Inventor
CLARKE MICHAEL F
US33 patents
⚠️ This page may combine multiple inventors who share the name “CLARKE MICHAEL F”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
UNIV MICHIGAN
22 patentsUS6326198B1Dec 4, 2001
Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
UNIV MICHIGAN220 citations99
US5670147ASep 23, 1997
Compositions containing cultured mitotic human stem cells
UNIV MICHIGAN126 citations99
US5670351ASep 23, 1997
Methods and compositions for the ex vivo replication of human hematopoietic stem cells
UNIV MICHIGAN155 citations99
US5646043AJul 8, 1997
Methods for the ex vivo replication of human stem cells and/or expansion of human progenitor cells
UNIV MICHIGAN204 citations99
US5635386AJun 3, 1997
Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture
UNIV MICHIGAN220 citations99
US5605822AFeb 25, 1997
Methods, compositions and devices for growing human hematopoietic cells
UNIV MICHIGAN187 citations99
US5437994AAug 1, 1995
Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
UNIV MICHIGAN297 citations99
US5399493AMar 21, 1995
Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
UNIV MICHIGAN150 citations99
US7115360B2Oct 3, 2006
Isolation and use of solid tumor stem cells
UNIV MICHIGAN95 citations98
US6984522B2Jan 10, 2006
Isolation and use of solid tumor stem cells
UNIV MICHIGAN132 citations98
US6667034B2Dec 23, 2003
Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture, methods for assaying the effect of substances on lineage-specific cell production, and cell compositions produced by these cultures
UNIV MICHIGAN97 citations98
US7754206B2Jul 13, 2010
Method for treating cancer using a Notch4 ligand antagonist
UNIV MICHIGAN59 citations97
US7850961B2Dec 14, 2010
Methods for targeting solid tumor stem cells in a solid tumor using a notch4 receptor antagonist
UNIV MICHIGAN28 citations95
US5534423AJul 9, 1996
Methods of increasing rates of infection by directing motion of vectors
UNIV MICHIGAN57 citations94
US7939263B2May 10, 2011
Compositions and methods for treating and diagnosing cancer
UNIV MICHIGAN38 citations92
US7713710B2May 11, 2010
Isolation and use of solid tumor stem cells
UNIV MICHIGAN23 citations92
US5866400AFeb 2, 1999
Methods of increasing rates of infection by directing motion of vectors
UNIV MICHIGAN71 citations92
US7723112B2May 25, 2010
Compositions and methods for treating and diagnosing cancer
UNIV MICHIGAN27 citations89
US8044259B2Oct 25, 2011
Determining the capability of a test compound to affect solid tumor stem cells
UNIV MICHIGAN4 citations63
US9089556B2Jul 28, 2015
Method for treating cancer using an antibody that inhibits notch4 signaling
UNIV MICHIGAN1 citations62
US5672494ASep 30, 1997
Methods of increasing rates of infection by directing motion of vectors
UNIV MICHIGAN1 citations60
US8357491B2Jan 22, 2013
Isolation and use of solid tumor stem cells
UNIV MICHIGAN0 citations51
CLARKE MICHAEL F
4 patentsUS9329170B2May 3, 2016
Single cell gene expression for diagnosis, prognosis and identification of drug targets
CLARKE MICHAEL F75 citations94
US9850483B2Dec 26, 2017
Methods and systems for analysis of single cells
CLARKE MICHAEL F63 citations93
US8420885B2Apr 16, 2013
Determining the capability of a test compound to affect solid tumor stem cells
CLARKE MICHAEL F5 citations72
US9492538B2Nov 15, 2016
Isolation and use of solid tumor stem cells
CLARKE MICHAEL F0 citations51