted Δ2-imidazolinyl-thioethers with prostaglandin-like activity