Inventor
CAPALDI DANIEL C
US23 patents
Patents
23 patentsUS7041816B2May 9, 2006
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC240 citations98
US6858715B2Feb 22, 2005
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC214 citations98
US6020475AFeb 1, 2000
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC99 citations98
US6465628B1Oct 15, 2002
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC82 citations97
US5760209AJun 2, 1998
Protecting group for synthesizing oligonucleotide analogs
ISIS PHARMACEUTICALS INC72 citations96
US7427675B2Sep 23, 2008
Compounds and methods for the characterization of oligonucleotides
ISIS PHARMACEUTICALS INC113 citations92
US6649750B1Nov 18, 2003
Process for the preparation of oligonucleotide compounds
ISIS PHARMACEUTICALS INC26 citations92
US5959099ASep 28, 1999
Protecting group for synthesizing oligonucleotide analogs
ISIS PHARMACEUTICALS INC21 citations92
US5902881AMay 11, 1999
Reagent useful for synthesizing sulfurized oligonucleotide analogs
ISIS PHARMACEUTICALS INC14 citations82
US5783690AJul 21, 1998
Protecting group for synthesizing oligonucleotide analogs
ISIS PHARMACEUTICALS INC16 citations82
US6335439B1Jan 1, 2002
Method of preparing phosphoramidites
ISIS PHARMACEUTICALS INC19 citations79
US6610842B1Aug 26, 2003
Processes for the synthesis of oligomers using phosphoramidite compositions
ISIS PHARMACEUTICALS INC9 citations74
US6160152ADec 12, 2000
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC9 citations74
US7199236B2Apr 3, 2007
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC8 citations73
US7173123B2Feb 6, 2007
Methods for detection of chloral hydrate in dichloroacetic acid
ISIS PHARMACEUTICALS INC4 citations71
US6645716B2Nov 11, 2003
Methods for detection of chloral hydrate in dichloroacetic acid
ISIS PHARMACEUTICALS INC8 citations71
US7186822B2Mar 6, 2007
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC2 citations63
US6040438AMar 21, 2000
Reagent useful for synthesizing sulfurized oligonucleotide analogs
ISIS PHARMACEUTICALS INC2 citations63
US7227016B2Jun 5, 2007
Process for the synthesis of oligomeric compounds
ISIS PHARMACEUTICALS INC1 citations62
US7446193B2Nov 4, 2008
Methods for detection of chloral hydrate in dichloroacetic acid
ISIS PHARMACEUTICALS INC2 citations60
US6858722B2Feb 22, 2005
Oligomer phosphoramidite compositions and processes for synthesizing the same
ISIS PHARMACEUTICALS INC1 citations52
US6399831B1Jun 4, 2002
Reagent useful for synthesizing sulfurized oligonucleotide analogs
ISIS PHARMACEUTICALS INC0 citations52
US7759480B2Jul 20, 2010
Chloral-free DCA in oligonucleotide synthesis
ISIS PHARMACEUTICALS INC0 citations48