Inventor
HELDIN CARL-HENRIK
SE42 patents
⚠️ This page may combine multiple inventors who share the name “HELDIN CARL-HENRIK”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
LUDWIG INST CANCER RES
26 patentsUS5280109AJan 18, 1994
Isolated, large latent complexes of TGF-β2 and TGF-β3, and new binding protein for latent form TGF-β1, TGF-β2 and TGF-β3 LTBP-2
LUDWIG INST CANCER RES44 citations95
US5229495AJul 20, 1993
Substantially pure receptor like TGF-β 1 binding molecules and uses thereof
LUDWIG INST CANCER RES64 citations94
US5326695AJul 5, 1994
Platelet derived growth factor agonists
LUDWIG INST CANCER RES96 citations93
US6316217B1Nov 13, 2001
Activin receptor-like kinases, proteins having serine threonine kinase domains and polynucleotides encoding same
LUDWIG INST CANCER RES21 citations92
US6207814B1Mar 27, 2001
Activin receptor-like kinases, ALK-3 and ALK-6, and nucleic acids encoding them
LUDWIG INST CANCER RES15 citations92
US5346993ASep 13, 1994
Isolated, large latent complexes of TGF-β2 and TGF-β3, and new binding protein for latent form TGF-β1, TGF-β2 and TGF-β3 LTBP-2
LUDWIG INST CANCER RES30 citations92
US6605443B1Aug 12, 2003
Method for identifying compounds that affect Smad7 binding
LUDWIG INST CANCER RES35 citations91
US6251628B1Jun 26, 2001
Isolated nucleic acid molecules encoding Smad7
LUDWIG INST CANCER RES31 citations91
US5731200AMar 24, 1998
Isolated nucleic acid encoding receptor-like TGF-β1 binding protein
LUDWIG INST CANCER RES18 citations91
US6706687B1Mar 16, 2004
Platelet-derived growth factor D
LUDWIG INST CANCER RES41 citations89
US6331621B1Dec 18, 2001
Isolated nucleic acid molecules which encode activin-receptor like kinases, expression vectors and cells containing these
LUDWIG INST CANCER RES10 citations81
US5227302AJul 13, 1993
DNA encoding platelet derived endothelial cell growth factor (PD-ECGF)
LUDWIG INST CANCER RES18 citations79
US7592428B1Sep 22, 2009
Antibodies which bind specifically to activin receptor like kinases
LUDWIG INST CANCER RES7 citations73
US6982319B2Jan 3, 2006
Antibodies which bind specifically to activin receptor-like kinases
LUDWIG INST CANCER RES6 citations73
US6271365B1Aug 7, 2001
Activin like receptor--Isolated kinase proteins ALK-2, ALK-4, ALK-5, and nucleic acid molecules encoding them
LUDWIG INST CANCER RES7 citations73
US5756686AMay 26, 1998
Peptides derived from endothelial cell growth factor
LUDWIG INST CANCER RES11 citations72
US6103869AAug 15, 2000
Smad2 phosphorylation and interaction with Smad4
LUDWIG INST CANCER RES11 citations70
US5444151AAug 22, 1995
Platelet derived growth factor antagonists
LUDWIG INST CANCER RES9 citations69
US5177197AJan 5, 1993
Isolated nucleotide sequence expressing human transforming growth factor-β1-binding protein
LUDWIG INST CANCER RES10 citations69
US5821075AOct 13, 1998
Nucleotide sequences for novel protein tyrosine phosphatases
LUDWIG INST CANCER RES11 citations67
US6673570B1Jan 6, 2004
Smad associating polypeptides
LUDWIG INST CANCER RES3 citations58
US6066472AMay 23, 2000
Nucleic acids coding for GLM-2, a novel protein tyrosine phosphatase
LUDWIG INST CANCER RES3 citations58
US7932351B2Apr 26, 2011
Activin receptor-like kinase-1 proteins having serine-threonine kinase domains
LUDWIG INST CANCER RES0 citations51
US6368829B1Apr 9, 2002
Smad2 phosphorylation and interaction with Smad4
LUDWIG INST CANCER RES1 citations48
US6475775B1Nov 5, 2002
PARG, a GTPase activating protein which interacts with PTPL1
LUDWIG INST CANCER RES0 citations47
US6083721AJul 4, 2000
Isolated nucleic acid molecules encoding PARG, a GTPase activating protein which interacts with PTPL1
LUDWIG INST CANCER RES0 citations47
CHIRON CORP
3 patentsUS5219759AJun 15, 1993
Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors
CHIRON CORP47 citations94
US5605816AFeb 25, 1997
Recombinant DNA encoding PDGF A-chain polypeptides
CHIRON CORP1 citations61
US6939849B1Sep 6, 2005
Recombinant PDGF A-chain homodimers and methods of use
CHIRON CORP0 citations50