Inventor
KOSTER WILLIAM H
US25 patents
Patents
25 patentsUS4576749AMar 18, 1986
3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones
SQUIBB & SONS INC71 citations96
US4775670AOct 4, 1988
2-oxo-1-azetidinesulfonic acid salts
SQUIBB & SONS INC61 citations95
US4743685AMay 10, 1988
2-oxo-1-[[(substituted sulfonyl)amino]carbonyl]azetidines
SQUIBB & SONS INC28 citations92
US4237128ADec 2, 1980
7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides
SQUIBB & SONS INC19 citations82
US4529698AJul 16, 1985
Process for preparing a 2-oxo-1-azetidinesulfonic acid salt
SQUIBB & SONS INC20 citations81
US5290929AMar 1, 1994
Heteroaryl derivatives of monocyclic beta-lactam antibiotics
SQUIBB & SONS INC17 citations78
US4680388AJul 14, 1987
O-sulfated spiro β-lactam hydroxamic acids
SQUIBB & SONS INC10 citations74
US4638061AJan 20, 1987
[3S(Z)]-2-[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy] acetic acid and intermediate
SQUIBB & SONS INC8 citations74
US4638060AJan 20, 1987
O-sulfated spiro β-lactam hydroxamic acids
SQUIBB & SONS INC9 citations74
US4478749AOct 23, 1984
2-Oxo-1-(substituted phosphorous)azetidines
SQUIBB & SONS INC9 citations74
US4203992AMay 20, 1980
β-Bromopenicillanic acid sulfone
SQUIBB & SONS INC11 citations74
US4062842ADec 13, 1977
Method for preparing 7-substituted cephalosporins and 6-substituted penicillins by replacement of sulfur-containing groups
SQUIBB & SONS INC7 citations74
US4751220AJun 14, 1988
Crystalline salts of [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy]acetic acid
SQUIBB & SONS INC12 citations68
US4654426AMar 31, 1987
Acetylenic antibiotics
SQUIBB & SONS INC2 citations63
US4723002AFeb 2, 1988
1-(substituted phosphorous)-azetidinone antibacterials
SQUIBB & SONS INC2 citations62
US4681937AJul 21, 1987
3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids, phosphoric acid and phosphoric acid esters
SQUIBB & SONS INC3 citations62
US4548751AOct 22, 1985
(2-Oxo-1-azetidinyloxy)-2-propenoic acid
SQUIBB & SONS INC2 citations62
US5705645AJan 6, 1998
Hereroaryl derivatives of monocyclic beta-lactam antibiotics
SQUIBB & SONS INC1 citations61
US4443374AApr 17, 1984
Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives
SQUIBB & SONS INC3 citations61
US4574153AMar 4, 1986
8-Oxo-2-oxa-1-azabicyclo(4.2.0)octane-3-carboxylic acids
SQUIBB & SONS INC4 citations60
US4670554AJun 2, 1987
((3-Acylamino-2-oxo-1-azetidinyl)oxy)methyl)phosphinic acids
SQUIBB & SONS INC1 citations52
US4588828AMay 13, 1986
Acetylenic antibiotics
SQUIBB & SONS INC1 citations52
US4587051AMay 6, 1986
Desulfonation process for preparing 2-azetidinones
SQUIBB & SONS INC1 citations52
US4129731ADec 12, 1978
Process for converting 3-methylene cephalosporins to 3-heterothiomethyl cephalosporins
SQUIBB & SONS INC1 citations52
US5420277AMay 30, 1995
Intermediates for the preparation of heteroaryl derivatives of monocyclic beta-lactam antiobiotics
SQUIBB & SONS INC0 citations48