P

Inventor

COLE DOUGLAS L

US186 patents
⚠️ This page may combine multiple inventors who share the name “COLE DOUGLAS L”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

ISIS PHARMACEUTICALS INC

27 patents
US6294664B1Sep 25, 2001

Synthesis of oligonucleotides

ISIS PHARMACEUTICALS INC228 citations99
US5571902ANov 5, 1996

Synthesis of oligonucleotides

ISIS PHARMACEUTICALS INC228 citations99
US7041816B2May 9, 2006

Process for the synthesis of oligomeric compounds

ISIS PHARMACEUTICALS INC240 citations98
US6858715B2Feb 22, 2005

Process for the synthesis of oligomeric compounds

ISIS PHARMACEUTICALS INC214 citations98
US5614621AMar 25, 1997

Process for preparing oligonucleotides using silyl-containing diamino phosphorous reagents

ISIS PHARMACEUTICALS INC116 citations98
US6465628B1Oct 15, 2002

Process for the synthesis of oligomeric compounds

ISIS PHARMACEUTICALS INC82 citations97
US6242591B1Jun 5, 2001

Synthesis of sulfurized 2'-substituted oligonucleotides

ISIS PHARMACEUTICALS INC45 citations96
US5760209AJun 2, 1998

Protecting group for synthesizing oligonucleotide analogs

ISIS PHARMACEUTICALS INC72 citations96
US5510476AApr 23, 1996

Carbocation scavenging during oligonucleotide synthesis

ISIS PHARMACEUTICALS INC63 citations95
US6001982ADec 14, 1999

Synthesis of oligonucleotides

ISIS PHARMACEUTICALS INC26 citations93
US6649750B1Nov 18, 2003

Process for the preparation of oligonucleotide compounds

ISIS PHARMACEUTICALS INC26 citations92
US6326478B1Dec 4, 2001

Process for the synthesis of oligomeric compounds

ISIS PHARMACEUTICALS INC33 citations92
US6114519ASep 5, 2000

Synthesis of sulfurized oligonucleotides

ISIS PHARMACEUTICALS INC40 citations92
US5959099ASep 28, 1999

Protecting group for synthesizing oligonucleotide analogs

ISIS PHARMACEUTICALS INC21 citations92
US5714597AFeb 3, 1998

Use of carbocation scavenger during oligonucleotide synthesis

ISIS PHARMACEUTICALS INC23 citations91
US7227015B2Jun 5, 2007

Synthesis of sulfurized oligonucleotides

ISIS PHARMACEUTICALS INC11 citations84
US5902881AMay 11, 1999

Reagent useful for synthesizing sulfurized oligonucleotide analogs

ISIS PHARMACEUTICALS INC14 citations82
US5847106ADec 8, 1998

Monomeric and dimeric nucleosides with silyl-containing diamino phosphorous linkages

ISIS PHARMACEUTICALS INC14 citations82
US5783690AJul 21, 1998

Protecting group for synthesizing oligonucleotide analogs

ISIS PHARMACEUTICALS INC16 citations82
US7378516B2May 27, 2008

Synthesis of sulfurized oligonucleotides

ISIS PHARMACEUTICALS INC8 citations74
US6677471B2Jan 13, 2004

Intermediates for the synthesis of oligonucleotide analogues

ISIS PHARMACEUTICALS INC4 citations74
US6610842B1Aug 26, 2003

Processes for the synthesis of oligomers using phosphoramidite compositions

ISIS PHARMACEUTICALS INC9 citations74
US6521775B2Feb 18, 2003

Process for the synthesis of oligomeric compounds

ISIS PHARMACEUTICALS INC4 citations74
US6403781B2Jun 11, 2002

Method of synthesizing phosphorothioate oligonucleotides

ISIS PHARMACEUTICALS INC11 citations74
US6399756B1Jun 4, 2002

Process for the synthesis of oligomeric compounds

ISIS PHARMACEUTICALS INC6 citations74
US6211350B1Apr 3, 2001

Synthesis of oligonucleotides

ISIS PHARMACEUTICALS INC4 citations74
US5955600ASep 21, 1999

Method for the synthesis of nucleotide or oligonucleotide phosphoramidites

ISIS PHARMACEUTICALS INC12 citations74

MIKRON IND

9 patents

MIKRON IND INC

9 patents

MARION MERRELL DOW INC

2 patents

HOECHST MARION ROUSSEL INC

1 patent

MERCK & CO INC

1 patent

COLE DOUGLAS L

1 patent

Showing the top 50 of 186 patents by PatentIndex Score.