P

Inventor

DEAN NICHOLAS M

US50 patents
⚠️ This page may combine multiple inventors who share the name “DEAN NICHOLAS M”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

ISIS PHARMACEUTICALS INC

38 patents
US6001992ADec 14, 1999

Antisense modulation of novel anti-apoptotic bcl-2-related proteins

ISIS PHARMACEUTICALS INC230 citations99
US5877309AMar 2, 1999

Antisense oligonucleotides against JNK

ISIS PHARMACEUTICALS INC189 citations99
US6172216B1Jan 9, 2001

Antisense modulation of BCL-X expression

ISIS PHARMACEUTICALS INC399 citations98
US6214986B1Apr 10, 2001

Antisense modulation of bcl-x expression

ISIS PHARMACEUTICALS INC86 citations97
US5801154ASep 1, 1998

Antisense oligonucleotide modulation of multidrug resistance-associated protein

ISIS PHARMACEUTICALS INC1,636 citations97
US7148204B2Dec 12, 2006

Antisense modulation of bcl-x expression

ISIS PHARMACEUTICALS INC145 citations96
US6136603AOct 24, 2000

Antisense modulation of interleukin-5 signal transduction

ISIS PHARMACEUTICALS INC72 citations96
US5985558ANov 16, 1999

Antisense oligonucleotide compositions and methods for the inibition of c-Jun and c-Fos

ISIS PHARMACEUTICALS INC101 citations96
US7879992B2Feb 1, 2011

Modification of MyD88 splicing using modified oligonucleotides

ISIS PHARMACEUTICALS INC42 citations95
US6312900B1Nov 6, 2001

Antisense oligonucleotide compositions and methods for the modulation of activating protein 1

ISIS PHARMACEUTICALS INC59 citations94
US6346416B1Feb 12, 2002

Antisense inhibition of HPK/GCK-like kinase expression

ISIS PHARMACEUTICALS INC19 citations93
US6087489AJul 11, 2000

Antisense oligonucleotide modulation of human thymidylate synthase expression

ISIS PHARMACEUTICALS INC18 citations93
US6001991ADec 14, 1999

Antisense oligonucleotide modulation of MDR P-glycoprotein gene expression

ISIS PHARMACEUTICALS INC35 citations93
US6809193B2Oct 26, 2004

Antisense oligonucleotide compositions and methods for the modulation of JNK proteins

ISIS PHARMACEUTICALS INC33 citations92
US6339066B1Jan 15, 2002

Antisense oligonucleotides which have phosphorothioate linkages of high chiral purity and which modulate βI, βII, γ, δ, Ε, ζ and η isoforms of human protein kinase C

ISIS PHARMACEUTICALS INC29 citations92
US6204055B1Mar 20, 2001

Antisense inhibition of Fas mediated signaling

ISIS PHARMACEUTICALS INC31 citations92
US5959096ASep 28, 1999

Antisense oligonucleotides against human protein kinase C

ISIS PHARMACEUTICALS INC20 citations92
US5916807AJun 29, 1999

Antisense oligonucleotides against human protein kinase C

ISIS PHARMACEUTICALS INC25 citations92
US5885970AMar 23, 1999

Antisense oligonucleotides against human protein kinase C

ISIS PHARMACEUTICALS INC48 citations92
US5703054ADec 30, 1997

Oligonucleotide modulation of protein kinase C

ISIS PHARMACEUTICALS INC41 citations92
US7759318B1Jul 20, 2010

Identification of novel pathways, genes and promoter motifs regulating adipogenesis

ISIS PHARMACEUTICALS INC23 citations91
US6436909B1Aug 20, 2002

Antisense inhibition of transforming growth factor-β expression

ISIS PHARMACEUTICALS INC21 citations91
US5681747AOct 28, 1997

Nucleic acid sequences encoding protein kinase C and antisense inhibition of expression thereof

ISIS PHARMACEUTICALS INC37 citations91
US9157081B2Oct 13, 2015

Chimeric oligomeric compounds for modulation of splicing

ISIS PHARMACEUTICALS INC29 citations90
US6537973B1Mar 25, 2003

Oligonucleotide inhibition of protein kinase C

ISIS PHARMACEUTICALS INC24 citations86
US6180353B1Jan 30, 2001

Antisense modulation of daxx expression

ISIS PHARMACEUTICALS INC16 citations84
US6235723B1May 22, 2001

Antisense oligonucleotide modulation of human protein kinase C-δ expression

ISIS PHARMACEUTICALS INC9 citations74
US5948898ASep 7, 1999

Methoxyethoxy oligonucleotides for modulation of protein kinase C expression

ISIS PHARMACEUTICALS INC9 citations74
US6117847ASep 12, 2000

Oligonucleotides for enhanced modulation of protein kinase C expression

ISIS PHARMACEUTICALS INC9 citations73
US5922686AJul 13, 1999

Oligonucleotide modulation of protein kinase C

ISIS PHARMACEUTICALS INC8 citations73
US5882927AMar 16, 1999

Oligonucleotide inhibition of protein kinase C

ISIS PHARMACEUTICALS INC15 citations73
US6015892AJan 18, 2000

Oligonucleotide modulation of protein kinase C

ISIS PHARMACEUTICALS INC6 citations72
US6653133B1Nov 25, 2003

Antisense modulation of Fas mediated signaling

ISIS PHARMACEUTICALS INC2 citations63
US6300320B1Oct 9, 2001

Modulation of c-jun using inhibitors of protein kinase C

ISIS PHARMACEUTICALS INC3 citations63
US6153599ANov 28, 2000

Methoxyethoxy oligonucleotides for modulation of protein kinase C expression

ISIS PHARMACEUTICALS INC4 citations63
US7563885B1Jul 21, 2009

Modulation of Tudor-SN expression

ISIS PHARMACEUTICALS INC2 citations60
US7375212B2May 20, 2008

Modulation of Aurora B expression

ISIS PHARMACEUTICALS INC1 citations52
US6599742B2Jul 29, 2003

Antisense oligonucleotide inhibition of human serine/threonine protein phosphatase gene expression

ISIS PHARMACEUTICALS INC0 citations50

DEAN NICHOLAS M

4 patents

BENNETT C FRANK

1 patent

UNIV SOUTH ALABAMA

1 patent

NOVARTIS AG

1 patent

ANTISENSE THERAPEUTICS LTD

1 patent

VICKERS TIMOTHY

1 patent

DOBIE KENNETH W

1 patent

EXCALIARD PHARMACEUTICALS INC

1 patent

MUSTOE THOMAS A

1 patent