Inventor
BARTA THOMAS E
US41 patents
⚠️ This page may combine multiple inventors who share the name “BARTA THOMAS E”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SRX CARDIO LLC
15 patentsUS10980801B2Apr 20, 2021
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
SRX CARDIO LLC6 citations83
US10865185B2Dec 15, 2020
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity
SRX CARDIO LLC5 citations83
US10568882B2Feb 25, 2020
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
SRX CARDIO LLC6 citations83
US10688114B2Jun 23, 2020
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity
SRX CARDIO LLC5 citations82
US10307433B2Jun 4, 2019
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity
SRX CARDIO LLC5 citations82
US10034892B2Jul 31, 2018
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity
SRX CARDIO LLC5 citations82
US10287317B2May 14, 2019
Proprotein convertase subtilisin kexin type 9 (PCSK9) allosteric binding ligands to modulate serum low density lipoprotein (LDL) levels
SRX CARDIO LLC12 citations80
US10821106B2Nov 3, 2020
Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity
SRX CARDIO LLC4 citations72
US11945782B2Apr 2, 2024
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity
SRX CARDIO LLC0 citations61
US11944619B2Apr 2, 2024
Phenylalanine small organic compounds to directly modulate PCSK9 protein activity
SRX CARDIO LLC0 citations61
US11925637B2Mar 12, 2024
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
SRX CARDIO LLC0 citations61
US11771710B2Oct 3, 2023
Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands
SRX CARDIO LLC0 citations61
US11026957B2Jun 8, 2021
Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands
SRX CARDIO LLC0 citations61
US11891369B2Feb 6, 2024
Compounds for binding proprotein convertase subtilisin/kexin type 9
SRX CARDIO LLC0 citations51
US12115154B2Oct 15, 2024
Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9)
SRX CARDIO LLC0 citations50
SEARLE & CO
11 patentsUS5451679ASep 19, 1995
2-chloro and 2-bromo derivatives of 1,5-iminosugars
SEARLE & CO32 citations96
US7115632B1Oct 3, 2006
Sulfonyl aryl or heteroaryl hydroxamic acid compounds
SEARLE & CO33 citations91
US6541489B1Apr 1, 2003
Aromatic sulfone hydroxamic acid metalloprotease inhibitor
SEARLE & CO21 citations90
US6426360B1Jul 30, 2002
4,5-substituted imidazolyl compounds for the treatment of inflammation
SEARLE & CO17 citations83
US5663342ASep 2, 1997
2-chloro and 2-bromo derivatives of 1,5-iminosugars
SEARLE & CO15 citations82
US5595981AJan 21, 1997
2-chloro and 2-bromo derivatives of 1,5-iminosugars
SEARLE & CO16 citations82
US6265439B1Jul 24, 2001
Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives
SEARLE & CO7 citations74
US5612480AMar 18, 1997
2-chloro and 2-bromo derivatives of 1,5-iminosugars
SEARLE & CO11 citations74
US5451604ASep 19, 1995
Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives
SEARLE & CO11 citations74
US6794511B2Sep 21, 2004
Sulfonyl aryl or heteroaryl hydroxamic acid compounds
SEARLE & CO2 citations63
US6583299B1Jun 24, 2003
α-amino-β-sulfonyl hydroxamic acid compounds
SEARLE & CO2 citations62
PHARMACIA CORP
10 patentsUS6750228B1Jun 15, 2004
Aromatic sulfone hydroxamic acid metalloprotease inhibitor
PHARMACIA CORP35 citations92
US6683093B2Jan 27, 2004
Aromatic sulfone hydroxamic acids and their use as protease inhibitors
PHARMACIA CORP27 citations92
US7119203B2Oct 10, 2006
Piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors
PHARMACIA CORP11 citations83
US6696449B2Feb 24, 2004
Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors
PHARMACIA CORP8 citations74
US6689794B2Feb 10, 2004
Aromatic sulfone hydroxamates and their use as protease inhibitors
PHARMACIA CORP12 citations73
US6656954B2Dec 2, 2003
Sulfonyl divalent aryl or heteroaryl hydroxamic acid compounds
PHARMACIA CORP3 citations63
US6750233B2Jun 15, 2004
Aromatic sulfone hydroxamic acid metalloprotease inhibitor
PHARMACIA CORP6 citations62
US6683078B2Jan 27, 2004
Use of sulfonyl aryl or heteroaryl hydroxamic acids and derivatives thereof as aggrecanase inhibitors
PHARMACIA CORP6 citations61
US6890937B2May 10, 2005
Aromatic sulfone hydroxamic acid metalloprotease inhibitor
PHARMACIA CORP4 citations60
US6890928B2May 10, 2005
Aromatic sulfone hydroxamic acids and their use as protease inhibitors
PHARMACIA CORP0 citations51