Inventor
RUEHER DANIEL
FR34 patents
⚠️ This page may combine multiple inventors who share the name “RUEHER DANIEL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
HOFFMANN LA ROCHE
27 patentsUS12209091B2Jan 28, 2025
Isoindolinone derivatives as selective allosteric inhibitors of Egfr mutant cancers
HOFFMANN LA ROCHE7 citations85
US8618296B2Dec 31, 2013
Arylethynyl derivatives
HOFFMANN LA ROCHE4 citations74
US8513273B2Aug 20, 2013
Arylethynyl derivatives
HOFFMANN LA ROCHE4 citations74
US9695128B2Jul 4, 2017
Ethynyl derivatives
HOFFMANN LA ROCHE4 citations73
US9682959B2Jun 20, 2017
Ethynyl derivatives
HOFFMANN LA ROCHE2 citations73
US8969338B2Mar 3, 2015
Ethynyl derivatives
HOFFMANN LA ROCHE4 citations73
US8716316B2May 6, 2014
Positive allosteric modulators (PAM)
HOFFMANN LA ROCHE4 citations73
US12344613B2Jul 1, 2025
EGFR inhibitor for the treatment of cancer
HOFFMANN LA ROCHE3 citations72
US11708354B2Jul 25, 2023
2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds
HOFFMANN LA ROCHE3 citations72
US11117890B2Sep 14, 2021
Substituted isoindole allosteric EGFR inhibitors
HOFFMANN LA ROCHE3 citations72
US10882848B2Jan 5, 2021
2-benzopyrazinyl-n-heteroaryl-2-phenyl-acetamide compounds
HOFFMANN LA ROCHE3 citations72
US10189848B2Jan 29, 2019
Ethynyl derivatives
HOFFMANN LA ROCHE4 citations72
US10065956B2Sep 4, 2018
Ethynyl derivatives
HOFFMANN LA ROCHE4 citations72
US9725416B2Aug 8, 2017
Ethynyl derivatives
HOFFMANN LA ROCHE4 citations72
US9359301B2Jun 7, 2016
Ethynyl derivatives
HOFFMANN LA ROCHE2 citations63
US9315498B2Apr 19, 2016
Arlethynyl derivatives
HOFFMANN LA ROCHE2 citations63
US12145940B2Nov 19, 2024
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations62
US12006323B2Jun 11, 2024
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations62
US11242349B2Feb 8, 2022
Ethynyl derivatives
HOFFMANN LA ROCHE1 citations62
US11034699B2Jun 15, 2021
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations62
US12479849B2Nov 25, 2025
EGFR inhibitors for the treatment of cancer
HOFFMANN LA ROCHE0 citations60
US9751856B2Sep 5, 2017
Ethynyl derivatives
HOFFMANN LA ROCHE1 citations52
US9328070B2May 3, 2016
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations52
US9227959B2Jan 5, 2016
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations52
US8530472B2Sep 10, 2013
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations42
US10011607B2Jul 3, 2018
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations41
US9676732B2Jun 13, 2017
Ethynyl derivatives
HOFFMANN LA ROCHE0 citations41
C4 THERAPEUTICS INC
3 patentsUS12371442B2Jul 29, 2025
Isoindolinone and indazole compounds for the degradation of EGFR
C4 THERAPEUTICS INC1 citations74
US11673902B2Jun 13, 2023
Isoindolinone and indazole compounds for the degradation of EGFR
C4 THERAPEUTICS INC3 citations72
US12486290B2Dec 2, 2025
Isoindolinone and indazole compounds for the degradation of EGFR
C4 THERAPEUTICS INC0 citations62