Inventor
LOSCALZO JOSEPH
US33 patents
⚠️ This page may combine multiple inventors who share the name “LOSCALZO JOSEPH”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
BRIGHAM & WOMENS HOSPITAL
21 patentsUS5385937AJan 31, 1995
Nitrosation of homocysteine as a method for treating homocysteinemia
BRIGHAM & WOMENS HOSPITAL156 citations99
US6471978B1Oct 29, 2002
Localized use of nitric oxide-adducts to prevent internal tissue damage
BRIGHAM & WOMENS HOSPITAL89 citations98
US6255277B1Jul 3, 2001
Localized use of nitric oxide-adducts to prevent internal tissue damage
BRIGHAM & WOMENS HOSPITAL83 citations97
US5380758AJan 10, 1995
S-nitrosothiols as smooth muscle relaxants and therapeutic uses thereof
BRIGHAM & WOMENS HOSPITAL255 citations97
US5025001AJun 18, 1991
S-nitroso derivatives of ACE inhibitors and the use thereof
BRIGHAM & WOMENS HOSPITAL89 citations96
US5002964AMar 26, 1991
S-nitrosocaptopril compounds and the use thereof
BRIGHAM & WOMENS HOSPITAL71 citations96
US6174539B1Jan 16, 2001
Localized use of nitric oxide adducts to prevent internal tissue damage
BRIGHAM & WOMENS HOSPITAL68 citations95
US5863890AJan 26, 1999
Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality
BRIGHAM & WOMENS HOSPITAL35 citations95
US5648393AJul 15, 1997
Treatment of male impotence with s-nitrosylated compounds
BRIGHAM & WOMENS HOSPITAL66 citations95
US5593876AJan 14, 1997
Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality
BRIGHAM & WOMENS HOSPITAL74 citations95
US6291424B1Sep 18, 2001
Nitrosated and nitrosylated heme proteins
BRIGHAM & WOMENS HOSPITAL51 citations93
US5427797AJun 27, 1995
Systemic effects of nitric oxide inhalation
BRIGHAM & WOMENS HOSPITAL158 citations93
US7157500B2Jan 2, 2007
Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality
BRIGHAM & WOMENS HOSPITAL17 citations92
US7033999B2Apr 25, 2006
Nitrosated and nitrosylated heme proteins
BRIGHAM & WOMENS HOSPITAL24 citations92
US6562344B1May 13, 2003
Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality
BRIGHAM & WOMENS HOSPITAL14 citations92
US5536723AJul 16, 1996
S-nitroso derivatives of hydrazinoacetic acids, 1-[(acylthio and (mercapto)-1-oxoalkyl]-1,2,34-Tetrahydroquinoline-2-carboxylic acids and alanyl prolines and isoquinolines
BRIGHAM & WOMENS HOSPITAL42 citations92
US5459076AOct 17, 1995
Method for detecting nitric oxide, nitrosonium equivalents, S-nitrosothiols and S-nitroso-proteins in biological systems
BRIGHAM & WOMENS HOSPITAL31 citations92
US5356890AOct 18, 1994
S-nitroso derivatives of ace inhibitors and the use thereof
BRIGHAM & WOMENS HOSPITAL24 citations92
US5298506AMar 29, 1994
Use of guanylate cyclase inhibitors in the treatment of shock
BRIGHAM & WOMENS HOSPITAL40 citations92
US5187183AFeb 16, 1993
S-nitroso derivatives of ACE inhibitors and the use thereof
BRIGHAM & WOMENS HOSPITAL31 citations92
US6583113B2Jun 24, 2003
Nitrosated and nitrosylated heme proteins
BRIGHAM & WOMENS HOSPITAL31 citations89
NITROMED INC
6 patentsUS6087479AJul 11, 2000
Localized use of nitric oxide-adducts to prevent internal tissue damage
NITROMED INC201 citations98
US6352709B1Mar 5, 2002
Localized use of nitric oxide-adducts to prevent internal tissue damage
NITROMED INC31 citations95
US7537785B2May 26, 2009
Composition for treating vascular diseases characterized by nitric oxide insufficiency
NITROMED INC44 citations91
US7235237B2Jun 26, 2007
Methods of treating vascular diseases characterized by nitric oxide insufficiency
NITROMED INC37 citations91
US7708989B2May 4, 2010
Methods of treating vascular diseases characterized by nitric oxide insufficiency
NITROMED INC4 citations61
US7556824B2Jul 7, 2009
Transdermal patch composition for treating vascular diseases characterized by nitric oxide insufficiency
NITROMED INC0 citations50
UNIV BOSTON
3 patentsUS6635273B1Oct 21, 2003
Methods of treating vascular diseases characterized by nitric oxide insufficiency
UNIV BOSTON102 citations96
US6589759B1Jul 8, 2003
Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
UNIV BOSTON31 citations86
US6489290B2Dec 3, 2002
Antiplatelet agent
UNIV BOSTON4 citations57