Inventor

DESJARLAIS JOHN

US87 patents

⚠️ This page may combine multiple inventors who share the name “DESJARLAIS JOHN”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

DESJARLAIS JOHN

XENCOR INC

Heterodimeric antibodies to CD3 X CD123

Heterodimeric proteins

Heterodimeric proteins

Optimized Fc variants

Heterodimeric antibodies that bind CD3 and tumor antigens

Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors

Bispecific checkpoint inhibitor antibodies

Fc variants with increased affinity for FcγRIIc

Bispecific heterodimeric fusion proteins containing IL-15-IL-15Rα Fc-fusion proteins and PD-1 antibody fragments

Heterodimeric antibodies that bind CD3 and CD38

Trispecific antibodies

Heterodimeric antibodies that bind CD3 and tumor antigens

Heterodimeric antibodies that bind CD3 and PSMA

Optimized Fc variants and methods for their generation

Optimized Fc variants

IL15/IL15Rα heterodimeric Fc-fusion proteins

Modulation of T cells with bispecific antibodies and FC fusions

Optimized Fc variants and methods for their generation

Heterodimeric antibodies to CD3 X CD20

Bispecific antibodies that bind to CD38 and CD3

Optimized FC variants and methods for their generation

Compositions and methods for treating IgE-mediated disorders

Compositions and methods for treating IgE-mediated disorders

Optimized Fc variants and methods for their generation

Optimized Fc variants

Heterodimeric antibodies that bind CD3 and PSMA

TIM-3 targeted heterodimeric fusion proteins containing IL-15/IL-15RA Fc-fusion proteins and TIM-3 antigen binding domains

Engineered IL-2 Fc fusion proteins

Optimized antibody variable regions

Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors

Heterodimeric antibodies that bind fibroblast activation protein

Heterodimeric proteins

Heterodimeric proteins

Optimized antibody variable regions

Fc variants with increased affinity for FcyRIIc

Heterodimeric proteins

Optimized Fc Variants

Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains

Optimized Fc variants

Optimized Fc variants and methods for their generation

IL-15/IL-15RA heterodimeric Fc fusion proteins and uses thereof

Heterodimeric antibodies that bind CD3 and tumor antigens

Heterodimeric antibodies that bind CD3 and tumor antigens

Heterodimeric proteins

Bispecific heterodimeric fusion proteins containing IL-15-IL-15Ralpha Fc-fusion proteins and immune checkpoint antibody fragments

LAZAR GREGORY ALAN

Fc variants having increased affinity for fcyrllc

Optimized Fc variants

Optimized Fc variants

DESJARLAIS JOHN

Compositions and methods for treating IgE-mediated disorders

MOORE GREGORY L

Rapid clearance of antigen complexes using novel antibodies